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225ACPSMA617 vs LU177PSMA vs DOCETAXAL(or any other chemo) all of these after failing abiraterone
Abiraterone
failed psa 3.30.
Abiraterone
failed psa 3.30.
Nirman
in
Advanced Prostate Cancer
3 years ago
Cyclophosphamide for mCRPC???
Hello everyone, I had once consulted an oncologist who suggested that my father could try oral cyclophosphamide (metronomic therapy) when
abiraterone
fails.
Hello everyone, I had once consulted an oncologist who suggested that my father could try oral cyclophosphamide (metronomic therapy) when
abiraterone
fails.
Vsahay
in
Advanced Prostate Cancer
3 years ago
Medication shortage
I have been on
Abiraterone
(Zytiga) with prednisone since September 2020 provided by BioPlus delivered by FedEx out of Florida. My residence is in South Carolina.
I have been on
Abiraterone
(Zytiga) with prednisone since September 2020 provided by BioPlus delivered by FedEx out of Florida. My residence is in South Carolina.
PeteLG
in
Advanced Prostate Cancer
3 years ago
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Docetaxal survivors
Hello I need some positive stories of metastatic prostate cancer who has docetaxal chemo after
abiraterone
stopped working.... anybody? To boost morale
Hello I need some positive stories of metastatic prostate cancer who has docetaxal chemo after
abiraterone
stopped working.... anybody? To boost morale
Nirman
in
Advanced Prostate Cancer
3 years ago
By chance anyone got success with Enzalutamide after abiraterone ?
Stage 4 metastatic with several bone mets For my Dad
abiraterone
worked like 3 years which I consider good response but I just want to know by chance if someone got success with xtandi after
abiraterone
stopped working ?
Stage 4 metastatic with several bone mets For my Dad
abiraterone
worked like 3 years which I consider good response but I just want to know by chance if someone got success with xtandi after
abiraterone
stopped working ?
Nirman
in
Advanced Prostate Cancer
3 years ago
orchiectomy Yes or No?
My fasther is on 12 weekly triptorelin injections on last 4 years now
abiraterone
stopped working already started steroid switch few days ago, now doctor suggested for orchiectomy if somebody with knowledge shares goods and bads of orchiectomy or if continue with injection treatments?
My fasther is on 12 weekly triptorelin injections on last 4 years now
abiraterone
stopped working already started steroid switch few days ago, now doctor suggested for orchiectomy if somebody with knowledge shares goods and bads of orchiectomy or if continue with injection treatments?
Nirman
in
Advanced Prostate Cancer
3 years ago
NICE not playing nice again.
Lynparza is aimed at adults whose BRCA-positive prostate cancer has progressed after use of the hormone-based chemotherapy drug
abiraterone
or treatment with the nonsteroidal antiandrogen enzalutamide.
Lynparza is aimed at adults whose BRCA-positive prostate cancer has progressed after use of the hormone-based chemotherapy drug
abiraterone
or treatment with the nonsteroidal antiandrogen enzalutamide.
pjoshea13
in
Advanced Prostate Cancer
3 years ago
Bipolar Androgen Therapy vs Enzalutamide in Asymptomatic Men With Castration-Resistant Metastatic Prostate Cancer.
The PSA-PFS for enzalutamide increased from 3.8 months after
abiraterone
to 10.9 months after BAT. The PFS2 for BAT→enzalutamide was 28.2 versus 19.6 months for enzalutamide→BAT (HR, 0.44; 95% CI, 0.22 to 0.88; P = .02).
The PSA-PFS for enzalutamide increased from 3.8 months after
abiraterone
to 10.9 months after BAT. The PFS2 for BAT→enzalutamide was 28.2 versus 19.6 months for enzalutamide→BAT (HR, 0.44; 95% CI, 0.22 to 0.88; P = .02).
Balsam01
in
Advanced Prostate Cancer
3 years ago
Doctor refuses to test for AR-V7
The doctor says that since hubby progressed on both
Abiraterone
and Xtandi the test is useless. I mentioned re-challenge after chemo but he ignored me. Is this worth seeing another doctor for a second opinion? How valuable is testing for AR-V7 after failure of
Abiraterone
and Xtandi?
The doctor says that since hubby progressed on both
Abiraterone
and Xtandi the test is useless. I mentioned re-challenge after chemo but he ignored me. Is this worth seeing another doctor for a second opinion? How valuable is testing for AR-V7 after failure of
Abiraterone
and Xtandi?
WildRose6
in
Advanced Prostate Cancer
3 years ago
Why continue LUPRON when ADT not working?
Then added
Abiraterone
for 8 months. Currently stopping
Abiraterone
and I am having EBRT on femur. In three weeks I begin Radium 223.
Then added
Abiraterone
for 8 months. Currently stopping
Abiraterone
and I am having EBRT on femur. In three weeks I begin Radium 223.
baltha
in
Advanced Prostate Cancer
3 years ago
Need suggestion PSA 878 after one month of 3rd Chemo
I even asked him about starting
abiraterone
acetate he rejected stating it will not work we have PSMA Pet CT tomorrow, and the doctor said may give nuclear on 16 Mar 2021.
