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My brother has advanced prostate cancer
Hi everyone. I hope all of you are doing well. My brother diagnosed Aug 2022 with stage 4 prostate cancer at age 53. PSA was 44 and he had some mets in his bones(Pelvic). After that he had triplet therapy(every 3 month hormone therapy+ Docetaxol+ Nubeqa), but unfortunately his PSA rising right after
Hi everyone. I hope all of you are doing well. My brother diagnosed Aug 2022 with stage 4 prostate cancer at age 53. PSA was 44 and he had some mets in his bones(Pelvic). After that he had triplet therapy(every 3 month hormone therapy+ Docetaxol+ Nubeqa), but unfortunately his PSA rising right after
rasher1
in
Advanced Prostate Cancer
11 months ago
Xgeva side effects?????
I started ADT a little over a year ago. I'm on Trelstar and my PSA is < 0.04. In March of this year I started taking Erleada. The side effects from both drugs have been minimal, some hot flashes and fatigue. Two months ago my doctor started me on Xgeva. The first dose I felt no ill effects, but
I started ADT a little over a year ago. I'm on Trelstar and my PSA is < 0.04. In March of this year I started taking Erleada. The side effects from both drugs have been minimal, some hot flashes and fatigue. Two months ago my doctor started me on Xgeva. The first dose I felt no ill effects, but
MydogisTed
in
Advanced Prostate Cancer
11 months ago
SBRT to Prostate and Lymph node ?
Hi All, My Father was diagnosed as stage 4 PCa with widespread bone mets in Nov 2021. Since then he has been on ADT + Enza + Denosumab regimen (details on my profile) His PSA had increased slightly in the last few readings but he has largely been asymptomatic 12/22 - 0.81 03/23 - 0.83 06/23 -
Hi All, My Father was diagnosed as stage 4 PCa with widespread bone mets in Nov 2021. Since then he has been on ADT + Enza + Denosumab regimen (details on my profile) His PSA had increased slightly in the last few readings but he has largely been asymptomatic 12/22 - 0.81 03/23 - 0.83 06/23 -
dudubaya
in
Advanced Prostate Cancer
11 months ago
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TRT anyone?
I was Dx Gleason 8 (4+4) 2015 at 70 years old; had IMRT (25 sessions) & seeds early 2016; shortly after PSA went to .44, but progressively increased to 1.95 by Jan 16 2018; then started dropping: Feb 26 was 1.3, Apr 2 was 1.18, then July 2 it dropped to 0.83. by 11/29/19 0.11 PSA 6/2/20 0.06 8/31
I was Dx Gleason 8 (4+4) 2015 at 70 years old; had IMRT (25 sessions) & seeds early 2016; shortly after PSA went to .44, but progressively increased to 1.95 by Jan 16 2018; then started dropping: Feb 26 was 1.3, Apr 2 was 1.18, then July 2 it dropped to 0.83. by 11/29/19 0.11 PSA 6/2/20 0.06 8/31
900312611
in
Advanced Prostate Cancer
11 months ago
Metastatic PC
First diagnosed in 2017 with high grade PCand put on hormone therapy until Nov. 2019. At that time I had 28 radiation treatments and PSA dropped to 0.05. No therapy from Jan 2023 and ongoing. PSA started rising in early 2023 from 0.05, 0.08, 0.66, to 2.8 in June 2023. PSMA Pet scan shows the cancer
First diagnosed in 2017 with high grade PCand put on hormone therapy until Nov. 2019. At that time I had 28 radiation treatments and PSA dropped to 0.05. No therapy from Jan 2023 and ongoing. PSA started rising in early 2023 from 0.05, 0.08, 0.66, to 2.8 in June 2023. PSMA Pet scan shows the cancer
saniku
in
Advanced Prostate Cancer
11 months ago
Weight LOSS on ADT
Hey all. I was diagnosed with PCa Oct. 2018. After radiation, Zytiga and Lupron, my PSA dropped to no-detect, where it has stayed for the past 3+ years. All very good news, right? Yes....mostly. Though I've dealt with continuing hot flashes and fatigue, my big concern right now is weight loss. I'm normally
Hey all. I was diagnosed with PCa Oct. 2018. After radiation, Zytiga and Lupron, my PSA dropped to no-detect, where it has stayed for the past 3+ years. All very good news, right? Yes....mostly. Though I've dealt with continuing hot flashes and fatigue, my big concern right now is weight loss. I'm normally
LessPaul
in
Advanced Prostate Cancer
11 months ago
aumento de PSA con Abiraterona + Prednisona + docetaxel .
