What’s next after Piqray?: Hello ladies... - SHARE Metastatic ...

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What’s next after Piqray?

Adele_Julia profile image
15 Replies

Hello ladies,

I’ve been on Piqray since December of last year - 12/2021 and scans have been stable.

My onc said next in line would be Enhertu but with having only one true functioning lung ( my right lung is trapped due to a botched mastectomy and radiation from 2019), I’m nervous about going through IV chemo again given the side effects of lung inflammation and such.

ladies that have been on Piqray, what are alternative drugs?

Thank you in advance !

Julia

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Adele_Julia profile image
Adele_Julia
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15 Replies
Pbsoup profile image
Pbsoup

What about Xeloda? It works well for many women. There are side effects, but manageable ones and it's an oral chemo treatment not IV

Adele_Julia profile image
Adele_Julia in reply toPbsoup

Thank you ! I’ll ask my oncologist. Blessings Julia

SunShineEveryDay profile image
SunShineEveryDay in reply toAdele_Julia

Sweety I too have heard great things about Xeloda and very well tolerated indeed!!

Google it on the subject on the platform here, some great stories. :)

But you aren’t changing yet right???

Love you!! 🤗

Adele_Julia profile image
Adele_Julia in reply toSunShineEveryDay

No just trying to get information. Still on Piqray

Silver126 profile image
Silver126

Xeloda is a good option, but Enhertu isn’t chemo, it’s immunotherapy, so I would consider it.

Adele_Julia profile image
Adele_Julia in reply toSilver126

That’s odd. Enhertu is being listed as chemotherapy.

Ursula_I profile image
Ursula_I in reply toAdele_Julia

Enhertu is my next line, my onc is really enthusiastic about it, and I don't think it's chemo. It is IV though.

Gailcav profile image
Gailcav

I had to stop Piqray in April because it was causing kidney damage. I have been doing monthly Faslodex injections, and my numbers have been good. After a few denials and appeals, I am having a Pet Scan on October 12th. I will meet with my Oncologist on the 14th for next steps. I'll let you know.

Adele_Julia profile image
Adele_Julia in reply toGailcav

please do !

Silver126 profile image
Silver126

I don’t know… I’m Italy it’s not so… I talked about this treatment with my onc two months ago, but then my biopsy showed I remain Hr+ Her2 0. Let’s see if someone else can help 🤔

8576 profile image
8576

Hi: I am not sure if Piqray is compatible with Verzenio. I am on 10g.0mgs. twice a day with Tamoxifen 5mgs. It has been studied and found that it is just as effective at the lowest dose.

Hope this helps. Verzenio is apparently, a sister drug to Ibrance.

Cheers, June S.

atoth17 profile image
atoth17

I am taking Xeloda after I took Piqray, I am tolerating it quite well, it’s a good drug so far.

Photo-Bug profile image
Photo-Bug

This is what I found online:

Yes, Enhertu (Fam-trastuzumab deruxtecan-nxki) is a chemo drug (chemotherapy) and it is also a targeted therapy anti-cancer drug. Enhertu fights cancer in two ways: the antibody (trastuzumab) part is designed to find and attach to the HER2 receptor on cancer cells.

I was on Xeloda before the Piqray. Except for the hand and foot syndrome, it worked well for me. After the Piqray, I went on IV Taxol. After 12 weeks, my tumor markers had not moved. Now I am on Exemestane. After a couple of months, the tumor markers have not moved. Doc wants me to try Afinitor with the Exemestane but I don't care for the side effects.

I am not sure where you go from here but many blessings for a good journey.

Adele_Julia profile image
Adele_Julia in reply toPhoto-Bug

Thanks so much! Blessings

Rbeth profile image
Rbeth

going on TRUQAP on Monday. Reenie

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