Another interesting study

[Hazelgreen]

ascopubs.org/doi/10.1200/JC...

"Using the Danish Breast Cancer Group and other nationwide databases, we identified women with early or late BC recurrence during 2004-2018, who were alive 6 months after recurrence. We followed them until BC death, death from other causes, emigration, 10 years, or December 31, 2018, whichever came first."

RESULTS

"Among 2,004 patients with late recurrence, 721 died of BC with a median survival time of 10 years (MR = 84.8 per 1,000 PY; 10-year cumulative mortality = 50%). Among 1,528 patients with early recurrence, 1,092 BC deaths occurred with a median survival time of 4 years (MR = 173.9 per 1,000 PY; 10-year cumulative mortality = 72%)."

"Advanced stage at primary diagnosis, distant metastases, adjuvant treatment for locoregional recurrence, and systemic treatment for distant recurrence were associated with increased mortality after late recurrence. Breast-conserving surgery at primary diagnosis, locoregional recurrence, and surgery for recurrence were associated with lower mortality after late recurrence."

CONCLUSION

"Patients with late recurrence had more favorable prognosis than patients with early recurrence. The localization of recurrent disease was the main prognostic factor for BC death."

[Hazelgreen]

Please note the long median survival time for "late recurrance" - 10 years! Half of the women lasted more than 10 years with late recurrence MBC!

[Pbsoup in reply to Hazelgreen]

How is late recurrence defined?

[Hazelgreen in reply to Pbsoup]

In this Danish study, late recurrence was defined as 10 or more years after a BC diagnosis. Please see the link given above.

Regards,

Cindy

[Bettybuckets]

Thanks for sharing!

[Adele_Julia]

Well I got a reoccurrence in a year after my initial diagnosis. I wonder if my surgeon who did the lumpectomy in 2019 did t get the margins after all. I had surgery in 2019 followed by 8’rou da of chemo and another surgery only to have it come back Nov 2020 as MBC to pleura

[RLN-overcomer]

Sister/warrior/advocate thank you for this study information comparing early recurrence, as opposed to late recurrence of breast cancer. Interesting statistics. Thank you 😇