Experiences with

Aranesp

Hi everyone, I've been taking Aranesp injections for 2 years for severe anemia due to myelofibrosis/ET and also side effects of hydroxy. The Aranesp stopped working, and I've been taking luspatercept injections for the last 9 weeks.

I have been on Ibrutinib for 4 months now and more recently (6weeks) on weekly injections of Aranesp because of low red blood count (78). I have also gained 10 pounds in a short period of time. Doctors have changed my diuretic, ruled out blood clots and ruled out heart-related problems.

NJ has served as an expert for the defence attorneys in litigation involving Ferrirprox and Aranesp, and for the plaintiffs' attorneys in litigation involving Neratinib, Loestrin 24 Fe, Suboxone, Doryx, Zoloft, Prozac, Lipitor, and Granuflo. All other authors declare no competing interests.

M D Anderson gave me a shot of Aranesp yesterday but have not seen the OncolOgist your thoughts or experiences ?

His hgb is drifting down -his haematologist does not think it’s caused by the Ruxolitinib but due to disease progression ( white cells are drifting up and platelets drifting down) He gets very tired and sometimes a little breathless so he’s begun a four week course of Aranesp.

dose of ruxoltinib ( Jakafi) back to 15 mg bd ( it had been increased to 20mg bd from the new year, and that increase made me gain another 5kg in weight ( gaind that Instarts on rux - most people do, I was told ) and made me even more tired.) and inceasing the frequency of the epo injections ( Aranesp

My oncologist gave me a shot of Aranesp during my last visit. My HGB had dropped to 8.6 and the RBC to 2.52. Has anyone else been given this medication? Like most drugs, there is a long list of side effect for Aranesp including heart issues.

Yesterday my labs showed HCT at 28, so nephrologist wants to start Aranesp. I know that it will most likely give me more energy, but the black box warning is worrisome. Anyone had issues with blood clots from it?

I take iron tablets and Aranesp injections to increase my Hb levels. I’m waiting for Addenbrookes to get back to me next week, but just wondered if this had happened to anyone else. Any comments and advice will be gratefully appreciated, Thanks Jill

I have my first one tomorrow morning, just looking at what to expect. I had been sitting at 10.0 - 10.1 hgb and 30.4 ish hct for over a year - but today I was at 9.6hgb and 28.8 hct - so they sent my iron levels off, and if they come back good (which they should, I finished iron infusions not too long