Advice on new treatments .

[jackrussell]

My husband has prostate cancer and has been on hormone treatment for 12years , he is in good health considering his age 89years . However his PSA readings are showing there is more movement than usual in March this year it was 5.1 in May it was 8.7 and today it is 10.8 .

Today he had his annual ( since Covid made appointments via the phone ) with his local hospital prostate clinic , and I suggested as the reading was moving more quickly, that perhaps we should look at a reappraisal of the situation , ( his G P appears to be doing nothing at all . ) and he said he would arrange an appointment with Urology ,

My question is does any one know of the up to date treatment that is available ,at the moment he is on Zoladex injections 3 monthly , and Bicalutamide 50 mcg daily ( these replaced his origanal tablets ) .

Any advice would be very much appreciated , as I am sure there are many others in the same position. Thank you .

[Tall_Allen]

He should be able to get abiraterone or enzalutamide. Probably Zometa too, if he has osteoporosis.

[jackrussell in reply to Tall_Allen]

Thank you, it’s always very helpful to have knowledge of what may be offered or could be offered , better than no knowledge at all. He has been having some problems ( like most of us ) with arthritis .he paid for an MRI on his hip as he was concerned ,turned out to be signs of arthritis, he also has it in shoulders and hands ,,but thank you once again .

[Currumpaw in reply to jackrussell]

It seems that medication has been the only treatment your husband has had.

I would suggest a mp 3.0T MRI with the possibility of an in-bore biopsy if needed.

Should a biopsy be necessary a trans perineal biopsy greatly reduces the chance of infection and allows access to areas of the prostate that the trans rectal doesn't.

When one is going to war, the best reconnaissance can mean victory. Once you know his situation then the best treatment choices can be discussed.

As his health is otherwise good, choosing the best treatment can mean 10 years or more of an enjoyable time towards the end of life or not so much.

My best to you.

Currumpaw

[Magnus1964]

He shou switch to zytiga. If the side effects are too much for him, then try xtandi.

[jackrussell in reply to Magnus1964]

Thank you for your reply ,noted.

[Grumpyswife]

I think my husband was able to increase the bicalutamide which helped for a short time. You could ask.

[jackrussell in reply to Grumpyswife]

Thank you for your reply

[dac500]

In my opinion, he should be seeing a medical oncologist, rather than a urologist.

[jackrussell in reply to dac500]

Thank you for your reply. I will be aware of that when we get an appointment with whoever it is that an appointment is being made with., and I will definitely query that , I do feel it is advantages to be aware of these things . Do you have a definite reason for suggesting this , ( I do wonder if the “ nurse “ my husband spoke to will get the appointment with an oncologist ) as apposed to the Urologist .

[dac500 in reply to jackrussell]

I made the mistake of relying solely on a urologist during my initial treatment and subsequent recurrence. Now, I am fighting metastatic prostate cancer.

[Cateydid in reply to dac500]

I absolutely agree with seeing an oncologist who specializes in prostate cancer!!!

[Gabby643]

See an Oncologist( MO)

[jackrussell in reply to Gabby643]

Thank you for your reply