This is the main conclusion from a recent meta study on medicinal cannabis.
This has been a recurring question on this forum.
"Despite the conventional wisdom, both in the popular press and much of the scientific community that only CBD has medical benefits while THC merely makes one high, our results suggest that THC may be more important than CBD in generating therapeutic benefits. In our study, CBD appears to have little effect at all, while THC generates measurable improvements in symptom relief."
I'll post the link in following post.
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Madlegs1
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I have tried numerous strains of cannabis including one that had been bred to a high CBD strain and I've always had better relief from the higher THC ones.
I tried CBD oil on its own with no observable effect either. I look forward to the post.
I've spent a fortune buying CBD oil pills from CBD brothers over the past 2 years. Stupid of me because they made no difference as they do not contain any THC.
Recently, I've been using a CBD oil vape containing THC made by a chemistry graduate friend of my daughter ( Illegal here in UK but I no longer care that I have to break the law!) and it has knocked me out and I've been in such a deep sleep the RLS has not woken me up. Sadly, I won't be able to buy any more as it's too expensive -but it clearly works.
Here is an interesting article detailing the endocannabinoid system. The name CBD has many connotations. For the therapeutic benefit, you need "full spectrum" CBD oil (not just the isolated CBD component). None of this involves the THC component. That said, the full spectrum oil enhances wakefulness. You might say - well I DON'T need that! But enhancing wakefulness - during the day - leaves the door open to also enhance the sleep/wake cycle and have a more normal sleep cycle. articles.mercola.com/sites/...
ZZZZZZZZZZZZZZ - Think what you want about Mercola - scroll down on that link to the Comments - a wealth of information. I take EVERYONE with a grain of salt but don't disparage the independent information he might provide
It is one of the few articles that he is NOT selling his own product. I don't think he has a CBD product in his line-up. It's a little deep in the comments before you can find a suggested product to try. I never even knew there was an endocannabinoid system. Caveat Emptor (buyer beware) with Mercola's or anyone's products. I should take a picture of all the supplements I tried - mostly for RLS and Insomnia.
I don't think the supplements I have tried for rls (with an almost 100% failure rate) would fit in a single picture. I would be photographing for a day to capture them all.
I have been prescribed cannabis 1 part THC and 2 parts CBD. I believe the THC is necessary to help sleep and reduce RLS. I have been given a script for 1 part THC and 1 part CBD as it means I can reduce the dosage and it will be cheaper for me. I live in Australia where if you get the right doctor they can write you a script but it is expensive - $800 for 3 months supply but I manage to not use it constantly so can stretch it out.
Hah, yet again what at first appears to be a simple solution just gets more and more complicated the more you look at it. I was considering trying CBD, but now completely put off. The thought of either the expense and not getting any benefit, getting the right ratio of THC, cognisance of the law, availability is enough to make you turn to drugs!
I have some fond memories of my student days in a haze of smoke. Not so fond about the paranoia and failing all my exams. Overall don't really want to go back there again.
I wonder what effect LSD would have on RLS and insomnia?
I've tried various pills, ointments, tea, gummies, and vapes with thc and cbd for my RLS, back pain and insomnia. I've found that only vaping has helped. I agree that cbd doesn't seem to do anything. (I've tried straight cbd alone and it didn't do anything). Still looking for the perfect concentration.
I watched a youtube video recently of one of the top Israeli cannabis researchers (medical research). He cited a really interesting example of kids with profound autism and violent tendencies. A certain strain of cannabis had an incredibly positive effect on their behaviour and cognitive ability. At one stage they ran out of the strain and substituted a different but genetically similar strain and the behaviour of the kids immediately disimproved - pretty much to the pre-cannabis levels. It seems to be incredibly strain specific. The moral I take is that if you find a strain that works for rls it is worth sticking with it. I wish I could find that strain ...
The guy also told a funny anecdote about a fellow researcher who had in desperation prescribed cannabis for an elderly patient suffering from chronic pain that had failed to respond to any other treatments. He phoned her a few days after she started the cannabis asking if it was having a positive impact. 'Oh doctor', she said ' the cannabis has changed my life.' He was delighted. 'The pain is improved?' he asked. 'Oh no doctor, the pain is the same as ever. But since I started cannabis my grandson visits me every evening.'
Hey, I recently read that Cannabis use is on the increase, but mainly in older folks! It seems that now us old hippies have retired and left behind the responsibilities of work and raising families and with increasing acceptability of cannabis use, we're returning to past ways.
All sorts of benefits are now being claimed, for MS, for epilepsy, for chronic pain and RLS.
Sadly, the kind of cannabis that's around these days is apparently much stronger than in my youth. Additionally, us older folks are physiologically less able to deal with the effects. So that's not a habit I'll be revisiting.
In the meantime, it seems there's a way to go in working out the best formulation of cannabinoids for particular conditions. Then demonstrating how effective it is. So I don't think I'll be rushing to Holland & Barrets just yet.
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