Alendronic acid query: Hi, I was diagnosed with GCA... - PMRGCAuk

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Alendronic acid query

Lyndaki profile image
18 Replies

Hi,

I was diagnosed with GCA & PMR in November 2018. I was put on 60mg prednisolone along with AA, lanzoprazole,& Adcal . I am now down to 2.5mg prednisolone & doing ok apart from tiredness occasionally . I recently went for a dental check up & need a tooth stump removing which might entail cutting the gum. The dentist made the comment that as I’m on AA, the healing process may take longer. My question is a) can I just stop taking AA, & b) if I do, how long before it is out of my system? (When I said I’d stop taking it before the extraction, the dentist said it would still be in my system)

Thanks all in advance.

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Lyndaki profile image
Lyndaki
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18 Replies
DorsetLady profile image
DorsetLadyPMRGCAuk volunteer

See this FAQ post - healthunlocked.com/pmrgcauk...

Yes you can stop it, and there seems to be some dispute on how long it stays in body...the benefits should last 2-3 years, how long the negative effects last, not sure.

Lyndaki profile image
Lyndaki in reply toDorsetLady

Thanks

PMRpro profile image
PMRproAmbassador

AA is unlikely to ever be out of your system - it is firmly bound in the bones. The last figures to be quoted said 15 years, up from 10 years previously. They are maybe slightly shorter than the time since it was first widely used. That is why they say to get any potentially invasive dental work done before starting taking it.

Lyndaki profile image
Lyndaki in reply toPMRpro

Hmmm thanks for the info!

Janstr profile image
Janstr

I was in the same boat as you Lyndaki, & by dentist aren’t me to a specialist because of the AA

Lyndaki profile image
Lyndaki in reply toJanstr

Yes, I’ve been referred too!

AmberAliona profile image
AmberAliona

Hi there, I was prescribed Alendronic Acid by my then GP despite having severe reflux. I lasted 5 days before the pain from the reflux became too much. I stopped it at that point. My new GP says I should never have even tried it. Good luck to you, I believe it does work for many. Take care.

Lyndaki profile image
Lyndaki in reply toAmberAliona

Thanks. I have no problem with it, just querying how long it stays in system....sounds like a long time!

ritter profile image
ritter

Well I am sorry but I do not know how long it stays.what I do know that AA does not work as well after 3 years it clogs arterys and just a build of calcium .

PMRpro profile image
PMRproAmbassador in reply toritter

Have you got a reference to back that up? I'd be interested to see it.

In fact, this

ncbi.nlm.nih.gov/pmc/articl...

concluded

"Bisphosphonates seem to have an inhibitory effect on the atherosclerotic process; however, larger placebo-controlled studies are needed to better clarify this issue."

ritter profile image
ritter in reply toritter

I havnt sorry I Googled a web site to get that info..

PMRpro profile image
PMRproAmbassador in reply toritter

Sounds like a dodgy site to me ...

ritter profile image
ritter in reply toPMRpro

Right I shall not repeat that again do sorry

HeronNS profile image
HeronNS in reply toritter

It's true you shouldn't take it much longer than that but for a different reason. AA inhibits the "remodelling" of bone. In other words, old bone is no longer removed, so new bone is deposited on what is an increasingly aging matrix. This is what can lead to atypical fractures and why people should only take the med for a couple or three years, to get the most benefit and avoid the shortcomings - which can be dire.

Lyndaki profile image
Lyndaki in reply toHeronNS

Thank you! I’m learning new stuff every day on this site!

JudithWarrior profile image
JudithWarrior

Yes I believe HeronNS is correct - many doctors are now advising no more than 3 - 4 years. I won't take it because of how it's affected my mum with severe damage to oesophagus and horrid symptoms - apparently it affects up to 25% of people in this respect. I'm trying alternative ways to keep my bones strong and will test these out on the next Dexa scan. If I can avoid taking it - I will. Have read a lot about it in book " My Bones." My rheumy said the info wasn't probably trustworthy - but I'm not convinced and he hasn't read the book!!!!

bakingD profile image
bakingD in reply toJudithWarrior

I feel the same the book made a lot of sense- have asked for 1 year to improve my bone density on my own!weighted vest , a bit of skipping, high calcium diet, vit d and k2 !!

Lyndaki profile image
Lyndaki in reply toJudithWarrior

Thankfully I’ve never had any side effects & been on it 2 years & 9 months so….🤞

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