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The role of istradefylline in the Parkinson's disease armamentarium
https://pubmed.ncbi.nlm.nih.gov/37029952 Expert opinion: Istradefylline is safe and well tolerated. Its efficacy was pronounced, when patients were on a lower chronic oral levodopa regimen. Levodopa causes a homocysteine elevation, which reflects an impaired methylation potential. As a result, an up
https://pubmed.ncbi.nlm.nih.gov/37029952 Expert opinion: Istradefylline is safe and well tolerated. Its efficacy was pronounced, when patients were on a lower chronic oral levodopa regimen. Levodopa causes a homocysteine elevation, which reflects an impaired methylation potential. As a result, an up
Hidden
in
Cure Parkinson's
1 year ago
3 Years After Stage IV Diagnosis
It was three years ago today that my wonderful, sweet husband was diagnosed with Stage IV prostate cancer. I can still remember the shock when we heard the news. We thought his diagnosis meant he would die soon. We didn't know at the time that if you respond well to treatment you can live years with
It was three years ago today that my wonderful, sweet husband was diagnosed with Stage IV prostate cancer. I can still remember the shock when we heard the news. We thought his diagnosis meant he would die soon. We didn't know at the time that if you respond well to treatment you can live years with
Avanat
in
Advanced Prostate Cancer
1 year ago
Junctional Rhythm
I have had Paroxysmal Afib since 2017, and take Warfarin and Bisoprolol ( now been 5mgs twice daily for a year ). No other drugs. I have been having a lot of unclassified results on my Kardia lately. A few is normal and I always thought it was interference or similar, or me not being still enough. However
I have had Paroxysmal Afib since 2017, and take Warfarin and Bisoprolol ( now been 5mgs twice daily for a year ). No other drugs. I have been having a lot of unclassified results on my Kardia lately. A few is normal and I always thought it was interference or similar, or me not being still enough. However
Tellingfibs
in
Atrial Fibrillation Support
1 year ago
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Clinical Trials
https://copdnewstoday.com/news/dupixent-prevents-copd-exacerbations-improves-lung-function-trial/?utm_source=COPD&utm_campaign=91d7e6df2c-COPD_ENL_3.0_NON-US&utm_medium=email&utm_term=0_23d08524e9-91d7e6df2c-73825653 Ken
https://copdnewstoday.com/news/dupixent-prevents-copd-exacerbations-improves-lung-function-trial/?utm_source=COPD&utm_campaign=91d7e6df2c-COPD_ENL_3.0_NON-US&utm_medium=email&utm_term=0_23d08524e9-91d7e6df2c-73825653 Ken
Elpojohn
in
Lung Conditions Community Forum
1 year ago
Oligometastatic prostate cancer: Reality or figment of imagination?
New paper below, [1] full text. Oligometastatic PCa has been controversial from the start, with some denying that it exists. "If you have one met, you have many - you just can't see them." Then there is the counting problem. One study indicated that a few spinal mets visible on a bone scan were oligometastatic
New paper below, [1] full text. Oligometastatic PCa has been controversial from the start, with some denying that it exists. "If you have one met, you have many - you just can't see them." Then there is the counting problem. One study indicated that a few spinal mets visible on a bone scan were oligometastatic
pjoshea13
in
Fight Prostate Cancer
1 year ago
Aspirin75mg / gnawing pain
Hi,Following a long period of very high number of ectopics (now much calmer) my meds are Lipitor40,Bisoprolol 2.5mg and Aspirin75mg. Of late I ve been getting a wave of discomfort emanating in the left chest. Not so much pain just an uncomfortable gnawing sensation. No appts available for a few weeks
Hi,Following a long period of very high number of ectopics (now much calmer) my meds are Lipitor40,Bisoprolol 2.5mg and Aspirin75mg. Of late I ve been getting a wave of discomfort emanating in the left chest. Not so much pain just an uncomfortable gnawing sensation. No appts available for a few weeks
talipia
in
AF Association
1 year ago
New here
Hello everyone I'm a woman in my 60s and was first diagnosed with paroxysmal AFib about a year ago. I've been having an episode about every 4-5 months and was prescribed Flecainide to be taken at the onset of an episode and that seems to stop it within about half an hour, luckily. Unfortunately,
Hello everyone I'm a woman in my 60s and was first diagnosed with paroxysmal AFib about a year ago. I've been having an episode about every 4-5 months and was prescribed Flecainide to be taken at the onset of an episode and that seems to stop it within about half an hour, luckily. Unfortunately,
