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phase 1 clinical trials at Royal Marsden — anyone has experience?
hi all .. I’ve been offered either a phase 1 clinical trial or a phase 3 clinical trial at the Royal Marsden . The difference is that in phase 1 , a possible new drug is having its first tests but in phase 3 , the drug has been shown to work in some patients and may move to being approved. however ,
hi all .. I’ve been offered either a phase 1 clinical trial or a phase 3 clinical trial at the Royal Marsden . The difference is that in phase 1 , a possible new drug is having its first tests but in phase 3 , the drug has been shown to work in some patients and may move to being approved. however ,
Lookingahead
in
My Ovacome
2 years ago
palpitations and hyper/graves
hi, diagnosed Aug 21, numbers all now in range according to endo but my heart continues to race, often. Had ecg all ok, waiting for a 3 day ecg tape. Endo is certain this is not to do with thyroid, although never had an issue till now. latest results she gave me : Ft3 4.2 Ft4 17 TSh 4.4 Should I
hi, diagnosed Aug 21, numbers all now in range according to endo but my heart continues to race, often. Had ecg all ok, waiting for a 3 day ecg tape. Endo is certain this is not to do with thyroid, although never had an issue till now. latest results she gave me : Ft3 4.2 Ft4 17 TSh 4.4 Should I
Cebeez
in
Thyroid UK
2 years ago
After 11 years, dad has started chemo for the first time
Hey all, dad was diagnosed in Feb 2012 (removed prostate right away), metastasized to the coccyx in 2019. Been on Zoladex (for life), Zytiga, Xtandi, etc. Now that his PSA is very slowly increasing (been going up since 2019 from below 0.30 to now at 2.0+), his oncologist recommended we enroll him in
Hey all, dad was diagnosed in Feb 2012 (removed prostate right away), metastasized to the coccyx in 2019. Been on Zoladex (for life), Zytiga, Xtandi, etc. Now that his PSA is very slowly increasing (been going up since 2019 from below 0.30 to now at 2.0+), his oncologist recommended we enroll him in
PHnerd
in
Advanced Prostate Cancer
2 years ago
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afib and blood pressure
Hello all, paramedics just left about half hour ago and I need to ask a question. My blood pressure shot up to 203/134 at my last reading before the paramedics arrived. They took blood pressure and said it was 177/97 they saw I was very anxious and stressed out. Asked if I wanted to be taken to emergency
Hello all, paramedics just left about half hour ago and I need to ask a question. My blood pressure shot up to 203/134 at my last reading before the paramedics arrived. They took blood pressure and said it was 177/97 they saw I was very anxious and stressed out. Asked if I wanted to be taken to emergency
kocoach
in
Atrial Fibrillation Support
2 years ago
Should I have an ablation?
Fortunately I’ve not had a repeat of the
atrial
flutter
. I’ve been told by the cardiac nurse that I’ve been referred for an ablation. I’m wondering if I need it? I’m in constant sinus rhythm now and the meds seem to be keeping the
atrial
flutter
at bay.
Fortunately I’ve not had a repeat of the
atrial
flutter
. I’ve been told by the cardiac nurse that I’ve been referred for an ablation. I’m wondering if I need it? I’m in constant sinus rhythm now and the meds seem to be keeping the
atrial
flutter
at bay.
