Buprenorphine and nausea

[davchar23]

I have received much support from various persons on this forum concerning the nausea I suffer from the low dose use of buprenorphine to block my RLS. However this symptom remains unresolved and I am posting my situation in case there are some of you who might be able to enlighten me further?

I currently take 2x200mcg buprenorphine tablets each night to successfully block my DA augmented RLS. However the result is a fairly severe nausea which disturbs my sleep and leaves me with discomfort during most of the following day. i have trialled both tablets and patches.

I am about to trial Zofran and a smaller patch (5mcg/hr) but i would be interested to hear from others with this problem

[ChrisColumbus]

I have no personal experience, but Joolsg has advised others with the same problem to use medical cannabis oil with 20% THC and/or Zofran for 10 days. Hopefully the ondansetron (Zofran) will work for you too.

[dancer2]

I am also using buprenorphine for RLS. However, I take it in the form of Belbuca. Belbuca is dispensed as buccal patches that are placed inside the mouth attached to the cheek. I have never had any nausea with this form. However, Belbuca is very expensive (even with insurance). It is ironic that I have been trying to get my insurance to approve buprenorphine tablets because of the cost. I am worried about doing that since I have seen the posts about nausea with the tablets. Also I cannot find anyone who can tell me how to convert the dosage of the buccal patches to the dosage of the tablets.

[707twitcher in reply to dancer2]

The attached cite says to double the buccal dose to switch to sublingual.

pbm.va.gov/PBM/clinicalguid...

One good thing about sublingual - it’s fast acting so start with a dose you think is on the low side and add more in an hour if it doesn’t work.

[Claire_1c]

If you are open to trying medical cannabis oil, as suggested by Jools and Chris above, I can really recommend Releaf. I've used them recently and they were wonderful. So kind and helpful. I tried Lyphe a few years ago and didn't find them to be very professional. Releaf seem to know all about oil, whereas Lyphe wanted me to vape dried herbs. They will prequalify you, but it's very straightforward and you will definitely be seen. It's easy to take very tiny quantities using a millilitre syringe. You wouldn't need anywhere enough to make you high.