TopBiscuit
in
AF Association
1 year ago
Addition of Metastasis-Directed Therapy to Intermittent Hormone Therapy for Oligometastatic PC. The EXTEND Phase 2 Randomized Clinical Trial
MDT and intermittent ADT offer a progression free survival advantage when compared with intermittent ADT alone. "MDT facilitated a longer time with eugonadal testosterone as part of an intermittent hormone therapy strategy." "Time to new lesion failure was longer for patients randomized to combined
MDT and intermittent ADT offer a progression free survival advantage when compared with intermittent ADT alone. "MDT facilitated a longer time with eugonadal testosterone as part of an intermittent hormone therapy strategy." "Time to new lesion failure was longer for patients randomized to combined
tango65
in
Advanced Prostate Cancer
1 year ago
Confused
Diagnosed with afib before Xmas and given 2.5 bisoprolol Waiting for appointment with cardiologist.On a visit recently to nurse at GP surgery for BP check,I mentioned that I suffered dizzyness with meds.Later that day got a phone call from her saying that doctor had dropped dose to 1.25.Surely this would
Diagnosed with afib before Xmas and given 2.5 bisoprolol Waiting for appointment with cardiologist.On a visit recently to nurse at GP surgery for BP check,I mentioned that I suffered dizzyness with meds.Later that day got a phone call from her saying that doctor had dropped dose to 1.25.Surely this would
TheGrinch2
in
AF Association
1 year ago
Statins
I just finished watching - https://www.youtube.com/watch?v=0MSNUjQt0u0 I find it fascinating that doctors are aware that statins don't work on dialysis patients, even the KDIGO guidelines say not to prescribe them, and yet doctors still will go ahead and lower LDL using statins. I know I am on one .
I just finished watching - https://www.youtube.com/watch?v=0MSNUjQt0u0 I find it fascinating that doctors are aware that statins don't work on dialysis patients, even the KDIGO guidelines say not to prescribe them, and yet doctors still will go ahead and lower LDL using statins. I know I am on one .
bumblebee_tuna
in
Kidney Dialysis
1 year ago
Statins for paroxysmal Atrial Fibulation?
Hello Everyone. I have P-Afib which is well managed with Verapamil 120mcg. I take Ramiprimil 5mg and Apixaban. I'm lucky my Afib has remained mild once on this treatment for the last two /three years - hopefully will stay that way- providing I keep taking Verapamil. I get the odd flutter for a few seconds
Hello Everyone. I have P-Afib which is well managed with Verapamil 120mcg. I take Ramiprimil 5mg and Apixaban. I'm lucky my Afib has remained mild once on this treatment for the last two /three years - hopefully will stay that way- providing I keep taking Verapamil. I get the odd flutter for a few seconds
waveylines
in
Atrial Fibrillation Support
1 year ago
Accuracy of heart monitors during exercise
When I was recently diagnosed with AF I was told by a BHF nurse that the majority of HR monitors can't give an accurate reading due to the inconsistency of heartbeats. Yet I'm often reading concerns on this forum about HR readings on fitness monitors, fitbits etc. and wonder if there is a truly accurate
When I was recently diagnosed with AF I was told by a BHF nurse that the majority of HR monitors can't give an accurate reading due to the inconsistency of heartbeats. Yet I'm often reading concerns on this forum about HR readings on fitness monitors, fitbits etc. and wonder if there is a truly accurate
Rainfern
in
AF Association
1 year ago
Bipolar Androgen Therapy Followed by Androgen Receptor Inhibition as Sequential Therapy for Prostate Cancer
Here's a treat - a review of BAT (Bipolar Androgen Therapy), actually written by Dr. Sam Denmeade [1]. In his intro, he makes a point of stressing that androgen receptor axis therapies are "highly effective [i]
palliative
[/i] therapy, but they are
not curative
." A few years ago it was
Here's a treat - a review of BAT (Bipolar Androgen Therapy), actually written by Dr. Sam Denmeade [1]. In his intro, he makes a point of stressing that androgen receptor axis therapies are "highly effective [i]
palliative
[/i] therapy, but they are
not curative
." A few years ago it was
pjoshea13
in
Fight Prostate Cancer
1 year ago
Clinical Trial with BGB-11417
Hi all! Would love to hear from anyone who is participating in / has considered and/or has knowledge of the NCT trial 04277637 - the Non-Randomized, Open-Label trial investigating the novel BCL-2 inhibitor BGB-11417? I am approaching my first treatment for CLL and my CLL specialist is a PI in this