Anon2023
in
British Heart Foundation
2 years ago
This helps you and us
Dear Particpants of Malecare's Prostate Cancer Community, I am asking you to support Malecare's help to men with prostate cancer and their families. Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge
Dear Particpants of Malecare's Prostate Cancer Community, I am asking you to support Malecare's help to men with prostate cancer and their families. Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge
Darryl
Partner
in
Prostate Cancer Caregivers
2 years ago
This helps you and us
Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge information, and innovative research. Indeed, no other prostate cancer nonprofit has produced more peer-reviewed papers and patented medical innovations
Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge information, and innovative research. Indeed, no other prostate cancer nonprofit has produced more peer-reviewed papers and patented medical innovations
Darryl
Partner
in
Prostate Cancer And Gay Men
2 years ago
Afib and Covid
What I had thought a few days ago was a cold, has turned out to be Covid. Here I was, prattling on about humidity and all the while, good old ‘Rona’ was brewing. My Afib had been a bit more evident in recent weeks, but not bothersome. My Covid seems to have peaked quickly and the headache and fever have
What I had thought a few days ago was a cold, has turned out to be Covid. Here I was, prattling on about humidity and all the while, good old ‘Rona’ was brewing. My Afib had been a bit more evident in recent weeks, but not bothersome. My Covid seems to have peaked quickly and the headache and fever have
Tellingfibs
in
Atrial Fibrillation Support
2 years ago
This is how to help you and us
Dear Particpants of Malecare's Prostate Cancer Community, I am asking you to support Malecare's help to men with prostate cancer and their families. Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge
Dear Particpants of Malecare's Prostate Cancer Community, I am asking you to support Malecare's help to men with prostate cancer and their families. Malecare is a national nonprofit organization that provides support groups, online support communities (like our Prostate Cancer community), cutting-edge
Darryl
Partner
in
Prostate Cancer Network
2 years ago
This is how to help you and us
Dear Particpants of Malecare's Advanced Prostate Cancer Community, I am asking you to support Malecare's help to men with prostate cancer and their families. Malecare is a national nonprofit organization that provides support groups, online support communities (like our Advanced Prostate Cancer community
Dear Particpants of Malecare's Advanced Prostate Cancer Community, I am asking you to support Malecare's help to men with prostate cancer and their families. Malecare is a national nonprofit organization that provides support groups, online support communities (like our Advanced Prostate Cancer community
Darryl
Partner
in
Advanced Prostate Cancer
2 years ago
M1774 plus Niraparib clinical trial
hi , has anyone been in the trial of M1774 either in its own or with Niraparib ? I have just been offered this at the Royal Marsden . Any feedback would be greatly appreciated!! Enjoy your Christmas all . Hopefully we can all forget about the big C for one day !!! x x
hi , has anyone been in the trial of M1774 either in its own or with Niraparib ? I have just been offered this at the Royal Marsden . Any feedback would be greatly appreciated!! Enjoy your Christmas all . Hopefully we can all forget about the big C for one day !!! x x
Lookingahead
in
My Ovacome
2 years ago
Any ideas on blood labs to monitor for earlier detection than PSA for becoming Castrate Resistant?
I am trying to get an idea of better test labs markers besides just the usual PSA for becoming castrat resistant, because if my SOC of ADT (Orgovyx, and Nubeqa) is starting to fail I would want to immediately jump on BAT. My doc always adds LDH. Conclusion: Our analysis suggested the association
I am trying to get an idea of better test labs markers besides just the usual PSA for becoming castrat resistant, because if my SOC of ADT (Orgovyx, and Nubeqa) is starting to fail I would want to immediately jump on BAT. My doc always adds LDH. Conclusion: Our analysis suggested the association
KocoPr
in
Advanced Prostate Cancer
2 years ago
Neuroprotective Properties of Green Tea (Camellia sinensis) in Parkinson’s Disease: A Review
Abstract Neurodegenerative disease is a collective term given for the clinical condition, which results in progressive degeneration of neurons and the loss of functions associated with the affected brain region. Apart from the increase in age, neurodegenerative diseases are also partly affected by diet
Abstract Neurodegenerative disease is a collective term given for the clinical condition, which results in progressive degeneration of neurons and the loss of functions associated with the affected brain region. Apart from the increase in age, neurodegenerative diseases are also partly affected by diet
