My wife was suffering for over 4 years with PSP. During the treatment, brain scan MRI showed that her brain was slightly shrunk. Many of the other patients too had brain disfigurement. It is on this that I would like to comment.
As all know, 60 -65% of the brain is cholesterol. According to the Ayurvedic doctors, the brain has to be continuously fed to keep it well and functional. So cholesterol is a major food for the brain. Allopathy feels that cholesterol levels of 230 and above is the root cause of artery blockage, resulting in stroke and CVD. Instead of lowering the cholesterol level, if we could get the excess cholesterol to the brain, then the body's cholesterol level will come down, and the brain retains its lost cholesterol. Ayurveda has found that coconut oil is the best medium to break the blood brain barrier, and carry nutrition for the brain to the brain. Allopathic doctors may want to look into this aspect seriously and check the veracity.
I will always be available for any further ideas on this, if required.