Just wondered……..

[Griggser]

So I’m on 450mg if Pregablin and 40mg of Amitripyline along with an anti viral. What I was wondering is do these drugs also help with PMR? I only ask as I’ve been trying to reduce my steroids and have never got below 12mg. Well my this week I dropped from 11mg, yes you read that right, to 10mg and I’ve not noticed any increase in pain levels, I just hope this continues but wonder what will happen when I stop taking the Pregablin and Amitripyline! I take these for Post Herpetic Neuralgia and they have eased the symptoms but not fully relieved them.

[PMRpro Ambassador]

There is no real reason why they should - unless some of the PMR pain is due to poor blood flow to nerves. But if it is improving the post-herpetic neuralgia it may be that the stress of that has been "feeding" the PMR - I have seen a few people who had their hip replacement done and subsequently managed to steadily reduce their pred dose.

[MrsNails]

Hi Griggser - You just never know 😉 if it helps after all you’ve been that’s great. Long may it continue to help 🙏🏼Hope you are improving?

MrsN

[Jackoh]

Hi Griggster. I have no proof but I think being on Amitriptyline has helped me on my very slow descent. In the evening, I take the Amitriptyline about 7 pm. It has helped me relax and my PMR symptoms which often just rear their head a little at about 5/6pm seem to disappear. 💐

[USAGCA]

I doubt that the pregabalin or amitriptyline are helping with the PMR. Some people believe that shingles may be related to PMR/GCA. I take pregabalin (much smaller dose than you) and the antiviral. I don’t plan on stopping the antiviral until I am off immunosuppressive meds, or until I have no more shingles symptoms.

[softekcom]

In the five years before my diagnosis with PMR I used Pregabalin, Amitriptyline, Tramadol and a patch - forget the name. While they helped with sleep and sometimes some types of pain, they did not help with the PMR pain. The Rheumy i saw in July (who wanted me to come off Pred completely so I could be tested for inflammation markers) said the Pred was probably covering up the other pain as well as the PMR pain. To each his own.

[Magster54]

Interesting Griggser, I'm on the same dose of Pregabalin and 60mg Amitriptyline for PHN. Have been wondering the sane thing as you