we all know I move back to the north east to go to a real pro rheumatologist. He proceeded to reduce me so quickly I had a third relapse at 12mg. It made me sicker than I have ever been in my entire life. My CRP went to 33 and my ESR went to 42. I upped my dose to 20 mg from 10 and my CRP went down to 10.4 and my ESR went down to 31. Have had other blood test and numbers went down today my CRP went up to 9.9 and my ESR back up to 40. I have a new rheumatologist who gave me my first shot of Actemra and we did not increase the prednisone. This is crazy for my numbers to move around so quickly and this is all in one month. I do not know of any infections I did however tear my meniscus in 2 places and am in constant pain. This was three months ago and also have steroid myopathy. I am trying to keep this short because my other issues are huge. After two years and three months of GCA and high prednisone and for the three years prior PMR, I am trying not to lose faith. I am hoping the Actemra will not bring on numerous infections and all the other things you can acquire before I can get down to 10. Any thoughts?