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"...results challenge the dogma that treatment with LT4 for hypothyroidism restores TH homeostasis in all patients."
Thyroid hormone homeostasis in levothyroxine-treated patients: Findings from ELSA-Brasil Gustavo C Penna 1 2, Isabela M Bensenor 3, Antonio C Bianco 1, Matthew D Ettleson 1 Affiliations expand PMID: 38506164 DOI: 10.1210/clinem/dgae139 Abstract Context: The effectiveness of levothyroxine (LT4) in
Thyroid hormone homeostasis in levothyroxine-treated patients: Findings from ELSA-Brasil Gustavo C Penna 1 2, Isabela M Bensenor 3, Antonio C Bianco 1, Matthew D Ettleson 1 Affiliations expand PMID: 38506164 DOI: 10.1210/clinem/dgae139 Abstract Context: The effectiveness of levothyroxine (LT4) in
Yostie
in
Thyroid UK
3 months ago
Levo Brands/NICE guidelines
TT two years’ ago from being hypER with goitre. Now on 125mgs Accord Levo. Various ‘symptoms’ but apart from weight gain my main concerns are breathlessness/balance issues/food sensitivities. An interesting consult with my gp this morning and I would like to see what comments the forum might
TT two years’ ago from being hypER with goitre. Now on 125mgs Accord Levo. Various ‘symptoms’ but apart from weight gain my main concerns are breathlessness/balance issues/food sensitivities. An interesting consult with my gp this morning and I would like to see what comments the forum might
C1949K
in
Thyroid UK
2 months ago
Switching from Levothyroxine to Liothyronine
Hello, I hope everyone is well. I haven’t written on here for a while as I’ve been feeling quite well so hope you don’t mind me coming back to you now. Although I feel good on my current dose of thyroxine and definitely don’t feel I’m taking too much, my endocrinologist wants to lower my thyroxine
Hello, I hope everyone is well. I haven’t written on here for a while as I’ve been feeling quite well so hope you don’t mind me coming back to you now. Although I feel good on my current dose of thyroxine and definitely don’t feel I’m taking too much, my endocrinologist wants to lower my thyroxine
Cathrd
in
Thyroid UK
2 months ago
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Some help please with latest thyroid results.
Hi everyone, hope everyone is having a nice day. A snippet of my story. I am a bad converter T4 to T3. Endo put me on T3 as my T4 was showing over range and my T3 just scrapping in at the bottom. he told me to half T4 from 100 to 50 and take 10 of T3. I was not good on this dose my hypothyroid symptoms
Hi everyone, hope everyone is having a nice day. A snippet of my story. I am a bad converter T4 to T3. Endo put me on T3 as my T4 was showing over range and my T3 just scrapping in at the bottom. he told me to half T4 from 100 to 50 and take 10 of T3. I was not good on this dose my hypothyroid symptoms
Katherine1234
in
Thyroid UK
2 months ago
Genetic Testing for cholesterol and insurance
Hi The only test I have outstanding is a genetic test for familial hypercholeserolmia (high cholesterol) . I was told that insurers shouldn’t ask for genetic testing but looking into it FH is considered to be an illness and diagnostic tests can be disclosed. I know travel insurance companies are funny
Hi The only test I have outstanding is a genetic test for familial hypercholeserolmia (high cholesterol) . I was told that insurers shouldn’t ask for genetic testing but looking into it FH is considered to be an illness and diagnostic tests can be disclosed. I know travel insurance companies are funny
Coffeelover2
in
British Heart Foundation
6 months ago
Results and Advice Please
Hi There All, Seeking some expertise please. These are my latest test results taken via Medichecks (finger prick) February 19th; TSH 0.013 mIU/L (0.27 - 4.2) -6.5% Free T4 (fT4) 5.9 pmol/L (12 - 22) -61.0% Free T3 (fT3) 5.7 pmol/L (3.1 - 6.8) 70.3% T4:T3 Ratio 1.035 Thyroglobulin Antibodies (
Hi There All, Seeking some expertise please. These are my latest test results taken via Medichecks (finger prick) February 19th; TSH 0.013 mIU/L (0.27 - 4.2) -6.5% Free T4 (fT4) 5.9 pmol/L (12 - 22) -61.0% Free T3 (fT3) 5.7 pmol/L (3.1 - 6.8) 70.3% T4:T3 Ratio 1.035 Thyroglobulin Antibodies (
