Steroid induced T2 diabetes: Sorry this is a long... - PMRGCAuk

PMRGCAuk

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Steroid induced T2 diabetes

Mandyq profile image
Mandyq
•10 Replies

Sorry this is a long story !

Started on Pred (15mg) nearly 3 years ago. Gradually reduced and now at 6mg. Planning to Reduce 1/2 mg every 6-8 weeks 🤞🤞

18 months ago prescribed metformin for T2 diabetes - probably associated with steroids. HBa1c was still too high so metformin dosage increased and Dapagliflozin added in July 2024.

Since then I’ve felt increasingly unwell ( tired, light headed, occasional palpitations etc) and to add to my woes in September 2024 was diagnosed with anaemia and ferrous sulphate was added to my various potions.

I now look back to the days when I felt “OK” my only medication then was low dosage tablet for high BP and prednisolone for PMR.

I’m now wondering if the reason I feel so rough is because all my additional medications are “fighting “ each other. I’m inclined to suggest to GP that I start to reduce the diabetes meds as I really feel that my general malaise started soon after these were thrown into the mix.

Has anyone had steroid induced diabetes that required medication - did the need for medication fall as Pred was reduced

As ever thanks to everyone on this site, GP is good but I feel personal experience is often more useful

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Mandyq
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SnazzyD profile image
SnazzyD

Are you checking your blood sugar and blood pressure when you feel unwell? Did you have to start medication in spite of radically reducing carbohydrates back when? Steroids make your liver breakdown reserves to make glucose which one can’t influence. If one then eats carbohydrates it adds to the blood glucose and you can end up coasting on a consistently high blood sugar. This bit you can influence. Some here have reversed their T2D diagnosis and others, like me, kept their HbA1c at a good level.

Was the Metformin supplemented with the new drug because it wasn’t working?

The side effect list includes feeling dizzy and low blood sugar and blood pressure. I think you need to speak to your doctor as you feel so unwell.

Mandyq profile image
Mandyq• in reply toSnazzyD

Thanks Snazzy - it wasn’t ever suggested that I check my blood sugar but I do check my BP regularly anyway and it’s always OK.

I wouldn’t say I radically reduced carbs tho I did cut down on the obvious and easy!

I’m due a blood test next week to check if anaemia is responding and also HBa1c and I’ll organise a F2F with GP then. I find them quite approachable and understanding so I’m hoping I can agree a way forward.

PMRpro profile image
PMRproAmbassador

I was going to ask exactly the same as SnazzyD - steroid induced diabetes isn't the same as Type 2 diabetes and for a lot of us, radically cutting carbs, above all processed carbs and carbs like potatoes, rice, pasta etc, and limiting fruit, can keep Hba1c in the pre-diabetes zone and avoids adding medications. Some people find that adjusting their eating patterns relative to pred dose timing also makes a massive difference.

What WERE your Hba1c numbers?

And the lightheadedness and palpitations - is the lightheadedness constant or is it now and again? Does it relate to the palpitations?

Mandyq profile image
Mandyq• in reply toPMRpro

Thanks for the reply -

re HBa1c, for years I hovered in the pre diabetes zone (between 40-44) and was told to watch what I ate, that was all before PMR struck!

For the first year or so of taking Pred I remained at that level (testing only done every 12 months as part of annual MOT) then went up to 48 and I was put on metformin (1000per day) despite that just under a year ago it went up to 55 and metformin was increased and then Dapagliflozin thrown into the mix.

As a result of this and some reduction in carbs I’ve lost weight and last test in October indicated HBa1c was down to 48.

Next test due next week and if HBa1c has continued to fall I’ll be suggesting I reduce metformin etc.

Why are health issues so complex, I remember being young footloose and fancy free and taking the odd vitamin supplement seemed to be all that was needed to keep living life to the full 🤣🤣

PMRpro profile image
PMRproAmbassador• in reply toMandyq

Ah yes - but with age comes not only wisdom (maybe) but also wear and tear!!

Relying on medication is a false friend really - better to try to tackle the evil at source, however hard it may feel, so the medication is there if the basic approach fails.

Excelsior80 profile image
Excelsior80• in reply toPMRpro

I have steroid induced prediabetes and my GP seemed pretty unconcerned, she said its the steroids it'll go when you are off them ... I am cutting carbs, at least the easy ones .... is she right not to worry? currently at 5 1/2mg pred.

PMRpro profile image
PMRproAmbassador• in reply toExcelsior80

If it is ony pre-diabetes it is probably acceptable but high BS is high BS whatever is underlying it and the high sugar levels cause damage to cells. She should be encouraging you to try harder with diet if there is room to play there. Timing of eating carbs relative to taking pred can also make a difference - there has been a lot of discussion about that in the last 6 months or so.

SnazzyD profile image
SnazzyD• in reply toExcelsior80

Goodness. I always say don’t wait for the revolution. What if you have flares and don’t reduce at a steady lick or that your PMR doesn’t allow a smart descent? Or that your adrenal function doesn’t return at the pace you want it to? You run the risk of getting insulin resistance if your pancreas is having to keep putting out in response to the spike in glucose. It depends how sensitive to Pred’s glucose raising powers you are. Personally, I found I had to keep to a fairly strict low carb diet even after getting to zero for some time; my metabolism didn’t snap back to normal. As PMRPro says, a raised blood sugar is a raised sugar. Your body doesn’t care about intention or label given to it, the effect is the same.

Mandyq profile image
Mandyq• in reply toSnazzyD

Thanks snazzyD - I think I’ll invest in a BSM, it would be useful to know how my blood sugars react to what I eat and when and particularly the impact of the various medications.

Mgt1234 profile image
Mgt1234

Hi Mandyq, like you I have type 2 steroid induced diabetes 500mg slow release. I was told when diagnosed I didn’t need to monitor it but I like to have my finger on the pulse so to speak and do monitor it, initially once a day and now just as when I feel it necessary. I take 2 metformin a day and my last HBA1C measured at 44. I do try to keep my carbs low but am not always successful. I wish you much success. Love Margaret

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