A story with no ending.
If you don't like stories skip to "THE END"
I have an ex-colleague who used to teach physiology using guided imagery. I attended one of her lectures once on the oxygenation of blood. All the students had to close their eyes and sit, (or lie down) comfortably.
Then she began.
I had to imagine I was a haemoglobin molecule sitting in a boat (red blood cell) and was guided through various adventures which depicted the oxygenation and deoxygenaton of blood.
I'm one of those strange people who enjoy guided imagery and get really caught up in it. My best experience of it was at a conference about health and spirituality in Durham Cathedral.
I usually have to be dragged out of the experience to cold reality. Sometimes to the sound of snoring. Never my own.
To get back to the point, I tnought I'd write a guided imagery script for how iron can help with RLS. However as I went along it turned into a story. I'd like to share the story.
I also have an ulterior motive. I don't know the ending so I'm going to be asking you.
Once upon a time Fred the ferrous molecule was resting in his universe. A huge place populated by millions of ferrous molecules in a place called "Capsules : take one each day",
Like all ferrous molecules, Fred was with his close partner and friend, Betty bisglycinate. So attached were they, that they never let go of each other.
Fred was at peace, but was sometimes disturbed by thoughts about what his purpose was.
Then one day, apocolypse. Freds whole world was taken and put in a hot, wet dark place followed by a deluge of an orange liquid. Fred's world was washed down a long tunnel and came to rest in a lake of acid.
His world was torn apart and he found Betty being torn away from him.
He was horrified, he felt he had no control over what was happening to him. He was afraid, because he coudn't predict what was going to happen next.
Fred and all the other ferrous molecules were swept into another tunnel whose walls were ridged and bent into many folds. On all the folds were what looked like stalactites. Fred managed to cling onto one of these alongside some of his friends.
He noticed that many ferrous molecules didn't make it and were swept away.
He then felt himself grabbed by another molecule wearing a tee shirt labelled "ferroportin". Just before he was dragged into the stalactite he saw similar molecules attempting the same, but they were attacked by yet other molecules with "hepcidin" tee shirts and many of his ferrous friends were left behind.
One of the few ferrous molecules left, Fred now found himself in a narrow tunnel filled with a clear fluid. There was a strong current and there were lots of different molecules and cells carried along in it. There were a lot of cells shaped like doughnuts (donuts).
Then along came a bus! "Hello" said the bus, "I'm Thomas, the transferrin molecule.. "Get in I'll take where you need to go",
Fred got on. He was relieved that he was being looked after and somebody, at last, seemed to know what he was supposed to do.
He noticed the bus was less than 40% full, but all his ferrous friends had been picked up by either Thomas or the other buses he could see.
Some time passed as Thomas was swept through a labyrinth of tunnels and a large cavern that echoed with loud rhythmic sounds. Some buses went one way and others another.
Thomas came to a transparent wall and Thomas said, "Time to get out, nearly there".
Fred got out. On the wall was a sign, "Blood Brain Barrier. Limited entry". Before Fred could think he was grabbed and taken through the wall, but many of his friends were again left behind.
He now found himself in another liquid which contained other molecules, but no cells.
He was approached. "Hello, I'm Fuyoku ferritin and I'm going to be looking after you until you're needed".
Fred was happy again that he was being looked after and was needed, nearing his final goal.
Well it isn't really, I don't know what happens next.
I know that according to some theories lack of iron is the main cause of RLS.
(Purely as this story is about Fred, I won't be mentioning other theories, although I'm fond of the marmite one).
I also know that according to some theories dopamine deficiency and/or downreglation of dopamine receptors, glutmate excess and/or an underlying adenosine dysfunction lead to RLS symptoms.
I haven't a clue what the connection between the two is.
Your homework for tonight is, should you choose to accept it, look up what's the connection between iron, dopamine, glutamate and adenosine. You can use Google Scholar, it's allowed.
Tell me what you find out and the best answer gets a chocolate muffin,