Hi all! Would love to hear from anyone who is participating in / has considered and/or has knowledge of the NCT trial 04277637 - the Non-Randomized, Open-Label trial investigating the novel BCL-2 inhibitor BGB-11417? I am approaching my first treatment for CLL and my CLL specialist is a PI in this
Chi-town_Girl
in
CLL Support
1 year ago
new to this forum
hello to everyone from New Mexico, US. I am finding out more about heart issues here on this forum than from my EP and cardiologist combined! Thank you all. I am 69 and had one of the first open heart surgeries done in Los Angeles at 9 years. ( for an ASD) There is still a small leak but mostly corrected
hello to everyone from New Mexico, US. I am finding out more about heart issues here on this forum than from my EP and cardiologist combined! Thank you all. I am 69 and had one of the first open heart surgeries done in Los Angeles at 9 years. ( for an ASD) There is still a small leak but mostly corrected
Petaca
in
Anticoagulation Support
1 year ago
Full Blood Count Test Results
Hiya, I’ve had a lot of help on this forum in regards to making some sense of my thyroid blood test results and I was wondering if anyone is able to advise with these results too. They are out of date as they are from December 2022 but they are the tests I was given when my hypothyroid symptoms started
Hiya, I’ve had a lot of help on this forum in regards to making some sense of my thyroid blood test results and I was wondering if anyone is able to advise with these results too. They are out of date as they are from December 2022 but they are the tests I was given when my hypothyroid symptoms started
NiaJayne
in
Thyroid UK
1 year ago
Is there such a thing as ‘slow AFib?’
Hello all! St Barts in London have offered me an ablation! Taunton referred me to Bristol but they were unwilling because I also have hypertrophic cardiomyopathy and they didn’t have a good success rate for people like me.☹️ I was then referred to St Barts and they have said they’ll give it a go.
Hello all! St Barts in London have offered me an ablation! Taunton referred me to Bristol but they were unwilling because I also have hypertrophic cardiomyopathy and they didn’t have a good success rate for people like me.☹️ I was then referred to St Barts and they have said they’ll give it a go.
Slidingdoors99
in
Atrial Fibrillation Support
1 year ago
Involvement Opportunity - PRaCTicAL Research Project (UK)
The British Liver Trust are excited to be working with NHS Lothian, University of Edinburgh, Scottish National Blood Transfusion Services (SNBTS) and Cell and Gene Therapy Catapult as part of a collaboration to create the first ‘Centre for Precision Cell Therapy for the Liver’ in the world. PRaCTicAL
The British Liver Trust are excited to be working with NHS Lothian, University of Edinburgh, Scottish National Blood Transfusion Services (SNBTS) and Cell and Gene Therapy Catapult as part of a collaboration to create the first ‘Centre for Precision Cell Therapy for the Liver’ in the world. PRaCTicAL
BritishLiverTrust1
Partner
in
British Liver Trust
1 year ago
Iron regulation offers new treatment hope for incurable blood cancer
Published April 4, 2023 | Originally published on MedicalXpress Breaking News-and-Events A landmark discovery linking iron regulation to a rare blood cancer has led to clinical trials of a potential new treatment for patients with the incurable disease. The study focused on polycythemia vera (PV),
Published April 4, 2023 | Originally published on MedicalXpress Breaking News-and-Events A landmark discovery linking iron regulation to a rare blood cancer has led to clinical trials of a potential new treatment for patients with the incurable disease. The study focused on polycythemia vera (PV),
PhysAssist
in
MPN Voice
1 year ago
Ectopic beats , 7yrs after rf ablation
Hi all , I've been good now for around 7yrs after rf ablation , got on with life running, gym , all good , so this week I felt tight in my chest with a few thumps checked my pulse and there's ectopic beats , pulse is fine , blood pressure fine , attended a&e they picked up the ectopic on ecg , did bloods
Hi all , I've been good now for around 7yrs after rf ablation , got on with life running, gym , all good , so this week I felt tight in my chest with a few thumps checked my pulse and there's ectopic beats , pulse is fine , blood pressure fine , attended a&e they picked up the ectopic on ecg , did bloods
Runcrans
in
AF Association
1 year ago
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