Comence el tratamiento en Marzo/abril de 2022, con seis sesiones de docetaxel, y con abiraterona + prednisone todos los días. Además cada 6 meses decapeptyl. El PSA bajo a 0,1, meses después Marzo 23 subió a 0,5 en Mayo subió a 0,9 y hoy ha subido a 0.28. Desconozco cual es la evolución normal , rogaría
Comence el tratamiento en Marzo/abril de 2022, con seis sesiones de docetaxel, y con abiraterona + prednisone todos los días. Además cada 6 meses decapeptyl. El PSA bajo a 0,1, meses después Marzo 23 subió a 0,5 en Mayo subió a 0,9 y hoy ha subido a 0.28. Desconozco cual es la evolución normal , rogaría
Jerojj
in
Advanced Prostate Cancer
11 months ago
How long should I continue with bicalutamide after radiotherapy?
I just completed 40 external beam IMRT treatments two weeks ago. I was Gleason 3 +4, negative bone and CT scans, and although my Decipher score was a disappointing 68, it forecast that with radiotherapy I have a 9% chance of metastasis in 10 years and a 12% chance of mortality in 15 years. Now age
I just completed 40 external beam IMRT treatments two weeks ago. I was Gleason 3 +4, negative bone and CT scans, and although my Decipher score was a disappointing 68, it forecast that with radiotherapy I have a 9% chance of metastasis in 10 years and a 12% chance of mortality in 15 years. Now age
Smarks42
in
Prostate Cancer Network
11 months ago
treatment and insurance questions
gleason 4+3=7 (70% pattern 4) involving one core less than 0.5mm. PSA 5.2. Biopsy results confirmed by MRI. I am 64 years old and will be 65 in December. I have horrible insurance with very limited treatment options. I would like to delay treatment until I have Medicare (5 months). I have met with
gleason 4+3=7 (70% pattern 4) involving one core less than 0.5mm. PSA 5.2. Biopsy results confirmed by MRI. I am 64 years old and will be 65 in December. I have horrible insurance with very limited treatment options. I would like to delay treatment until I have Medicare (5 months). I have met with
Hidden
in
Prostate Cancer And Gay Men
11 months ago
bacterial infections
hello everyone. First i m happy to join this forum full on nice and precous persons. Im doing hyrimoz 40 mg every two weeks. The PSa is under control. My back that i s my problem its more flexible and no big pain. Lets arrive to the sides effects. Unfortunatly im going every month in problems with
hello everyone. First i m happy to join this forum full on nice and precous persons. Im doing hyrimoz 40 mg every two weeks. The PSa is under control. My back that i s my problem its more flexible and no big pain. Lets arrive to the sides effects. Unfortunatly im going every month in problems with
Jack72
in
NRAS
11 months ago
Darolutimide as monotherapy
I know there has been a phase 2 trial (EORTC-GUCG 1532 trial) testing the efficacy of Darolutimide as monotherapy and was wondering if anyone outside of the trial has done this. The phase 2 triall seemed to show that it could be very effective in lowering PSA. Since it doesn't actually stop testosterone
I know there has been a phase 2 trial (EORTC-GUCG 1532 trial) testing the efficacy of Darolutimide as monotherapy and was wondering if anyone outside of the trial has done this. The phase 2 triall seemed to show that it could be very effective in lowering PSA. Since it doesn't actually stop testosterone
RugbyVLS
in
Advanced Prostate Cancer
11 months ago
On vacation!
Didn't think I would ever go on an ADT vacation. My new urologist thinks it would be a good idea since I have several SE from my MDS-RS with the worst being fatigue added to my ADT fatigue. Have been on Eligard after radiation for 3 yrs. with PSA undetectable. Am sure in my mind that the radiation
Didn't think I would ever go on an ADT vacation. My new urologist thinks it would be a good idea since I have several SE from my MDS-RS with the worst being fatigue added to my ADT fatigue. Have been on Eligard after radiation for 3 yrs. with PSA undetectable. Am sure in my mind that the radiation
SpencerBoy11
in
Advanced Prostate Cancer
11 months ago
Anomaly PSA jump of more than 25%?
