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The 2023 update of "Parkinson’s Disease Drug Therapies in the Clinical Trial Pipeline" is now available.
For those unfamiliar with this annual report, a good place to start might be Fig. 2 in the RESULTS section (a colour-coded diagram). https://content.iospress.com/articles/journal-of-parkinsons-disease/jpd239901
For those unfamiliar with this annual report, a good place to start might be Fig. 2 in the RESULTS section (a colour-coded diagram). https://content.iospress.com/articles/journal-of-parkinsons-disease/jpd239901
jeffreyn
in
Cure Parkinson's
1 year ago
post partum thyroiditis
Long story short(ish)- in October I had a baby, in December I was diagnosed with post partum thyroiditis with an over active thyroid(tsh <0.01) then levelled out a few weeks later before going underactive (tsh 11) around March time. My symptoms came as the results went out of range so even though they
Long story short(ish)- in October I had a baby, in December I was diagnosed with post partum thyroiditis with an over active thyroid(tsh <0.01) then levelled out a few weeks later before going underactive (tsh 11) around March time. My symptoms came as the results went out of range so even though they
Courtney96
in
Thyroid UK
1 year ago
Post Ablation AFib episodes .. frustrating
I had my Ablation about 3 1/2 months ago. I did not have any AFib recurrence that I'm aware of during the blanking period and was taking a beta blocker, a rhythm med, and anticoagulant. Was a bit rougher blanking than expected with early fever, regular headaches and low energy etc but no AFib! Hooray
I had my Ablation about 3 1/2 months ago. I did not have any AFib recurrence that I'm aware of during the blanking period and was taking a beta blocker, a rhythm med, and anticoagulant. Was a bit rougher blanking than expected with early fever, regular headaches and low energy etc but no AFib! Hooray
Banquo
in
Atrial Fibrillation Support
1 year ago
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Hi lovely ladies. Ok, so, diagnosed April 2021 Stage 1V HGSOC with spread to lymph nodes in neck and chest. No option of surgery because of spread. 6 rounds of Paclitaxel/Carboplatin. Reduction in tumour. Straight on to Avastin plus Olaparib (HRD negative). No more cancer in lymph nodes but slight progression
Hi lovely ladies. Ok, so, diagnosed April 2021 Stage 1V HGSOC with spread to lymph nodes in neck and chest. No option of surgery because of spread. 6 rounds of Paclitaxel/Carboplatin. Reduction in tumour. Straight on to Avastin plus Olaparib (HRD negative). No more cancer in lymph nodes but slight progression
Guilane
in
My Ovacome
1 year ago
Wrist blood pressure monitor
I was diagnosed with
atrial
flutter
this year and had an ablation in May and have an irregular heart beat which the EP said was normal for me. Any advise would be appreciated.
I was diagnosed with
atrial
flutter
this year and had an ablation in May and have an irregular heart beat which the EP said was normal for me. Any advise would be appreciated.
jaffacake8
in
British Heart Foundation
2 years ago
Clinical Trials
Hello Just wondering if anyone has considered clinical trials? I volunteered for this one vhttps://bepartofresearch.nihr.ac.uk/trial-details/trial-detail?trialId=31552&location=&distance= One more visit then back in a year's time to repeat again, the information is on the MSA webpage. Truthfully
Hello Just wondering if anyone has considered clinical trials? I volunteered for this one vhttps://bepartofresearch.nihr.ac.uk/trial-details/trial-detail?trialId=31552&location=&distance= One more visit then back in a year's time to repeat again, the information is on the MSA webpage. Truthfully
esj20
in
Multiple System Atrophy Trust
1 year ago
Interesting quiz via Medscape
https://reference.medscape.com/viewarticle/988436_2 I know you have to join to see the whole article but it is free.Pic is of first question which presumably was answered in the main by health care professionals. Hmmm. It also states that maintaining sinus rhythm does not reduce risk of stroke without
https://reference.medscape.com/viewarticle/988436_2 I know you have to join to see the whole article but it is free.Pic is of first question which presumably was answered in the main by health care professionals. Hmmm. It also states that maintaining sinus rhythm does not reduce risk of stroke without
Bagrat
in
AF Association
1 year ago
Radiation Treatment for Gleason 8 with Rectal Lymph Node
Looking for recommendations and advice....newly diagnosed . I am 67 PSA at annual physical March 1st was 26 then rose to 32 two weeks later with second test. Going to Mayo Clinic in Jacksonville. Have had an MRI, Biopsy, Gleason (4+4)=8, and PSMA Pet Scan last week confirming it has spread to my Rectal
Looking for recommendations and advice....newly diagnosed . I am 67 PSA at annual physical March 1st was 26 then rose to 32 two weeks later with second test. Going to Mayo Clinic in Jacksonville. Have had an MRI, Biopsy, Gleason (4+4)=8, and PSMA Pet Scan last week confirming it has spread to my Rectal
MustangGuy
in
Advanced Prostate Cancer
1 year ago
Confused (like a lot of us!)
