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Which Treatment for These Biopsy Results?
I now have my biopsy results Gleason 3 + 4 ie 90% of 3 and 10% of 4 Grade 2 The consultant said it was Intermediate but at one point used the term Low intermediate. Is this latter term valid given the stats? T2a NO MO - but I am puzzled about this because although it was mostly all on the left side
I now have my biopsy results Gleason 3 + 4 ie 90% of 3 and 10% of 4 Grade 2 The consultant said it was Intermediate but at one point used the term Low intermediate. Is this latter term valid given the stats? T2a NO MO - but I am puzzled about this because although it was mostly all on the left side
Nordman
in
Advanced Prostate Cancer
6 months ago
SRBT and EXTEND trial
Does anybody have the full text of EXTEND trial results from June 2023? (my payment attempt is rejected and the tips on how to get a study without cost doesn´t work) https://pubmed.ncbi.nlm.nih.gov/37022702/ Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic
Does anybody have the full text of EXTEND trial results from June 2023? (my payment attempt is rejected and the tips on how to get a study without cost doesn´t work) https://pubmed.ncbi.nlm.nih.gov/37022702/ Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic
Purple-Bike
in
Advanced Prostate Cancer
6 months ago
What is the next step
I have one more Immunotherapy for my bladder cancer, so far all scan have shown no metastasis. Now I need to focus on my PC after more than a year of ignoring it. My PSA has been fluctuating and is now 0.65, doubling time is 16 months, I have not had ADT yet and my MO wants to just wait and watch. What
I have one more Immunotherapy for my bladder cancer, so far all scan have shown no metastasis. Now I need to focus on my PC after more than a year of ignoring it. My PSA has been fluctuating and is now 0.65, doubling time is 16 months, I have not had ADT yet and my MO wants to just wait and watch. What
old64horn
in
Advanced Prostate Cancer
6 months ago
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CDK 12 mutation and Immunotherapy
Hi All, My PSA as is starting to rise on Arbi/Dexa. I have the CDK12 mutation which is apparently known to be a drug target or to predict sensitivity to Atezolizumab (Tecentriq PD-1 Checkpoint Inhibitor), hence there is open Immunotherapy trial called BoB (NCT03767075). I meet the trial doctor next
Hi All, My PSA as is starting to rise on Arbi/Dexa. I have the CDK12 mutation which is apparently known to be a drug target or to predict sensitivity to Atezolizumab (Tecentriq PD-1 Checkpoint Inhibitor), hence there is open Immunotherapy trial called BoB (NCT03767075). I meet the trial doctor next
MikeMartin
in
Advanced Prostate Cancer
6 months ago
Erectile dysfunction
Hi My first post, I think it is pretty obvious that many of us, me included, associate our self worth, status with our 'masculinity'. This may or may not be a good thing, but many, most men in fact consider themselves to be profoundly binary. They represent the '1' to a feminine '0'. When a man fails
Hi My first post, I think it is pretty obvious that many of us, me included, associate our self worth, status with our 'masculinity'. This may or may not be a good thing, but many, most men in fact consider themselves to be profoundly binary. They represent the '1' to a feminine '0'. When a man fails
Iro1
in
Sensitive Issues for Men
6 months ago
Is there any order to when new medications or PARP inhibitor are tried?