CDN_Lady
in
Thyroid UK
4 months ago
Thyroglobulin antibodies test
I tested for thyroid markers recently.I was already diagnosed last summer with hypothyroidism and am medicated with Levothyroxine, so the values of TSH T4 are now in the control range with T3 low borderline. However, anti Tg came positive at 570IU/ml which I understands suggests autoimmune underlying
I tested for thyroid markers recently.I was already diagnosed last summer with hypothyroidism and am medicated with Levothyroxine, so the values of TSH T4 are now in the control range with T3 low borderline. However, anti Tg came positive at 570IU/ml which I understands suggests autoimmune underlying
Pray4health
in
Thyroid UK
3 months ago
Latest test after 4 months on T3
I just wanted to check in as my endo has scheduled an 'urgent' call with me after seeing these results. Should I be worried? TIA all you beautiful people! TSH X <0.005 mIU/L (Range: 0.27 - 4.2) Free T3 5.3 pmol/L (Range: 3.1 - 6.8) Free Thyroxine 18.3 pmol/L (Range: 12 - 22) Thyroglobulin Antibodies
I just wanted to check in as my endo has scheduled an 'urgent' call with me after seeing these results. Should I be worried? TIA all you beautiful people! TSH X <0.005 mIU/L (Range: 0.27 - 4.2) Free T3 5.3 pmol/L (Range: 3.1 - 6.8) Free Thyroxine 18.3 pmol/L (Range: 12 - 22) Thyroglobulin Antibodies
wavedancers
in
Thyroid UK
4 months ago
GAZYVA & VENCLEXTA…I thought it wasn’t working. Apparently it was, extremely well
Had PET scan yesterday, read the report today. I haven’t spoken to my Doc yet. But according to this report there are no signs of enlarged lymph nodes anywhere. Kind of blows my mind, the main reason I started treatment was because of my abdominal pain (which I still have). I am considered high risk
Had PET scan yesterday, read the report today. I haven’t spoken to my Doc yet. But according to this report there are no signs of enlarged lymph nodes anywhere. Kind of blows my mind, the main reason I started treatment was because of my abdominal pain (which I still have). I am considered high risk
Corgidad
in
CLL Support
6 months ago
Blood test
Hi Sorry for being a pest but I'm completely drained and brain fog preventing memory , GP stopped my T3 I advised her to increase my T4 ( I don't convert ) accordingly, she queried why I would need an increase ( I query is she qualified) I explained why ( she was clueless ) anyway she's ordered a full
Hi Sorry for being a pest but I'm completely drained and brain fog preventing memory , GP stopped my T3 I advised her to increase my T4 ( I don't convert ) accordingly, she queried why I would need an increase ( I query is she qualified) I explained why ( she was clueless ) anyway she's ordered a full
Jodiedebs
in
Thyroid UK
5 months ago
Latest results, I’m a bit confused
Fresh in today, and I’m amazed at the B12 result! My B12 has been steadily dropping, the last test in March last year showed total B12 at 271 range 145-569, this result is >150 for active B12, there isn’t a result for total but I’m not sure why it’s missing. Can anyone enlighten me? My CRP has shot up
Fresh in today, and I’m amazed at the B12 result! My B12 has been steadily dropping, the last test in March last year showed total B12 at 271 range 145-569, this result is >150 for active B12, there isn’t a result for total but I’m not sure why it’s missing. Can anyone enlighten me? My CRP has shot up
Espeegee
in
Thyroid UK
3 months ago
Monitor My Health iron test - lack of ranges
I spent a bit more money on my MMH test this year as I’ve never had an iron panel done but have always had low iron indicators on a full blood test. I didn’t get complete results as ferritin failed (posting the kit back took 48 hours when it was tracked to take 24) but the results I did get, I can’
I spent a bit more money on my MMH test this year as I’ve never had an iron panel done but have always had low iron indicators on a full blood test. I didn’t get complete results as ferritin failed (posting the kit back took 48 hours when it was tracked to take 24) but the results I did get, I can’
Bearo
in
Thyroid UK
4 months ago
How to approach GP to get private endocrinologist referral?
