Risedronate Sodium and teeth problems

[Oludeniz2017]

I have recently been prescribed with Risedronate Sodium after a Dexa bone scan. I went to the dentist last week and I need an extraction. They explained to me that this drug can cause problems with the healing. I won't go into detail but sounds potentially horrific. Because of PBC my teeth/gums are already not in a great place and I'm worried about any future extractions. Does anyone have any experience of this please?

[Oidra]

I have taken Risedronate for over 5 years after a knee fracture and a previous back bone fracture. My recent dexa bone scan shows that my bones are very good for my age (82) apart from a weakness in my back and my doctor advised because of my age I should continue with it. My gum disease started many years before I knew I had PBC and I had treatment at the London Dental hospital for many years so I have managed to keep a lot of teeth and also have 2 dental implants where they couldn`t be saved. My dentist knows I take Risedronate but has never mentioned the problems you talk about.On the other hand I have not needed any extractions since I started taking it.

Many of us with PBC have teeth and gum problems that have to be sorted. Having a full brace on my leg for 10 weeks after a fall was also a problem. So you need to protect both but as it is causing you concern and I would ask the PBC Foundation if there is information out there that can advise you and put your mind at rest.

Olwen

[Oludeniz2017 in reply to Oidra]

Thank you Oidra

[Oludeniz2017 in reply to Oidra]

Oidra would they see this post and reply or is there a better way to contact them please?

[gillrich in reply to Oidra]

Absolutely agree pbc foundation always the place to find accurate upto date info

[Oidra]

ww.pbcfoundation.org.uk

This the site for anyone with PBC to get the correct information. Look them up, they have lots of talks on line and you can speak to someone if you are worried.

Olwen

[Readlots]

Hi, my Mum with PBC had the same situation. She was on alendronic acid for osteoporosis, known to be linked with PBC, and found during a routine dexa scan. She started to have problems with her teeth. She needed an extraction. She was referred to the local hospital because of the additional risks of bleeding due to low platelets. The hospital initially refused to treat her as she was on alendronic acid which increases the risk of necrosis. After much backwards and forwards between her dentist ( who was fantastic) and the hospital they removed the tooth and she was fine. She did have to do a lot of mouth rinsing with saline to make sure she didn’t get an infection. If you need the work, keep pushing, you will find someone with the knowledge to do it, it’s just frustrating. I know they are meant to tell people to get dental work done before they start taking these drugs but they don’t. Also you may not need treatment until you’ve been on it for a while and even if you stop taking it, the risk of necrosis remains. You have my sympathy. Just to reiterate, Mum did have an extraction. She did not get necrosis. You just need to find a good dentist who knows what the are doing.

[iagra]

I had osteopenia well before PBC that later became osteoporosis in some areas, but not all. I have three tooth implants that healed fine, regardless of of some bone loss and receding gums that I also had years and years before PBC. Some bone loss maybe possible with PBC, if you do a fractional ALP (isoenzymes) test, it'll tell you what is causing high ALP, bone, liver, intestines, placenta and one other, can't remember what.

[Oludeniz2017 in reply to iagra]

Are you in the UK? Never heard of this test.

[iagra]

I'm in the US. It's called: Alkaline Phosphatase Isoenzymes test (Fractional ALP). It'll give a total number for ALP, but, in addition, will show which of the specific enzymes are contributing to high ALP: Intestinal Isoenzymes, Bone Isoenzymes, Liver Isoenzymes, Placental Isoenzymes, Macrohepatic Isoenzymes. It provides more information than a simple ALP test. In terms of the test itself, it is the same simple blood draw from the vein, just like for the ALP test. No prep is required.