After an Afib episode when I ended up calling an ambulance, the cardio put me on Flecainide 2x50mg daily, without actually seeing me. It has worked (touch wood) and I no longer have Afib episodes. A friend who also discovered he had Afib was immediately sent for an ablation. My question is what makes
After an Afib episode when I ended up calling an ambulance, the cardio put me on Flecainide 2x50mg daily, without actually seeing me. It has worked (touch wood) and I no longer have Afib episodes. A friend who also discovered he had Afib was immediately sent for an ablation. My question is what makes
Montsauton
in
AF Association
1 year ago
Endo/epicardial ablation
Does anyone have any knowledge or experience of this procedure for
atrial
flutter
/tachycardia.
Does anyone have any knowledge or experience of this procedure for
atrial
flutter
/tachycardia.
SophieBella
in
Heart Rhythm Disorders Support
2 years ago
WATCH one of the best BRAIN healing videos!
As previously mentioned in my posts ... I am not officially dx'd with PD. I have PD-like symptoms which I've held in 'check' since my self-diagnosis (and self-treatment) on June 20, 2021. ------------------------------------------------------- I routinely watch, listen, and skim through dozens of
As previously mentioned in my posts ... I am not officially dx'd with PD. I have PD-like symptoms which I've held in 'check' since my self-diagnosis (and self-treatment) on June 20, 2021. ------------------------------------------------------- I routinely watch, listen, and skim through dozens of
PDWarrior1900
in
Cure Parkinson's
1 year ago
Phase 3 SONIA Trial Challenges the Routine Practice of Using a 1st Line CDK4/6 Inhibitor in HR+, HER2- MBC
Apologies for the length, but I thought you might find this interesting! from: https://dailynews.ascopubs.org/do/sonia-challenges-need-first-line-use-cdk4-6-inhibitor-hr-positive-her2-negative?utm_source=newsletter&utm_medium=email&utm_campaign=The+OncoAlert+Newsletter+DAY+4+ASCO+2023&cmid=14f595bb-abce
Apologies for the length, but I thought you might find this interesting! from: https://dailynews.ascopubs.org/do/sonia-challenges-need-first-line-use-cdk4-6-inhibitor-hr-positive-her2-negative?utm_source=newsletter&utm_medium=email&utm_campaign=The+OncoAlert+Newsletter+DAY+4+ASCO+2023&cmid=14f595bb-abce
Bestbird
in
SHARE Metastatic Breast Cancer
1 year ago
PSMA PET scans
I am currently undergoing SBRT to three mets in my upper right lung as part of the comet 3 clinical trial. I would like to know how long I should wait before getting a PSMA PET scan I stopped taking Xtandi 2 weeks before treatment and will not start taking it again until 2 weeks after treatment
I am currently undergoing SBRT to three mets in my upper right lung as part of the comet 3 clinical trial. I would like to know how long I should wait before getting a PSMA PET scan I stopped taking Xtandi 2 weeks before treatment and will not start taking it again until 2 weeks after treatment
Ian996
in
Advanced Prostate Cancer
1 year ago
Biogen has disclosed plans to stop a late-stage clinical trial testing one of its drugs as a potential treatment for Parkinson's disease
The reasons are very absurd such as: According to a Monday announcement, the decision is due to several factors, including the trial’s complexity and run time. Results weren’t expected to come in until early 2031. Another, ongoing study evaluating the drug in early Parkinson’s patients will continue
The reasons are very absurd such as: According to a Monday announcement, the decision is due to several factors, including the trial’s complexity and run time. Results weren’t expected to come in until early 2031. Another, ongoing study evaluating the drug in early Parkinson’s patients will continue
Farooqji
in
Cure Parkinson's
1 year ago
Relapsed CLL: New Approaches Prolong Survival
With a median follow up of 41 months, AL demonstrated less
atrial
fibrillation/
atrial
flutter
, compared with IB (9.4% vs. 16.0%) with no difference in grade > 3 infections. Furthermore, AL's half-life being shorter than that of IB means that side effects are shorter lived."
