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My trajectory after a "vacation" and a new metastasis
My backgound briefly (full details in Profile): aggressive form, BRCA2 mutation, RP in 2017, then 39 sessions of radiation, and 3 yrs of Lupron. All at Smilow Cancer Hospital. As a result, my PSA was undetectable for 2.5 years, and in 9/21 I was put on a "vacation" from treatment. Then PSA started
My backgound briefly (full details in Profile): aggressive form, BRCA2 mutation, RP in 2017, then 39 sessions of radiation, and 3 yrs of Lupron. All at Smilow Cancer Hospital. As a result, my PSA was undetectable for 2.5 years, and in 9/21 I was put on a "vacation" from treatment. Then PSA started
Istomin
in
Advanced Prostate Cancer
7 months ago
What to do?
Hi All, At the end of August 2023 I completed 8 rounds of docetaxel. On 9/13/23 my PSA was 5.7, 10/30/23 8.25 and 11/27/23 it’s now 16.72. This year has been a shit show. I know my MO will put me on pluvicto. Here’s my quandary: I am a single gay man. Parents gone. No siblings. All I have to really
Hi All, At the end of August 2023 I completed 8 rounds of docetaxel. On 9/13/23 my PSA was 5.7, 10/30/23 8.25 and 11/27/23 it’s now 16.72. This year has been a shit show. I know my MO will put me on pluvicto. Here’s my quandary: I am a single gay man. Parents gone. No siblings. All I have to really
MJCA
in
Advanced Prostate Cancer
7 months ago
Sudden onset of severe leg pain
Yesterday my husband was strolling about the house as usual. Last night he experienced debilitating pain in his right thigh to the point he collapsed when trying to put weight on it, and then could not sleep because of the pain. He has needed a walker for even a few steps. We visited his PCP today
Yesterday my husband was strolling about the house as usual. Last night he experienced debilitating pain in his right thigh to the point he collapsed when trying to put weight on it, and then could not sleep because of the pain. He has needed a walker for even a few steps. We visited his PCP today
Tinuriel
in
Advanced Prostate Cancer
7 months ago
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Steroids and Radium 223
Hi Hopefully my husband will start Radium 223 in 4-6 weeks. He recently stopped abiraterone after 5 months as his PSA was doubling every month. While he was on abiraterone he was taking 2mgs of dexamethasone, although 1mg for the last month. He’s currently taking 6mgs of prednisilone but our question
Hi Hopefully my husband will start Radium 223 in 4-6 weeks. He recently stopped abiraterone after 5 months as his PSA was doubling every month. While he was on abiraterone he was taking 2mgs of dexamethasone, although 1mg for the last month. He’s currently taking 6mgs of prednisilone but our question
NLondon43
in
Advanced Prostate Cancer
7 months ago
Signatera tumor dna test
Has anyone heard of using the Signatera test from Natera to detect the presence of prostate cancer recurrence when PSA is rising but the PSMA PET scan is negative?
Has anyone heard of using the Signatera test from Natera to detect the presence of prostate cancer recurrence when PSA is rising but the PSMA PET scan is negative?
shihtzu124
in
Advanced Prostate Cancer
7 months ago
PSA Dropped after 22 days of Zytiga
On Nov 1, my cancer was diagnosed as castrate resistant. Abiraterone and Prednisone was added to Lupron. On November 3 I had a Lupron shot and started Abiraterone and Prednisone on November 10. Today I had a PSA test. My PSA dropped from 0.8 on November 1 to 0.44 today. I was not expecting such dramatic
On Nov 1, my cancer was diagnosed as castrate resistant. Abiraterone and Prednisone was added to Lupron. On November 3 I had a Lupron shot and started Abiraterone and Prednisone on November 10. Today I had a PSA test. My PSA dropped from 0.8 on November 1 to 0.44 today. I was not expecting such dramatic
dac500
in
Advanced Prostate Cancer
7 months ago
Final Path Report After RALP (Dad - 74, G7- 4+3) , what’s next ?
