Taken ibrance / letrozole combo...

[Millymilo99]

Hello, just came across this forum nice to see so many people having good results with ibrance, I am hoping to be the same early days... for me has anyone been on this medicine longer than 5years they say it works for 2 years for metastatic brest cancer..?

[Teddielottie]

I hope you get a good run on this combo ! I have been on it for over 7 years now ( my first line treatment since my secondary breast cancer de novo diagnosis late 2017) , and have tolerated it well . I have even managed to remain on the full 125mg dose , but many ladies do well on the 100 mg or 75mg doses too . I have had side effects but these have diminished over the years . I am 61 and live in the U.K. .

If you have any questions please do get in touch x

[Millymilo99 in reply to Teddielottie]

Thanks for your reply, wow 7years do you mind if I ask you where your mets are I have them in my lymph nodes, most people I see have bone mets on here I am 65 and live in nz not seen anyone else from new Zealand on this site. Take care...

[Nocillo]

I got 2 years

[Aprilfoolz1]

I was on Ibrance and fulvestrant for 5 years and one month . Recently switched to Kisqali / fulvestrant. My Mets were all distant lymph nodes in my chest and my left superclavicle node(s). Ibrance worked great, clear scans after 9 months of ibrance and fulvestrant. I tolerated it well , had 2 dose reductions due to low neutrophils which is pretty common. Recently,(3/24) a spot on my right adrenal gland was noted. Watched for 9 months (3 scans ). It got brighter larger , now is 1cm so oncologist switched me to Kisqali just this month.

[Millymilo99 in reply to Aprilfoolz1]

Hi, thanks for your comment very helpful...

[Aprilfoolz1 in reply to Millymilo99]

I'm now 60, dx stage IV at 55. I have had minimal side effects and have been able to work full time, travel and live a fairly "normal " life. Initially, when first dx I had fatigue and laryngitis from cancer in my superclavical node pressing on my left laryngeal nerve . That cleared up after 5 months of ibrance / fulvestrant. Hope this info helps you feel confident in treatment and you have good results

[awesome4ever]

Hi. Sorry you have been diagnosed with this disease. I got 5 years on Ibrance and Femara and now been on my 2nd line since March of 2023. I wish you many years on this first treatment line. It's a great one. I stayed on the full dose of Ibrance because I had no side effects except low neutrophils ( always maintained to stay above 2 for me). However many people have to lower the dose the dose and that is perfectly fine. It still seems to work perfectly fine. My oncologist always said to stay on the highest dose that you can tolerate as the clinical trials that got FDA approval was on the 125 mg dose. I haven't been on it for awhile so I don't follow any updates. Good luck. You've got this.

[Millymilo99 in reply to awesome4ever]

😃 thanks...

[Red1246]

Was diagnosed in July 2019 with mbc in bones. Original bc in 2008. Have done very well on Ibrance 100 mg and Femara and CT scans have shown no metastasis. 🙏🏻 Many do well with this regime and I hope you will as well.

I’m 78 and have no side effects other than fatigue awaiting WBCs to elevate before starting next cycle. I’m actually on the meds 3 weeks and off 3 due to low neutrophils.

[Millymilo99]

😃