I have chronic severe daily nausea with many other chronic issues such as burning urination. I am in so much pain on a regular basis that I am unable to participate in normal life activities. My Aunt was recently diagnosed with PBC which got me wondering about myself. I am only 24 and have had an elevated ALP level ranging from 150 to 163 (top reference rang of 115) on 4 separate tests over the last year and a half. The other LFT numbers have been normal. I also had a severe case of pruritus a few years ago that came on suddenly for no apparent reason, but thankfully went away after a few months. I asked my GP to do the AMA test and an igm test after researching PBC for my Aunt. My AMA level was 24.3 which fell into the equivocal range. Negative less than 20 and positive greater than 24.9. I have read that in PBC, the Igm level is almost always elevated and my level was actually in the very bottom of the normal range. I would appreciate any comments about my situation. Has anyone first had an AMA level in the equivocal range and still ended up being diagnosed with PBC. Can you have PBC without an elevetated Igm level? Am I too young to have PBC?