Hi All, I had posted about a month ago about my dad with G7 - 4+ 3. We originally thought there were bone Mets but it just turned out to be another bone anomaly identified in the PSMA PET scan. We went ahead with RALP and have shared the final path report here. While the MRI showed no signs of
Hi All, I had posted about a month ago about my dad with G7 - 4+ 3. We originally thought there were bone Mets but it just turned out to be another bone anomaly identified in the PSMA PET scan. We went ahead with RALP and have shared the final path report here. While the MRI showed no signs of
EzioAudi7
in
Advanced Prostate Cancer
7 months ago
BAT trial update
I commenced the trial about 2 months ago and I have now had 2 cycles of treatment consisting of testosterone injections and carboplatin infusions. 5 days ago I had my first CT and bone scans and the trial leader tells me my 3 detectable rib metastases are 'stable'. The stable assessment is good enough
I commenced the trial about 2 months ago and I have now had 2 cycles of treatment consisting of testosterone injections and carboplatin infusions. 5 days ago I had my first CT and bone scans and the trial leader tells me my 3 detectable rib metastases are 'stable'. The stable assessment is good enough
Bjry
in
Advanced Prostate Cancer
7 months ago
What is reco diet to take abi with food?
I am on Lupron and Abi two months now with <.1 PSA down from 2.2, MO says I can do abi w food if I want, so is it an okay idea to go with 500 or 250mg per day vs 1000, and if so, how many grams of fat constitute the low fat breakfast to eat with the abi? 🙂
I am on Lupron and Abi two months now with <.1 PSA down from 2.2, MO says I can do abi w food if I want, so is it an okay idea to go with 500 or 250mg per day vs 1000, and if so, how many grams of fat constitute the low fat breakfast to eat with the abi? 🙂
jackwfrench
in
Advanced Prostate Cancer
7 months ago
Detection of Small Cell Prostate Cancer
I understand Small Cell Prostate Cancer (SCPC) may produce less PSA. How do you detect SCPC? Is it detectable by PSMA PET/CT scan?
I understand Small Cell Prostate Cancer (SCPC) may produce less PSA. How do you detect SCPC? Is it detectable by PSMA PET/CT scan?
dac500
in
Advanced Prostate Cancer
7 months ago
Combine standard care with alternative care
The University of Maryland reported two cases of terminated PCs by combining standard care treatment with an alternative treatment. By reducing the PSAs to less than 3, the clioquinol + zinc killed more cancer than testosterone could renew, therefore termination. My PSA in three months went from 58
The University of Maryland reported two cases of terminated PCs by combining standard care treatment with an alternative treatment. By reducing the PSAs to less than 3, the clioquinol + zinc killed more cancer than testosterone could renew, therefore termination. My PSA in three months went from 58
agnut
in
Fight Prostate Cancer
7 months ago
PSA after Biopsy
I've heard that the biopsy procedure (14 cores) can elevate future PSA results. What is the recommended number of days or weeks to pass before scheduling a follow up PSA test? Thank you!
I've heard that the biopsy procedure (14 cores) can elevate future PSA results. What is the recommended number of days or weeks to pass before scheduling a follow up PSA test? Thank you!
Mpls
in
Prostate Cancer Network
7 months ago
5th Pluvicto tomorrow
My husband's lab work for tomorrow's treatment shows a new low on his PSA, 7.9. Again there are blood numbers that are in the "low" range but last time the Doctor Wasn't concerned and we were able to return to Mexico 3 days after treatment. His weight is down 10 lbs from last time but i be been sick
My husband's lab work for tomorrow's treatment shows a new low on his PSA, 7.9. Again there are blood numbers that are in the "low" range but last time the Doctor Wasn't concerned and we were able to return to Mexico 3 days after treatment. His weight is down 10 lbs from last time but i be been sick
Karirudy
in
Advanced Prostate Cancer
7 months ago
Low Volume Low PSA Metastatic PC.