Hello, I'm after a bit of advice really. I have approached a private endocrinologist who has come recommended by someone in this forum, but this endo says that they need a GP referral before they can make an appointment. I'm not sure how to pitch my request to my GP? My TSH is good however my T3 and
Hello, I'm after a bit of advice really. I have approached a private endocrinologist who has come recommended by someone in this forum, but this endo says that they need a GP referral before they can make an appointment. I'm not sure how to pitch my request to my GP? My TSH is good however my T3 and
Auntbessy
in
Thyroid UK
3 months ago
Tight chest/ache but peak flow about the same
Good morning, I am looking for advise for my 16 year old daughter please. She has had asthma since she was 2 years old. For years she was using Clenil ( Quvar 50 in lockdown) and used Ventolins. In Jan and Feb of this years she had a couple of mild asthma attacks which normally could be controlled
Good morning, I am looking for advise for my 16 year old daughter please. She has had asthma since she was 2 years old. For years she was using Clenil ( Quvar 50 in lockdown) and used Ventolins. In Jan and Feb of this years she had a couple of mild asthma attacks which normally could be controlled
Fraggle1234
in
Asthma Community Forum
1 month ago
16 week mid wife appointments ( outpatient)
I went for my appointment today , I’m giving birth not at my local hospital due to me choosing a much better hospital and receiving misdiagnosis which has caused lots of issues Anyway this appointment today she was late , didn’t know what she was doing , couldn’t use the printer etc , told me not sure
I went for my appointment today , I’m giving birth not at my local hospital due to me choosing a much better hospital and receiving misdiagnosis which has caused lots of issues Anyway this appointment today she was late , didn’t know what she was doing , couldn’t use the printer etc , told me not sure
Jade2006
in
Pregnancy and Parenting Support
6 months ago
thyroid results
hi there please can someone help me understand my results from a recent thyroid function test: tSH levels were 4.63 mu/L which indicates it’s high Thyroxine levels were 13.3 pmol/L and it’s saying that’s normal Triiodothyronine levels 4.4pmol/L levels normal The indication is that I don’t need treatment
hi there please can someone help me understand my results from a recent thyroid function test: tSH levels were 4.63 mu/L which indicates it’s high Thyroxine levels were 13.3 pmol/L and it’s saying that’s normal Triiodothyronine levels 4.4pmol/L levels normal The indication is that I don’t need treatment
CasaRitchin
in
Thyroid UK
3 months ago
Vitamin/mineral deficiencies
Hi. I've had Pbc for 6 yrs now. Recently I've noticed that I am more fatigued than normal. I asked for my blood results over the last 10 yrs . I noticed a progressive decline in my ferritin levels over the last few yes. I had a vitamin b12 level done recently and it was just above the borderline/normal
Hi. I've had Pbc for 6 yrs now. Recently I've noticed that I am more fatigued than normal. I asked for my blood results over the last 10 yrs . I noticed a progressive decline in my ferritin levels over the last few yes. I had a vitamin b12 level done recently and it was just above the borderline/normal
Finn2021
in
PBC Foundation
6 months ago
Grandaughter just diagnosed with PCOS
Hello my granddaughter (27) has just been diagnosed with PCOS. She had the results of blood test yesterday which showed LH level abnormal (5.7 iu/l) FSH level low 3.1 iu/L Prolactin High (262) MiU/L Testosterone High 4.0 nmol/L Sex Hormone binding High 43.7 nmol/L US Pelvis Left pelvic pain, dysmenorrhoea
Hello my granddaughter (27) has just been diagnosed with PCOS. She had the results of blood test yesterday which showed LH level abnormal (5.7 iu/l) FSH level low 3.1 iu/L Prolactin High (262) MiU/L Testosterone High 4.0 nmol/L Sex Hormone binding High 43.7 nmol/L US Pelvis Left pelvic pain, dysmenorrhoea
Daisydarling
in
PCOS UK (Verity)
3 months ago
help - started oestrogel- 4th day - but does it lower thyroid ? My stomach motility stopped again
hi wonderful people I started HRT oestrogel and 4th day and 2 pumps - I have really bad bloating and zero stomach motility - Does it interfere with thyroid t4 or t3 ? I have read it can lower thyroid or block the cell ? When stomaxh motility is so bad I can’t eat properly and weight is low but can
hi wonderful people I started HRT oestrogel and 4th day and 2 pumps - I have really bad bloating and zero stomach motility - Does it interfere with thyroid t4 or t3 ? I have read it can lower thyroid or block the cell ? When stomaxh motility is so bad I can’t eat properly and weight is low but can
Chouchou1234
in
Thyroid UK
6 months ago
Help Needed! Have I got Pernicious Anaemia?
I hope this isn't too long and/or too boring. I suspect I have PA but as with a lot of people here, no-one seems to take B12 deficiency seriously. I also have hypothyroidism so as my symptoms got increasingly worse over the past few years, I blamed my thyroid - the two conditions have many symptoms
I hope this isn't too long and/or too boring. I suspect I have PA but as with a lot of people here, no-one seems to take B12 deficiency seriously. I also have hypothyroidism so as my symptoms got increasingly worse over the past few years, I blamed my thyroid - the two conditions have many symptoms
Grannypants
in
Pernicious Anaemia Society
4 months ago
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