I even asked him about starting
abiraterone
acetate he rejected stating it will not work we have PSMA Pet CT tomorrow, and the doctor said may give nuclear on 16 Mar 2021.
Vasanta
in
Advanced Prostate Cancer
3 years ago
Docetaxel vs. Cabazitaxel--effectiveness?
Last year he tried both
Abiraterone
and Xtandi but PSA is still rising, even after docetaxel. MO wants him to try cabazitaxel next. My question is, is there really that much difference in effect on the cancer? If he's progressing after docetaxel what are the chances cabazitaxel will help?
Last year he tried both
Abiraterone
and Xtandi but PSA is still rising, even after docetaxel. MO wants him to try cabazitaxel next. My question is, is there really that much difference in effect on the cancer? If he's progressing after docetaxel what are the chances cabazitaxel will help?
WildRose6
in
Advanced Prostate Cancer
3 years ago
Apalutamide + Abiraterone combo shows good results in Phase III trial
The trial showed a 30% reduction in disease progression or death for people with mCRPC taking the drug combo (22 vs. 16 months) vs. those taking
abiraterone
(Zytiga) alone: https://www.janssen.com/janssen-presents-results-from-phase-3-acis-study-patients-with-metastaticcastration-resistant-prostate-cancer
The trial showed a 30% reduction in disease progression or death for people with mCRPC taking the drug combo (22 vs. 16 months) vs. those taking
abiraterone
(Zytiga) alone: https://www.janssen.com/janssen-presents-results-from-phase-3-acis-study-patients-with-metastaticcastration-resistant-prostate-cancer
curious-mind1
in
Advanced Prostate Cancer
3 years ago
Metformin and Androgen Receptor-Axis-Targeted (ARAT) Agents Induce Two PARP-1-Dependent Cell Death Pathways in Androgen-Sensitive PCa Cells.
This is a cell study, but it provides a rationale for using Metformin with
Abiraterone
/Enzalutamide, i.e. androgen receptor-axis-rargeted (ARAT) agents.
This is a cell study, but it provides a rationale for using Metformin with
Abiraterone
/Enzalutamide, i.e. androgen receptor-axis-rargeted (ARAT) agents.
pjoshea13
in
Advanced Prostate Cancer
3 years ago
Next step!
*NOTE- The patient is asymptomatic and is taking
abiraterone
acetate tablets (1000 mg) with prednisone.
*NOTE- The patient is asymptomatic and is taking
abiraterone
acetate tablets (1000 mg) with prednisone.
Vsahay
in
Advanced Prostate Cancer
3 years ago
Prednisone 5mg twice daily ready to toss the bottle on my road
Abiraterone
only 250mg daily, Lupron 90 Inj's, and Prednisone 5mg/2X/day since Sept 2019. PSA 0.54 Sept 0.80 Dec 2020. Read this please: Why was I so energized from a steroid on my Adv PCa treatment? Had an annual Eye Exam yesterday, complete and comprehensive.
Abiraterone
only 250mg daily, Lupron 90 Inj's, and Prednisone 5mg/2X/day since Sept 2019. PSA 0.54 Sept 0.80 Dec 2020. Read this please: Why was I so energized from a steroid on my Adv PCa treatment? Had an annual Eye Exam yesterday, complete and comprehensive.
depotdoug
in
Advanced Prostate Cancer
3 years ago
Abiraterone stopped working new Psma pet scan shows cancer progression
My father age 71 have been on
abiraterone
and triptorelin injections every three months last 3 years and few months since diagnosed last few months psa was rising slowly 0.03 to 3 in few months doctor suggested for the Psma pet scan and 5-6 bone mets including new meta developed on 8th and 10th Ribs
My father age 71 have been on
abiraterone
and triptorelin injections every three months last 3 years and few months since diagnosed last few months psa was rising slowly 0.03 to 3 in few months doctor suggested for the Psma pet scan and 5-6 bone mets including new meta developed on 8th and 10th Ribs
Nirman
in
Advanced Prostate Cancer
3 years ago
Xtandi effectiveness
Next move if Xtandi doesn't work is
Abiraterone
after his Provenge infusions are over.
Next move if Xtandi doesn't work is
Abiraterone
after his Provenge infusions are over.
GoNapoli
in
Advanced Prostate Cancer
3 years ago
Bone Marrow Failure After 2 Rounds of Ra223
In the past 2 years I have been through
abiraterone
then the ProSTAR trial only enzalutamide which failed quickly and was moved to the arm receiving both enza & CPI-1205...failed quick and removed from trial.
In the past 2 years I have been through
abiraterone
then the ProSTAR trial only enzalutamide which failed quickly and was moved to the arm receiving both enza & CPI-1205...failed quick and removed from trial.
Trengle
in
Advanced Prostate Cancer
3 years ago
No intensification - is doc too laid back?
Should I, despite the benign current markers, persuade doc to go for treatment intensification – PARP inhibitor, chemo+
abiraterone
, or whatever? Is there any reasonable chance of delaying time to castration resistance and new mets by doing this?
Should I, despite the benign current markers, persuade doc to go for treatment intensification – PARP inhibitor, chemo+
abiraterone
, or whatever? Is there any reasonable chance of delaying time to castration resistance and new mets by doing this?
Purple-Bike
in
Advanced Prostate Cancer
3 years ago
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