When my Oncologist refers to Low volume, Low PSA Oglimetastic PC, what is he saying about my disease? I’ve been oo Abiraterone followed by Xtandi with Lupron every 3 months and Zometa every 6.
When my Oncologist refers to Low volume, Low PSA Oglimetastic PC, what is he saying about my disease? I’ve been oo Abiraterone followed by Xtandi with Lupron every 3 months and Zometa every 6.
NDJIM
in
Advanced Prostate Cancer
7 months ago
Rising PSA
Hi, have updated my profile to reflect recent changes. A gradual increase in PSA (1.2) with the prospect of changes to treatment if it continues at the current rate and gets near to 4. The oncologist is suggesting probably chemo but I would like to know more about other options before that discussion
Hi, have updated my profile to reflect recent changes. A gradual increase in PSA (1.2) with the prospect of changes to treatment if it continues at the current rate and gets near to 4. The oncologist is suggesting probably chemo but I would like to know more about other options before that discussion
FortyWinks
in
Advanced Prostate Cancer
7 months ago
Arx517 updates about the trial for metastatic castration resistant prostate cancer
”Following completion of the 21-day observation period at 3.4 mg/kg (Cohort 9), no dose limiting toxicities (DLTs) or serious adverse events (SAEs) were observed Two patients in Cohort 9 experienced rapid PSA reduction at three weeks post-treatment following the first ARX517 dose” https://www.biospace.com
”Following completion of the 21-day observation period at 3.4 mg/kg (Cohort 9), no dose limiting toxicities (DLTs) or serious adverse events (SAEs) were observed Two patients in Cohort 9 experienced rapid PSA reduction at three weeks post-treatment following the first ARX517 dose” https://www.biospace.com
Maxone73
in
Advanced Prostate Cancer
7 months ago
Zytiga after failing nubeqa ?
Has anyone had any luck with Zytiga after nubeqa fails to hold down PSA? I have been mCRPC for a few years now and Im curious if there is any chance Zytiga would work after the combination of Orgovyx/Nubeqa failed. I had some good results years ago when I was still nmCRPC with Firmagon/Xtandi, but had
Has anyone had any luck with Zytiga after nubeqa fails to hold down PSA? I have been mCRPC for a few years now and Im curious if there is any chance Zytiga would work after the combination of Orgovyx/Nubeqa failed. I had some good results years ago when I was still nmCRPC with Firmagon/Xtandi, but had
joeguy
in
Advanced Prostate Cancer
7 months ago
Zencor & XmAb
My MO discussed a clinical trial for me today if I qualify with the required genetic markers. My most recent PSMA scan showed further progression of metastasis in bone and lymph nodes and my PSA has increased fairly rapidly. Currently taking both Orgovyx & Nubeqa. I'm hoping some of the smart and
My MO discussed a clinical trial for me today if I qualify with the required genetic markers. My most recent PSMA scan showed further progression of metastasis in bone and lymph nodes and my PSA has increased fairly rapidly. Currently taking both Orgovyx & Nubeqa. I'm hoping some of the smart and
AllenMarco
in
Advanced Prostate Cancer
7 months ago
Diagnostic Imaging Not Yet Enough for Biopsy-Free Radical Prostatectomy - MedPage Today, November 27, 2023
Biopsy-free PCa diagnostics would be welcomed by anyone who has had one or more needle biopsies. This article in MedPage Today summarizes the current status for the several methodologies being studied as alternatives. Good info for those currently on AS or just watching a rising PSA. From the lead-in
Biopsy-free PCa diagnostics would be welcomed by anyone who has had one or more needle biopsies. This article in MedPage Today summarizes the current status for the several methodologies being studied as alternatives. Good info for those currently on AS or just watching a rising PSA. From the lead-in
cujoe
in
Fight Prostate Cancer
7 months ago
Can exercise lower your PSA?
https://youtu.be/hBFICfnOJ8A
https://youtu.be/hBFICfnOJ8A
Darryl
Partner
in
Prostate Cancer Network
7 months ago
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