Thal
in
Cure Parkinson's
2 years ago
BITE Clinical Study
My husband was told he only has two treatment options at this point. One is starting Jevtana, but at a lower than normal dose due to his neutrophils being only 1150. The other would be to participate in a clinical trial called BITE in Louisville. I am afraid I don’t recall what BITE is an acronym for
My husband was told he only has two treatment options at this point. One is starting Jevtana, but at a lower than normal dose due to his neutrophils being only 1150. The other would be to participate in a clinical trial called BITE in Louisville. I am afraid I don’t recall what BITE is an acronym for
Wyldhare22
in
Advanced Prostate Cancer
2 years ago
Ectopics and flecainide
Morning everyone. I have posted here recently concerning flecainide and received some very helpful information. Since being recommended this drug for my ectopic beats (which I have tried to 'live with') by an EP, my consultant has since suggested I try it as a pill in the pocket. The recommended dosage
Morning everyone. I have posted here recently concerning flecainide and received some very helpful information. Since being recommended this drug for my ectopic beats (which I have tried to 'live with') by an EP, my consultant has since suggested I try it as a pill in the pocket. The recommended dosage
DebbiB28
in
Arrhythmia Alliance
2 years ago
New drug approved for those with KRAS G-12C
On December 12th, 2022, the Food and Drug Administration (FDA) approved Krazati (adagrasib) for treatment of non-small cell lung cancer (nsclc) where there is a KRAS G12C mutation. This approval is for patients who have received at least one line of prior treatment such as chemotherapy. The FDA based
On December 12th, 2022, the Food and Drug Administration (FDA) approved Krazati (adagrasib) for treatment of non-small cell lung cancer (nsclc) where there is a KRAS G12C mutation. This approval is for patients who have received at least one line of prior treatment such as chemotherapy. The FDA based
Miranda_GO2
Partner
in
Lung Cancer Support
2 years ago
Urso blocks COVID - research today from Addenbrooke's Hospital, Cambridge
15h Dec 2022 at 14:15 UK time : On the BBC World Service programme Healthcheck, right now. Liver consultant from Addenbrooke's reporting that they have discovered that Urso protects against COVID. Medic says that Urso blocks COVID's ability to enter human cells. 'It shuts the doorway (into the cell
15h Dec 2022 at 14:15 UK time : On the BBC World Service programme Healthcheck, right now. Liver consultant from Addenbrooke's reporting that they have discovered that Urso protects against COVID. Medic says that Urso blocks COVID's ability to enter human cells. 'It shuts the doorway (into the cell
Wilderswimmer
in
PBCers Organization
2 years ago
Ideas to try to help fall asleep
I was thinking some of the drugs that help PC may also have effects such as insomnia, but I don't know sure. I have trouble myself, sleeping at times. For me, I know it is because my mind won't shut off, I am a worrier. Here are a couple things that may help to fall asleep. Try to wind down at
I was thinking some of the drugs that help PC may also have effects such as insomnia, but I don't know sure. I have trouble myself, sleeping at times. For me, I know it is because my mind won't shut off, I am a worrier. Here are a couple things that may help to fall asleep. Try to wind down at
Lrv44221
in
Advanced Prostate Cancer
2 years ago
Your best anti afib menu?
Everyone is different but this menu keeps me out of afib and being also low foodmap is healing my IBS A large spoon of ghee Raspberries Carrots (grated in summer and mashed in winter) with olive oil Sweat potatoes (boiled) Light boiled eggs Sardines (few times a week) Avocados (with lemon
Everyone is different but this menu keeps me out of afib and being also low foodmap is healing my IBS A large spoon of ghee Raspberries Carrots (grated in summer and mashed in winter) with olive oil Sweat potatoes (boiled) Light boiled eggs Sardines (few times a week) Avocados (with lemon
Sustainedvtach270
in
Atrial Fibrillation Support
2 years ago
Delivery of mRNA therapies: Moderna's founder Bob Langer discusses past, present, and future
[i]"mRNA is expected to become one of the major pillars of drug development. With an increasing number of concepts entering clinical trials, the first approval of an mRNA therapeutic against cancer is nearing" [/i]are the concluding lines of a review paper published in April 2021 https://molecular-cancer.biomedcentral.com
[i]"mRNA is expected to become one of the major pillars of drug development. With an increasing number of concepts entering clinical trials, the first approval of an mRNA therapeutic against cancer is nearing" [/i]are the concluding lines of a review paper published in April 2021 https://molecular-cancer.biomedcentral.com
bennevisplace
in
CLL Support
2 years ago
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