My medical oncologist is hell bent on me doing Lu 177 pluvicto next, I was hoping to try other things first… Medical Oncologist suggested waiting for the next two months to see if PSA is still rising…and to do a pet scan Diagnosed 06/2022 Gleason 8/9 Oligo metastatic 3 lytic lesions two resolved
My medical oncologist is hell bent on me doing Lu 177 pluvicto next, I was hoping to try other things first… Medical Oncologist suggested waiting for the next two months to see if PSA is still rising…and to do a pet scan Diagnosed 06/2022 Gleason 8/9 Oligo metastatic 3 lytic lesions two resolved
Shorehousejam
in
Fight Prostate Cancer
6 months ago
Question, each month with rising PSA, when do I do a pet scan
Medical Oncologist suggested waiting for the next two months to see if it’s still rising… Diagnosed 06/2022 Gleason 8/9 Oligo metastatic 3 lytic lesions two resolved Started Firmagon 7/6/2022 Zytiga with Prednisone 7/20/2022 currently still on these meds Docetaxel Chemotherapy on 08/11/2022
Medical Oncologist suggested waiting for the next two months to see if it’s still rising… Diagnosed 06/2022 Gleason 8/9 Oligo metastatic 3 lytic lesions two resolved Started Firmagon 7/6/2022 Zytiga with Prednisone 7/20/2022 currently still on these meds Docetaxel Chemotherapy on 08/11/2022
Shorehousejam
in
Advanced Prostate Cancer
6 months ago
Post SBRT Day 9 - 15
Continuing my reporting on my experience after 5 SBRT treatments with focal boost, Barrigel spacer, urethral steering to try and avoid GU side effects. I am 68, in good shape, one 4+3, one 3+3, Decipher .84, PSA 7.8, PSMA PET confined to prostate, 6 months Orgovyx. Flomax started with treatment and
Continuing my reporting on my experience after 5 SBRT treatments with focal boost, Barrigel spacer, urethral steering to try and avoid GU side effects. I am 68, in good shape, one 4+3, one 3+3, Decipher .84, PSA 7.8, PSMA PET confined to prostate, 6 months Orgovyx. Flomax started with treatment and
ToolBeltZia
in
Prostate Cancer Network
6 months ago
Letting Go
If it is one thing that I have after almost 18 years of playing this game, it is a story or perhaps many stories. So Many chapters. What I am about to say may seem easy from the perspective of undetectable PSA and clear scans these past 10 years. I assure you that at the time there was nothing easy about
If it is one thing that I have after almost 18 years of playing this game, it is a story or perhaps many stories. So Many chapters. What I am about to say may seem easy from the perspective of undetectable PSA and clear scans these past 10 years. I assure you that at the time there was nothing easy about
Todd1963
in
Advanced Prostate Cancer
6 months ago
Concern - At 4 mo on Lupron/Abi, Testosterone hits 40
While PSA was again <.1 yesterday, testosterone jumped to 40 ng/dl or 1.4 nmole/L, which is a big move toward the 1.7 danger zone for faster movement toward CRPC ( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472467/ ) , and I am interested
While PSA was again <.1 yesterday, testosterone jumped to 40 ng/dl or 1.4 nmole/L, which is a big move toward the 1.7 danger zone for faster movement toward CRPC ( https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472467/ ) , and I am interested
jackwfrench
in
Advanced Prostate Cancer
6 months ago
RT results look good
After a bout of sepsis from a directed biopsy, 5 weeks of RT and 3 months of Eligard, my tests show undetectable PSA. I'm still dealing with side effects (interrupted sleep, urinary and bowel differences) but happy to report it looks like, for the time being, that my stage 2/3 PC may have been beaten
After a bout of sepsis from a directed biopsy, 5 weeks of RT and 3 months of Eligard, my tests show undetectable PSA. I'm still dealing with side effects (interrupted sleep, urinary and bowel differences) but happy to report it looks like, for the time being, that my stage 2/3 PC may have been beaten
Eadgbe
in
Fight Prostate Cancer
6 months ago
PSA 6 months after RT
Here is a review of a presentationby Dr. Ravi at ASCO 2023, regarding measuring the PSA at 6 months post radiation treatment, for all risk groups. He found that the 6-month post-RT PSA was highly prognostic of 5- and 10-year rates of metastasis free survival (MFS), Overall Survival (OS), and prostate
Here is a review of a presentationby Dr. Ravi at ASCO 2023, regarding measuring the PSA at 6 months post radiation treatment, for all risk groups. He found that the 6-month post-RT PSA was highly prognostic of 5- and 10-year rates of metastasis free survival (MFS), Overall Survival (OS), and prostate
janebob99
in
Prostate Cancer Network
6 months ago
LIQUID BIOPSY: Hello friends, what do you know about Liquid biopsy of circulating tumor ctDNA? Is it usefull with 6.2 PSA ?
Hello friends, what do you know about Liquid biopsy of circulating tumor ctDNA? Is it usefull with 6.2 PSA ? Depending on the results do we get access to some novel drugs like olapariv or nivolumab, etc, that might help us ? 🫠thanks, Manilo.
Hello friends, what do you know about Liquid biopsy of circulating tumor ctDNA? Is it usefull with 6.2 PSA ? Depending on the results do we get access to some novel drugs like olapariv or nivolumab, etc, that might help us ? 🫠thanks, Manilo.
