10 day difference in labs before and after ... - PBC Foundation

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10 day difference in labs before and after pain medication

shadowme2 profile image
27 Replies

I went by ambulance to the ER for severe muscle spasms on left side of my back. They drew blood before giving me any medication. While waiting for results I was given an i.v. of morphine and some sort of muscle relaxer. All labs came back in normal range so I was released with instructions to take Naproxen 500mg and Methocarbamol 750mg until script ran out. I only took Naproxen for 3 days (too fatigued already thank you) and the other one for 7 days. I went to my Primary for follow up urine sample, so asked her to run another hepatic panel. 5/14 hospital labs were Ast 24, Alt 27, Alk phos 147. Super! Labs 10 days later on 5/22 after pain meds Ast 48, Alt 61, Alk Phos 193. Not happy since my numbers have steadily been coming down for the last year taking Urso. Any thoughts? On another note Bili Direct raised from .0 to .1 both before and after so that's not good.

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shadowme2
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27 Replies
shadowme2 profile image
shadowme2

I guess I can't do math anymore either lol. It was an 8 day difference, not 10.

ninjagirlwebb profile image
ninjagirlwebb

As with any blood work there can be sporadic fluctuations. The thing to look for are trends over longer periods of time. If you have an increasing slope of data points, think your doctor would note that.

Even people without pbc can have elevated numbers every now & then. It is only if it is consistently upward trending that will raise red flags for further investigation.

7443jec profile image
7443jec

I wish I understood all the abbreviations and numbers!!! My consultant sent me the results of 9 different blood tests but I don’t know what they mean. Apparently the AMA number gave the diagnosis of PBC. Ive got to wait until Oct for a fibroscan. Best wishes to you. X

mrspeffer profile image
mrspeffer in reply to7443jec

Go on the internet and look them up. All the information you need it at your fingertips. You will find out what the abbreviations mean, what the function of the test is and the ranges tested for.

EileenUSA profile image
EileenUSA in reply to7443jec

pbcers.org/about-pbc/tests/

Hope this helps!

7443jec profile image
7443jec in reply toEileenUSA

Many thanks, that looks very helpful. I will need to concentrate on it. X

Candy12 profile image
Candy12 in reply to7443jec

This is a good link to see what the tests are and what there for. It won’t give you the ranges, due to each lab having there own lower and upper range. The range for your particular lab, will be on the print out given to you by your doctor. Hope it helps a little.

labtestsonline.org.uk/

7443jec profile image
7443jec in reply toCandy12

Many thanks to you too, I will be making notes.x

butterflyEi profile image
butterflyEi

As ninjagirlwebb has said blood test results are best looked at over a longer term, I guess really the main thing is how are you feeling now?

shadowme2 profile image
shadowme2 in reply tobutterflyEi

I feel pretty good now, thank you! Turns out I had a dislocated rib that was poking a muscle in my back causing spasms. For those of us who have given birth the pain was that bad. Coming in waves just like contractions. Yikes. Well, it's spring in Michigan so I've been pulling a lot of weeds, planting gardens, mowing, ect…..wish I new the exact movement that caused that so I don't do it again. Going to therapy and it's helping. It's troubling though because when you're in that much pain it would be insane to turn down any pain medication but you also don't want to hurt your liver. Oh well onward and upward. Lot's more work to do.

mrspeffer profile image
mrspeffer

Good Morning....Hope this find you without pain and feeling much better. I have unfortunately experience severe muscle spasm, and there is really no way around them but to take the drugs. That being said, our little livers will suffer from them. The good news is that if you flush your system out, this will help get your numbers back in range. Maybe a lemon water drink or a daily detox tea will help this along. Anytime we use pharmaceutical and non pharmaceutical medications, there is a chance the enzymes will react. Give it some time, you will be back to your "normal" levels in no time. Be well

shadowme2 profile image
shadowme2 in reply tomrspeffer

Thank you, that is my hope! Drinking lot's of Kefir and eating clean. Well mostly hah!

danaLL profile image
danaLL

I would asked to take labs again in two weeks and see if they go back down. That should be enough time. And you know going forward hi Pam And I’m not kind to your liver, but your numbers are so low that I wouldn’t worry even after a spike. Thank you for posting, I always try to figure out how different things impact my body with blood test as well. It’s helpful to see what happens with others

shadowme2 profile image
shadowme2 in reply todanaLL

I guess I'm more concerned about the Bilirubin Direct rising more than I worry about the enzymes and alk phos….

danaLL profile image
danaLL in reply toshadowme2

I do you see your doctor knows Best but mine has shot way up and is north of 1.0 and I am still a six on the melds score, Which is the lowest possible rate I know asking my doctor about that score has helped take a lot of stress off. Which is the lowest possible rate I knowIt’s my understanding that bilirubin number moves the slowest.

shadowme2 profile image
shadowme2 in reply todanaLL

So you mean .1 not 1.?

Wishing the best for you :)

danaLL profile image
danaLL in reply toshadowme2

Unfortunately 1. My total is at 2

shadowme2 profile image
shadowme2 in reply todanaLL

In reading gwillis posts it looks like it's possible to improve that number?? I sure hope so, it's something to aspire to anyways….I guess I'll find out soon enough as I've again improved my diet and am getting plenty of exercise. But wait, I just noticed you said your total is 2. That is not extremely high...prob a dumb question but are you sure your doc is checking bilirubin direct?

danaLL profile image
danaLL in reply toshadowme2

The total is 2. They check indirect, direct and total

gwillistexas profile image
gwillistexas in reply toshadowme2

I’m told direct bilirubin is the most important of bilirubin levels. My dr watches that & ALP.

shadowme2 profile image
shadowme2 in reply togwillistexas

Yes the bili total I believe is how it runs through out the body, while direct is how it is specifically in the liver. As far as I know the range is 0.00 to 0.3. We don't want it to reach .3

Mine just raised to 0.1

Like all of us it's a bit tiring to always have this at the back of our minds but things could be worse. Hard to remember some days life before diagnosis. That free wheelin' spirit I used to have. Not complaining, just a thought.

gwillistexas profile image
gwillistexas in reply toshadowme2

My last hepatic showed direct 0.00 which surprised me. The one before that was 0.3.

shadowme2 profile image
shadowme2 in reply togwillistexas

Wow, I don't get it but we'll certainly go with the 0.00! That is a question I have...if you can improve that count or once it's high is it permanent. Either that .3 test was wrong or there is hope for improvement. Promising news, thank you.

gwillistexas profile image
gwillistexas in reply toshadowme2

I looked back at my labs. When I was first diagnosed my direct was 0.4. Once I was on Ocaliva it came down. I’ve had a reading of 0.1, 0.2 & 0.3 in the past. Looks like it can fluctuate a little.

shadowme2 profile image
shadowme2 in reply togwillistexas

A little? That's amazing! So glad to hear.

gwillistexas profile image
gwillistexas in reply toshadowme2

I’m scheduled to see hepatologist July 12th. It will be time for labs so we’ll see😊

ninjagirlwebb profile image
ninjagirlwebb

My hepatologist told me not to dwell on any one specific test result. The important thing is to focus on the trends over time. If you chart the data and see an upward trend, then it may be a cause of concern. On the US patient portals, you can trend and create graphs of your data by just clicking a button. So that is useful.

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