I had my consultation with my oncologist on the 30th of Oct, results of my blood test were that my PSA was 0.01, but my Testosterone was so low that it didn't even register. This is 8 months after my last ADT Implant, and 5 months after the drug has been depleted by my body.
This really surprised me, I expected my Testosterone to be at least on the road to recovery, suppose it explains why I feel so crap
Is this normal after ADT, I was only on ADT for 7 months? Is it worth investigating taking something to increase my Testosterone?
Regards,
Will
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Will60
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Never heard of Colmid or HCG TBH, in fact never come across the ability to jump start the production of Testosterone. Are you aware of anyone who has undergone this process?
Yes. Me, in fact. And several bodybuilders from whom I learned it. Their natural T is suppressed by taking T, so they start the off-cycle with two sub-Q HCG injections and a few weeks of clomid.
Hmmm that is an interesting alternative, wonder why that treatment is not suggested for PCa patients with Low T after treatment. Its not like they are introducing any additional risk, because you are just encouraging T to increase naturally.
i tried Clomid and it did nothing. so don't get your hopes up. testosterone supplement is a possibility but MOs obviously don't like it. You have to take some risks.
According to my understanding, what you're experiencing is most definitely not normal; about 90% of men have their T fully recovered by now. If the jumpstart doesn't work, you'll need T replacement. Good luck.
I took one 3 month injection of Zoladex and it took 6 months to get T back to 0.79. It was .0.09 for 3 months. I have a history of Low T. My baseline is 3 from 10 years ago. I have potency and PSA is less than 0.01 Everyone is different. Can you support you assertion with evidence?
Hi Steve, at my latest consultation, End of May 2021, my PSA was 0.03 and T was 7.4 nmol/L (2.13 ng/dL), still below normal T but, slowly, making a come back. Just amazed that it takes so long😩
Everyone’s different - be patient. I’m on IADT (intermittent ADT) and had periods up to 7 months before ANY T recovery after Firmagon/Lupron/Zytiga was out of system. Then takes 6-12 months for full recovery. MedOnc warned my highest T may decrease from baseline each cycle, which also seems to be occurring.
My T is still very low and I stopped a 2yr hormone treatment 1.5 years ago. I have thought about T replacement but doc is not eager andI'm fine waiting.
Have you read what Tall_Allen said above, "Clomid or hCG can sometimes jump start the sleeping cells that are supposed to make T"? Did they give any reason why your T is still low after so long?
It took me about a year after my last 3mo Eligard deposit, so about 9mo post ADT (in theory) to see any “T” lever above castration @ 100 (Eligard states that to be 50NG/DL in their literature). Then after that, it slowly crept up over the months to lever off @ 400 recently. That being low in the scale of acceptable levels but I have no base line so again... time will tell! Many Dr’s have been prodding me towards “T” replacement therapy in an attempt to help with my daunting cognitive / executive side effects. Those are the last two (but lingering) of my many, many ADT side effects which were mostly gone as my “T” hit 100 +/- mark! My thought (for myself anyway) is don’t kick a sleeping dog and give your body time to recover from being castrated and with out any additional drugs!!
Mine came back a bit sooner. However, I would NOT be in a rush to get testosterone back, even though you don't feel so great. Remember, testosterone is to prostate cancer as gasoline is to fire. The testosterone will likely eventually return. Just keep hoping and praying that the PSA doesn't come back with it.
Yeah understand what your saying in retrospect, if I knew how ADT would affect me I wouldn't have agreed to that part of the treatment. And if my PSA did start rising I would just let nature take its course rather than endure the torture of ADT.
So sorry your ADT was so bad, but letting nature takes its course could be metastic prostate cancer, with bone pain, fluid on your abdomen (ascites)(which I saw a dear friend endure), and death (same friend a few months later). So, keep plugging. It should get better.
Yeah know what saying, but didnt respond well at all with ADT. Really had a profound affect on my mental well being. Suppose I will never say never. Hopefully I may not get the opportunity to have to make that decision.
Surprised the heck out of me that at age 74 after 6 mo lupron it took two months to go from <12 ng/ml to 350 ng/ml, but everyone is different. Dunno where that is compared to MY "normal".
There's a video around here somewhere where a doctor says new studies show its take a lot longer for T to return than previously thought and a substantial number of patients it never returns at all. I was told by one of the testosterone guys around here that prescribes it that he has a lot of clients that have had prostate cancer. yes, it will feed metastasized cancer, but you will probably know that pretty quickly and then you just quit seems like. It all depends on whether you want to take the risk. No one really knows if they have been cured or not, at least not for a long time. The subject has not been well studied. A lot of it is a quality of life issue.
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