Manilo
in
Advanced Prostate Cancer
6 months ago
Update on my father
Dad was diagnosed in 2016 stage 4, bones and lymphnodes. We dont have a gleason score because his diagnoses was found through a hip xray after a fall and they biopsied his hip. He has had lupron, xgeva, bicalutamide and now he is on Xtandi. Dads last bone scan psa were July 8th. His bone scan showed
Dad was diagnosed in 2016 stage 4, bones and lymphnodes. We dont have a gleason score because his diagnoses was found through a hip xray after a fall and they biopsied his hip. He has had lupron, xgeva, bicalutamide and now he is on Xtandi. Dads last bone scan psa were July 8th. His bone scan showed
Radtech40
in
Advanced Prostate Cancer
6 months ago
Testosterone was nearly back to normal, then dropped
I had a year of Lupron and Enzalutamide in 2022. Testosterone slowly came back to a high of about 240 in June and Sept 2023. Normal for me is around 350 - 375. Now this week T is down to 156. Is this sort of fluctuation normal? I had 6 months of ADT in connection with radiation for recurrent PCa
I had a year of Lupron and Enzalutamide in 2022. Testosterone slowly came back to a high of about 240 in June and Sept 2023. Normal for me is around 350 - 375. Now this week T is down to 156. Is this sort of fluctuation normal? I had 6 months of ADT in connection with radiation for recurrent PCa
Teddy28
in
Advanced Prostate Cancer
6 months ago
Discontinue all antioxidant supplements on early signs of biochemical recurrence?
The latest literature appears to indicate a PSA as low as 0.03, regardless of the multi-result dynamics is a reliable very early confirmation of biochemical recurrence. Maybe it's arguable some rare cases may "slip through" and stabilize without further treatment but data from the latest studies is
The latest literature appears to indicate a PSA as low as 0.03, regardless of the multi-result dynamics is a reliable very early confirmation of biochemical recurrence. Maybe it's arguable some rare cases may "slip through" and stabilize without further treatment but data from the latest studies is
jazj
in
Advanced Prostate Cancer
6 months ago
BONE DENSITY TEST IS BAD
I am 68 with low volume metastatic to hip bones. Nothing elsewhere, at this time. Had PSA of 125 last April, and oncologist put me on Relogolix and Darolutemide. That along with going to plant based diet and adding weights and HITT exercise 3-4x per week, has brought me down to < .006. that’s the
I am 68 with low volume metastatic to hip bones. Nothing elsewhere, at this time. Had PSA of 125 last April, and oncologist put me on Relogolix and Darolutemide. That along with going to plant based diet and adding weights and HITT exercise 3-4x per week, has brought me down to < .006. that’s the
JL1955
in
Advanced Prostate Cancer
6 months ago
Full circle with this disease
Diagnosed 2017 PSA 105 started ADT, 6 rounds Docetaxel and radiation PSA drops to undetectable. Castrate resistant 2022 started Abiraterone and prednisone this failed after 3 months. Start Xgeva and Xofigo 2023. PSA back at 105 November 2023. Start 10 rounds of Docetaxel and PSA starts dropping again
Diagnosed 2017 PSA 105 started ADT, 6 rounds Docetaxel and radiation PSA drops to undetectable. Castrate resistant 2022 started Abiraterone and prednisone this failed after 3 months. Start Xgeva and Xofigo 2023. PSA back at 105 November 2023. Start 10 rounds of Docetaxel and PSA starts dropping again
Islandboy2021
in
Advanced Prostate Cancer
6 months ago
Confusing CT scan results
My PSA has been rising slowly after prostate removal two years ago. Was at zero months after and slowly rising at .02,.03. .05, .06. .09 and then .13. My doctor ordered CT and bone scans. Bone scan came back clear and then CT scan showed a few things in bones and a nonspecific mass outside the liver
My PSA has been rising slowly after prostate removal two years ago. Was at zero months after and slowly rising at .02,.03. .05, .06. .09 and then .13. My doctor ordered CT and bone scans. Bone scan came back clear and then CT scan showed a few things in bones and a nonspecific mass outside the liver
Jens99
in
Advanced Prostate Cancer
6 months ago
PLUVICTO.................
Getting ready for my 5th infusion of Pluvicto. The side effects usually ground me for two to three weeks, and i always say that i am through, and can't stand anymore. When i started, my PSA was 42 + a point. It went down to 22+ a point and as of today it is 10.6. I have been boarding my dog,
Getting ready for my 5th infusion of Pluvicto. The side effects usually ground me for two to three weeks, and i always say that i am through, and can't stand anymore. When i started, my PSA was 42 + a point. It went down to 22+ a point and as of today it is 10.6. I have been boarding my dog,
PianoMan3048
in
Men's Health Forum
6 months ago
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