Buprenorphine and Nausea: Basically I... - Restless Legs Syn...

Restless Legs Syndrome

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Buprenorphine and Nausea

davchar23 profile image
11 Replies

Basically I successfully use buprenorphine (0.4mg/da) to block RLS but the resultant nausea is a serious well known side affect. I have been well guided by many on this site as to how to combat the nausea and have tried many of the suggested solutions except for me the last resort medical cannabis. I am currently using Zofran anti nausea tablets.

I am interested to know from fellow buprenorphine users what form their nausea takes and how they handle it.

For me I am woken between 4-6am with a sickly feeling in my stomach which makes me take several deep breadths to temporarily stop only to repeatedly return and keep me awake. it stops when i get up but as soon as i eat or drink anything i break out into cold sweats which last about 10/15minutes before subsiding to just a stomach discomfit which in turn slowly subsides by noon

I s this similar to many of you?

Regards

Davchar23

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11 Replies
Ticki profile image
Ticki

well I’m not gonna be much help because I just get a tiny little sickening feeling and as long as I have some food in my stomach, it goes away with in a few minutes. It sounds terrible to have to deal with that. I hope you find something that helps. 💜

Claire_lc profile image
Claire_lc

I really think you should give medical cannabis oil a go. It completely stopped the nausea Jools experienced when she started taking Buprenorphine. Clinics such as Curaleaf and Releaf are staffed by specialist doctors who take your medical history and prescribe accordingly. The oil is great because you can take microdoses using a tiny syringe to measure the amount. You just drop it under your tongue and that's it. At those low doses you won't get high or addicted. Personally I'd rather use that than yet another pharmaceutical product. I hope this helps.

davchar23 profile image
davchar23 in reply to Claire_lc

Claire,

Thank you for your reply and yes it reinforces Joolsg 's statements about cannabis oil which i have never doubted but i am working closely with an understand GP who i want to bring to the party!

Kind regards

Davchar

Typicallygaslit profile image
Typicallygaslit

Not like that, no. Mostly I just feel disgusted when I’m supposed to eat, and it’s difficult to get the food down. I would say this problem has lessened over the year and a half that I’ve been on Buprenorphine, also trying very hard to keep the dose low at max 350 mcg. I do get indigestion pretty badly. I don’t tolerate any anti-nausea medications. I also found that THC cannabis oil made me even more reluctant to eat and I actually lost weight very quickly.

davchar23 profile image
davchar23 in reply to Typicallygaslit

Dear Typicallygasit,

Thank you for your reply. I also don't actually feel disgusted but do not have my normal healthy appetite. My real problem though is that the nausea wakes me. It eases when I take deep breathes or get up. After that and the "sweating" it is just a sickly feeling (not pain) in my gut. As the day goes on the feeling decreases and by evening has almost dissipated

i take 400mcg/ day and that just about blocks my RLS

Very concerned about your comments on cannabis oil. Do you mean it increased the sickly feeling or simply increased the reluctance to eat?

Best regards

Davchar

Typicallygaslit profile image
Typicallygaslit in reply to davchar23

Re cannabis, it made me feel more nauseous over time and I also suffered from even poorer motivation than normal. I really struggled to find it in myself to prepare food and eat it. So a combination of nausea and reluctance and an apathy… hard to explain. I think it also affects my appetite in a different way than the opioid which at least allows me to feel hungry enough to feel the urgency to eat.

davchar23 profile image
davchar23 in reply to Typicallygaslit

Sory forgot to ask but what was your reactions with anti nausea meds. I am on Zoran and i seem to be much weaker and tired?

Davchar

Typicallygaslit profile image
Typicallygaslit in reply to davchar23

I have some kind of disorder which I’m not getting any expert help for as there isn’t any. But I’ve come to the conclusion that I suffer from serotonin toxicity/syndrome and it means I’m unable to tolerate the medications that are black listed for this issue (you can find articles and lists online). It includes ones that antagonise serotonin such as ondansetron. I don’t think I’m alone with this problem but it seems rare. I also think that some of us become more sensitive to meds that mess with serotonin as we get older, so maybe that’s what’s going on with you. Do you feel dizzy? Weak and tired could be signs. Many of the meds on the lists have that effect on me, some of them make me vomit and cause diarrhoea. opioids are also on the list unfortunately which is concomitant with my very troubled relationship with them. I think it may be a problem with the serotonin and dopamine transporters.

Typicallygaslit profile image
Typicallygaslit in reply to davchar23

Are you sure the nausea isn’t silent indigestion and that’s what’s waking you up, because it certainly wakes me up. But it’s noticeable of course when you burp up the acidity in your sleep :(. But it also sometimes just feels unpleasant in the chest area.

Elisse3 profile image
Elisse3 in reply to davchar23

Probably silly to ask but have you tried ginger helps with nausea

davchar23 profile image
davchar23 in reply to Elisse3

Dear Elisse,

it is not a silly statement as i have already tried it but no joy. The trouble is with any such thing such as ginger or probiotics , how long does it take to see any effect and perhaps i didn't try it long enough

Kind regards

Davchar

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