Experiences with

Arimidex

After 11 months on Ibrance and Arimidex has stopped working. It came as a big shock as I feel the best I’ve felt since I was diagnosed in Feb 2021. I was HR +/HER2 - bone only with extensive bone Mets.

Been on Ibrance and Arimidex for 30 cycles for lung metastasis found in May of 2019. I will see oncologist next Tuesday to hear his opinion. Not sure whether to freak or be settled that no activity seen on scan. Opinions?

(now in Liver & bones as my arimidex stopped working) My head is spinning and trying to get info on Kisquali vs. Ibrance combo w/ Faslodex. Just want to make the most of everything and be my own best advocate. Any advice or experiences to share would be most appreciated.

None of my docs understand how my estradiol remains highly elevated (above 100), My T is next to zero, I am lean, DHT in the normal range, taking 3 mg of Arimidex for several months. The estradiol was never checked until after my PSA began to rise after several month of successful BAT therapy.

Prior therapies included: - Arimidex for 5 years prior to progression and MBC diagnosis - iBrance/Faslodex for 2 years - Talzenna for the past year which now seems to be losing its effectiveness. We’re wondering if Letrozole monotherapy might be an option.

The doc and I are scratching our heads over the failure a high dose (4g/day) of arimidex to reduce estradiol below 150. I took my last T injection November 1 when my PSA jumped to 9 and then to 12.5 December 1.

He did switch me from Arimidex to Letrozole because of the absolute fatigue and pain. He said sometimes women respond better to one than the other. I’m just 🤷🏽‍♀️🤷🏽‍♀️🤷🏽‍♀️ Second part of scan in comments.

I'm on Ibrance and Arimidex. About 6 months ago my eyesight got cloudy and blurry. It is not painful, but annoying. I can drive safely, but I have to concentrate. I have seen my optometrist and after an eye exam he said "you are just getting older." (Really!)

I am on Ibrance 75 and arimidex. 75 because of low wbc. I had radiation to a spot on spine so I could continue to ride/train horses. [u]Question[/u]: I'm reading about so many of you who have been on treatments successfully for 5, 10, 15 and more years.

I’m currently taking Ibrance, & Arimidex. I just want to scream!!

Stopped taking arimidex and fulvestrant and was put on Ibrance and Tamoxifen. Had another endoscopy two days ago and the doctor said there is absolutely no sign of any cancer there at all and it was pervasive initially. I am absolutely stunned and so grateful!!!

I’ve been on Arimidex for 4 years with Xgeva shots every 3 months since dx Mbc in January 2017. My tumor markers have increased by about 10 a month so I’m now at 121.

I’m on Ibrance and Anastrozole ( Arimidex). I would like to get the gray out and do some highlights but thinking that might be too much for my hair. Does anyone get their hair done or should I avoid it? It would make me feel better but worry I might lose more hair.

When I was first diagnosed with breast cancer in 1997 I had Tamoxifen for 5 years- the next time 2007, it was Tamoxifen but switched to Arimidex for 5 years, then 2016 it was Letrozole but will this be for 5 or 10 years, as some people say they are on it for 10 years and as I am coming up to 5 years

I know both arimidex and Letrozole are similar but it seems there are more people on this site that are on Letrozole. Any thoughts would be greatly appreciated. I’m 71 and my Onc recently described me as A symptomatic lol I used to feel like 90 but I think I’ve learned to live with arimidex

We started measuring estradiol (thanks to Friedman's book) a month or so into BAT and it came in at an astounding 200, and then started with 1mg arimidex/day and that got it down to 180, lol. Upped it to 2 for a couple months and now is at 100. (Normal is 15-30) .

After my recurrence, I had a mastectomy followed with Ibrance and Arimidex. Took both of year and a half. I tolerated it ok, but never felt myself. Joints affected, foggy brain, hot flashes, hair thinning etc.

Those of us believers here like Patrick, and myself like to keep the E2 about 20 or just under, and this can be accomplished with 1-2 mgs of Arimidex per week. As T can aromatize to E2. And E2 is another Androgen that Pca cells like.

March-dec 2018 - arimidex - progression Line 2. Dec 2018 ibrance /faslo/zometa Have just had small progression of existing mets (more suv uptake on pet/ct scans ) In addition - MRI a month ago showed progression of epidural tumor in my T4-T6 spine.

Breast tumor removed in 2016 followed by radiology & drugs (Arimidex). Fractured wrist Thanksgiving. 2019, then foot last month. Bone scan diagnosed Osteopenia so started Zometa infusion today.