I saw my consultant a few days ago and he reported that my latest blood tests from December 2012 show that my AMA is now negative but previously it has been positive. It was initially discovered that I had a AMA antibody back in 2007 which was positive after some routine blood tests. A couple of years ago my AMA reverted back to negative and then positive once more. My LFT's have always been normal but my consultant suspected PBC because of the positive AMA. It just seems odd that the AMA can fluctuate from positive to negative and back again, has anyone else had a similar experience?
All the best.