Phase 3 - Emerald Study

[Sunnydrinking]

Hi ladies

I visited Mount Vernon Cancer Centre yesterday here in the UK.

After a discussion and several questions I have now signed up for Phase 3 of the Emerald Study. You can look this up on line if you fancy reading more about it.

It will initially involve quite a few tests including a full body MRI etc. It should eventually revert back to 4 weekly hospital visits.

I could be given the trial drug, Elacestrant or standard of care treatment.

I’m just hoping I’ve made the right decision and all turns out positive and most of all it attacks my liver progression.

Wishing everyone much success in their treatment.

Meanwhile, I’m enjoying life and loving my 8 day old chicks.

Jo x

[Teddielottie]

Wishing you luck as you start on this trial ! We will all be there behind you !

ps . How soon does it start ? Much love x

[Sunnydrinking in reply to Teddielottie]

Hi

I’ve been told to stop Letrozole for the next 2 weeks and then I should be able to start he study, unless of course, any further tests deem me unsuitable...

I’ve been told to expect an appointment for a full body MRI soon.

Incidentally, it’s a random selection process as to whether I’m given the new drug, Elacestrant vs. Standard of care treatment. Just like a toss of a coin - I’ve always enjoyed a little gamble.... but I would prefer to be given the new drug,

I hope I’m doing the right thing.

Jo x

[Teddielottie in reply to Sunnydrinking]

We always hear about trials but very few of us have actually done one , but I can well imagine what is going through your mind !

What is the Standard of care treatment ? Any chance of getting Genome testing with it ?! What does your onc /GP think? Take care but keep busy ! x

[Barbteeth]

Hi Jo

I was offered to take part in a study in January but I wasn’t told a name so not sure if it’s the same or similar to yours...I was too wound up and emotional at the time so declined...difficult decisions...so I chose Afinitor and exemastane which faiked anyway and my liver mets worsened so I now wonder if I should have gone on the trial...but then Covid came along and I think the study was stopped

I’ll look it up as I find it interesting

Pleased your chicks are doing well...Vanessas chickens have settled in although one (Charlotte) is a bit nasty

I’ll put a pic on for you

Good luck

Barb xx

[Hidden]

Hi Jo,

I wish you all the best as you get ready to take part in the study. I hope it proves effective at treating the liver progression and puts a halt on the cancer. Let us know how you get on.

Sophie x

[MacroMom]

Good for you, I hope you get the Elacestrant too! Do you know if they will put you back on Letrozole then or switch to another type of estrogen blocker? It sounds like they will be monitoring you closely either way so they'll know if it's working. Please do keep us posted!

Patty

[Bestbird]

Wishing you excellent results!

[Wintervt]

Hi Jo,

I was going to participate in the EMERALD trial but was excluded as I am not post menopausal. Elacestrant is supposed to be a very promising drug with few side effects. Wishing you all the best.

xo Jade

[MyMiracle13]

If I was offered the opportunity, I would take it too. Alas, we don’t have clinical trials in the Philippines. Wishing you good vibes😄 I do hope you get the Elacestrant.

[Hidden]

Well done you.

Being of a scientific background, I am a firm believer in trials.

What have you got to lose by doing it? Nothing. You either get the normal treatment or a new drug that is in its final testing stage.

You are helping all of us and future mbc patients in participating in this.

I hope you get the new drug too.

Clare x

[hdhonda]

Jo,

I too hope it is very successful. Great results is what we want. Blessings, Hannah

[Valisa]

Wishing you all the best with this trial, fingers crossed you get the new drug and not standard care. Hopefully this brings positive results for you.

[Ntash01]

Hi Sunnydrinking

I go to MV for full body MRIs - I have them every 3 months....such a long process but grateful for them....I keep my eyes shut throughout the whole hour!

Wishing you well and hope you can begin the trial!

N x

[hopenowandtomorrow]

Hoping you get good results from this trial Jo! Looking forward to hearing how it goes for you! All the best! ❤️🙏❤️

[Arisgram]

I, too, have liver progression. I've been given everolimus and letrozole. My local oncologist is less than happy with me saying I should be on faslodex instead of the AI, but because of my needle "issue" the oncologist at MDA gave me letrozole. The local doc said only the everolimus will be effective.

I say this because I believe elacestrant is oral faslodex. I would love to be in your trial, and i wish you the very best!! Everything I read about the new drug sounds promising.

Fingers crossed, Andi

[diamags]

Jo,

The trial sounds very good. I want to say thank you for pursuing it. It was women like you who gave us the advanced drugs we enjoy today. Trials are so very important. Thank you, thank you, thank you!

[hopenowandtomorrow]

Hoping you get good results from this trial Jo! Looking forward to hearing how it goes for you! All the best! ❤️🙏❤️

[AvidBooklover]

Wishing you stellar results! Just went out and read up on this. Love there is something new possible!

[Beryl71]

Good luck, hope it goes well.

[mariootsi]

Jo, All the best in the trial! You are one of the women who could, with your participation, give another option to cancer patients! Amazing.