Prednisolone & Mycophenolate withdrawal symptoms - severe night sweats and hot flushes. Is this withdrawal symptoms?

[lindyloo25]

Please can anyone advice me if they got terrible night sweats, and hot flushes through the day, when withdrawing from Prednisolone, and how long it will take to improve. I have been reducing by 1mg a month. Now on 8&1/2mg. Please help.

[jinasc]

Now this is left field - have you had the menopause?

[piglette]

I got the most awful hot flushes even when not reducing. One of the worst side effects of pred I felt. It has got better now I am at 5mg.

[SheffieldJane]

This symptom has almost gone for me now I am down to 7 mgs. I just get a flush of warmth sometimes. I wonder if Mycophenolate is making this symptom more severe? Is it in the side effects listed?

It does seem reminiscent of the Menopause. All sorts of female wisdom on line to make those symptoms bearable. Watch your sugar intake.

[PMRpro Ambassador]

A return of night sweats and flushes has always been a sure sign for me that I have reduced to too low a dose of pred and am letting in a flare.

[Pinkpepper in reply to PMRpro]

Very interested to read about your night sweats and hot flushes when reducing too low. Sounds just like my situation. What dosage were you taking at the time and how much did you increase please?

[PMRpro Ambassador in reply to Pinkpepper]

I have flared at various levels! It depends on whether it is a proper disease activity flare or because of reducing a tad too far. When it is reducing that did it I return to the previous dose. If it is a disease activity flare I go up 5mg to see if that is enough and then reduce to the new right dose.

[Pinkpepper in reply to PMRpro]

Thank you.

[Pinkpepper in reply to PMRpro]

Hi, I had a really chesty cough and cold for about a month while still reducing my dosage to 3mg. Wonder if this could be the reason I’m getting hot flushes presently as maybe I should have been increasing my dose. Was feeling the heat indoors for about a month before I dropped to 2.5mg, next day the flushes started! Can you throw any light as to whether you have had similar symptoms, you seem to know mor3 about PMR than my doctor!

[PMRpro Ambassador in reply to Pinkpepper]

I have PMR - you doctor doesn't!!!!!

You really shouldn't have continued reducing when unwell. I'd say you had arrived at your "right dose" when you got to 3mg - the lowest dose that manages the inflammation. If I go too low - the sweats return.

[Pinkpepper in reply to PMRpro]

I don’t get any help from my doctor really, don’t think they know much about PMR, that’s why I find this forum so helpful. I’ve increased to 5mg for the last three days but flushes are continuing, don’t whether to increase further.

[PMRpro Ambassador in reply to Pinkpepper]

Just be patient and see how you get on.

[Pinkpepper in reply to PMRpro]

Thanks for your advice, you’re very kind.

[bunnymom]

I intermittently have hot flashes. They come and go. I'm at 7. Not sure why. I found that a natural sleep aid (can't remember name) gave terrific hot flashes at night. Better now. I have found that benedryl helps me sleep thru the night.