Have any of you had a PSA jump (NOT 'bounce' following treatment) that was NOT a sign of recurrence after later having a PSMA-PET to verify? I am not happy with husband's doctor as I pushed to have PSMA-PET done after this jump (before this last PSA there was 6 years of stable PSA following RT w/o ADT
Have any of you had a PSA jump (NOT 'bounce' following treatment) that was NOT a sign of recurrence after later having a PSMA-PET to verify? I am not happy with husband's doctor as I pushed to have PSMA-PET done after this jump (before this last PSA there was 6 years of stable PSA following RT w/o ADT
Researcher50
in
Prostate Cancer Network
11 months ago
Alive at Five
Dx Stage IV metastatic PCa with distant metastices to bones and para-aortic lymph node string on July 2, 2018. Still HS and on a year + medication holiday, PSA undetectable. Initially told I had 18 months to live! 🙏
Dx Stage IV metastatic PCa with distant metastices to bones and para-aortic lymph node string on July 2, 2018. Still HS and on a year + medication holiday, PSA undetectable. Initially told I had 18 months to live! 🙏
6357axbz
in
Advanced Prostate Cancer
11 months ago
Docetaxel Update
Hi Gents, I assume this is SOC. I always have a blood draw one day prior to my chemo infusion. Prior to starting Docetaxel, my PSA was 23.6; after 3 rounds, my PSA is 10.7; a decline of 12.9! Yes, the SE are BAD. I have lost all of my hair. My fingernails are discolored, lifting off and sore. I have
Hi Gents, I assume this is SOC. I always have a blood draw one day prior to my chemo infusion. Prior to starting Docetaxel, my PSA was 23.6; after 3 rounds, my PSA is 10.7; a decline of 12.9! Yes, the SE are BAD. I have lost all of my hair. My fingernails are discolored, lifting off and sore. I have
MJCA
in
Advanced Prostate Cancer
11 months ago
Dose titration for CRPC
Hi For those of us who question why we should recieve the Maximum Tolerated Dose as opposed to a Minimum Effective Dose, the work of the Moffitt among others is of great interest. In the following paper upward dose titration is of particular interest to me as I try to workout how to navigate my CRPC
Hi For those of us who question why we should recieve the Maximum Tolerated Dose as opposed to a Minimum Effective Dose, the work of the Moffitt among others is of great interest. In the following paper upward dose titration is of particular interest to me as I try to workout how to navigate my CRPC
Rickytarr
in
Fight Prostate Cancer
11 months ago
Lupron only after 4.5+ years
I was diagnosed with multiple Mets in August 2018. Started Lupron Nov. 2018. Over the years PSA has bounced up and down from low of 0.5 in March 2021 to high of 1.4 in June 2020. Mostly stayed 0.6 to 0.9. Ended 2022 at .67, but last two readings were 1.01 in March and .98 two days ago. Never had RP,
I was diagnosed with multiple Mets in August 2018. Started Lupron Nov. 2018. Over the years PSA has bounced up and down from low of 0.5 in March 2021 to high of 1.4 in June 2020. Mostly stayed 0.6 to 0.9. Ended 2022 at .67, but last two readings were 1.01 in March and .98 two days ago. Never had RP,
dhccpa
in
Advanced Prostate Cancer
11 months ago
Oncologist and prostate surgeon conflicting treatment
Dad 73yrs has recurrent PC. 5 pelvic lymph nodes with hormone sensitive PC detected via rising PSA after 1.5yrs at undetectable then psma scan confirmed it was now in pelvic lymph nodes. He had his prostate removed a few years before, negative margins and just unlucky. In September last year Oncologist
Dad 73yrs has recurrent PC. 5 pelvic lymph nodes with hormone sensitive PC detected via rising PSA after 1.5yrs at undetectable then psma scan confirmed it was now in pelvic lymph nodes. He had his prostate removed a few years before, negative margins and just unlucky. In September last year Oncologist
Jbooopin
in
Advanced Prostate Cancer
11 months ago
Are PSMA negative mets usually castrate resistant?
I had 2 clear PSMA-PETs (at a PSA of 2 & then 4) so Dr. Scholz recommended I get an FDG PET. Low and behold 3 decent sized mets showed up. In my subsequent research it seems like all the published articles describe the PSMA negative mets as being castrate resistant. Zytiga/Lupron was effective before
I had 2 clear PSMA-PETs (at a PSA of 2 & then 4) so Dr. Scholz recommended I get an FDG PET. Low and behold 3 decent sized mets showed up. In my subsequent research it seems like all the published articles describe the PSMA negative mets as being castrate resistant. Zytiga/Lupron was effective before
V10fanatic
in
Advanced Prostate Cancer
11 months ago
Value of LDH
I've been dealing with PCA 11 years and I've seen a number of doctors along the way but never have discussed or had my LDH tested. A young oncologist where I had my PSMA scan requested PSA, testosterone and LDH tests to go along with the scan. My LDH was at the low end of the "range" (but we still didn't
I've been dealing with PCA 11 years and I've seen a number of doctors along the way but never have discussed or had my LDH tested. A young oncologist where I had my PSMA scan requested PSA, testosterone and LDH tests to go along with the scan. My LDH was at the low end of the "range" (but we still didn't
fourputt
in
Advanced Prostate Cancer
11 months ago
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