First Trodelvy Infusion

[DorothyR]

I was diagnosed with MBC in December of 2019 de novo.

After 2 years of Verzenio, cancer started to affect the bone marrow. Dr. started Enhertu which cleared the bone marrow and I had no major issues (I had pnemonitis which was cleared) I was on Enhertu for 1 year.Now after PET scan last week I have progression with new spots on bone. (I have bone mets and brain mets)

Dr. Is starting me on Troelvy.

I feel a great deal of apprehension with starting this new drug.

Does anyone have any experience with this medication?

Any advise on side effects?

Thank you,

Dorothy

[Best521]

Hi DorothyR. A few of us have just started this drug. Some have had minimal side effects but others including myself are having a rougher time. This is a highly effective drug and one of the new anti-body drug conjugates oncologists call smart bombs. I am willing to push through if it is effective, the treatments for side effects help and if it gets easier with fine tuning. Please see my earlier post.

[DorothyR in reply to Best521]

Thank you for your response.I'm sorry it is giving you a rough go of it. Hopefully your side effects will lessen as time goes by.

Take care

Dorothy

[Ticket123]

Hello! I recently started this med. some people people sail right through and others not so much. I have had 2 doses and it has been a bit rough. The Nausea has been for hard for me. It tends to last 3 days. My white blood counts tanked so they had to put me on Nulesta to bolster them. My onc says that there is real hope to having it become more manageable. I’m banking on that!!!! Remember everyone responds differently. ❤️

[DorothyR in reply to Ticket123]

Thank you for your response.I hope your side effects become more manageable.

My Onc said he didn't expect me to have a hard time with the meds. But he will be monitoring me.

Take care

Dorothy

[NPmary]

Dorothy, may I ask what you're doing or did for brain Mets (I had cyber surgery for mine). Thanks

[DorothyR]

N Primary,I had Wholee Brain Radiation . I have also.been on Enhertu which does cross the blood brain barrier.

So far the lesions have shrunk or are stable.

Trodelvy will also cross the blood brain barrier.

Best wishes.

Dorothy

[Iwasborntodothis]

Just finished fourth cycle. It started out pretty rough but I'm told it because it works to well and quickly. Please read my posts. This round has been a lot easier or I am better at predicting and dealing with effects. Either way, it is making all of my lab results go the right direction and my oncology team is thrilled. I think these new drugs are truly miracles for all of us. I hope I continue my track record of getting a year out of each therapy (well most of them).

Allison

[DorothyR in reply to Iwasborntodothis]

I'm so happy for you. Being able to predict your side effects is very important for your well being. And getting the results is another positive.

I had 1st cycle today. So far I'm just a little sleepy due to the benadryl.

I wish you Continued success.

Dorothy

[MBorne1 in reply to DorothyR]

I just had my 2nd dose of my first cycle yesterday. I had the Benadryl hangover after coming home and slept for a few hours. But woke up and now can’t get back to sleep due to the steroids. Watching junk tv now. lol

The side effects have been manageable and I don’t feel anything like I did on other chemo regimens. Carbo almost killed me and I had to receive blood and platelet transfusions. I missed multiple treatments with that line. I’m hoping this drug works cuz it’s been working for multiple years for many of my friends with tnbc.