With a median follow up of 41 months, AL demonstrated less
atrial
fibrillation/
atrial
flutter
, compared with IB (9.4% vs. 16.0%) with no difference in grade > 3 infections. Furthermore, AL's half-life being shorter than that of IB means that side effects are shorter lived."
Jm954
Administrator
in
CLL Support
1 year ago
where I’m at and what docs suggest
hello all I have occasional episodes of AFib up to 5 days a couple of times a year but have been having more shorter episodes for a few seconds or minutes at times, very occasionally at night when sleeping on my stomach. So a change. I take apixaban. My life is normal other than tiredness probably
hello all I have occasional episodes of AFib up to 5 days a couple of times a year but have been having more shorter episodes for a few seconds or minutes at times, very occasionally at night when sleeping on my stomach. So a change. I take apixaban. My life is normal other than tiredness probably
FiveMilesSouth
in
AF Association
1 year ago
More from PubMed
1. Magnetic resonance imaging (MRI) for local staging before salvage radical prostatectomy: a meta-analysis. Zapała P, Ślusarczyk A, Rajwa P, Gandaglia G, Zapała Ł, Zattoni F, Lorenc T, Ploussard G, Radziszewski P. World J Urol. 2023 May;41(5):1275-1284. doi: 10.1007/s00345-023-04383-2. Epub 2023 Apr
1. Magnetic resonance imaging (MRI) for local staging before salvage radical prostatectomy: a meta-analysis. Zapała P, Ślusarczyk A, Rajwa P, Gandaglia G, Zapała Ł, Zattoni F, Lorenc T, Ploussard G, Radziszewski P. World J Urol. 2023 May;41(5):1275-1284. doi: 10.1007/s00345-023-04383-2. Epub 2023 Apr
Magnus1964
in
Advanced Prostate Cancer
1 year ago
Latest from PubMed
1. Efficacy in urinary symptom burden, psychological distress, and self-efficacy of education-enhanced interventions in prostate cancer patients: a systematic review and meta-analyses. Martín-Núñez J, Raya-Benítez J, López-López L, Calvache-Mateo A, Heredia-Ciuró A, Navas-Otero A, Valenza MC. Support
1. Efficacy in urinary symptom burden, psychological distress, and self-efficacy of education-enhanced interventions in prostate cancer patients: a systematic review and meta-analyses. Martín-Núñez J, Raya-Benítez J, López-López L, Calvache-Mateo A, Heredia-Ciuró A, Navas-Otero A, Valenza MC. Support
Magnus1964
in
Advanced Prostate Cancer
1 year ago
WHOOPS
I just spoke with my doctors nurse and it shows you can always learn new things and you can also mess things up. Lol. I hadn’t mentioned much about being a little bit nervous regarding my new pacemaker. The past two days my heart rate has been up. I am set for 80. I have noticed, and I know that my
I just spoke with my doctors nurse and it shows you can always learn new things and you can also mess things up. Lol. I hadn’t mentioned much about being a little bit nervous regarding my new pacemaker. The past two days my heart rate has been up. I am set for 80. I have noticed, and I know that my
DawnTX
in
AF Association
1 year ago
Tanta Anna Updatw
I’m hoping you remember my past posts I’ve been on a series of meditation trials - is what I’ll call them After my four ablations last one from the highly recognized Dr Natalie., I’m having thus strange spikes from being in NSR and HR in the 70’s. to 120 and back continuing on and with the
I’m hoping you remember my past posts I’ve been on a series of meditation trials - is what I’ll call them After my four ablations last one from the highly recognized Dr Natalie., I’m having thus strange spikes from being in NSR and HR in the 70’s. to 120 and back continuing on and with the
Tantaanna
in
AF Association
1 year ago
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