Do I have PBC: I'm 69 y.o and was... - PBC Foundation

PBC Foundation

9,477 members8,331 posts

Do I have PBC

12 Replies

I'm 69 y.o and was incidentally diagnosed with PBC 15 years ago following routine blood tests which showed 1:80 ama. I was prescribed urso 1500 mg daily. I refused to undergo a liver biopsy. I am still symptom-free and my LFTs still remain within normal range. Two years ago, I was confirmed as having Sjogrens. Symptoms are as yet restricted to xerostomia and xerophthalmia, so I'm not under medication. Antibody tests showed elevated ana, aca and ama 1:1280.

My question is should I continue with urso?

Read more about...
12 Replies
Ballymahon2 profile image
Ballymahon2

Yes

LMor profile image
LMor

Did you get diagnosed just by a blood test with positive AMA?

in reply toLMor

Yes. LFTs were normal and I had no symptoms at all, which remains the case after 15 years apart from an increase in AMA's

LMor profile image
LMor in reply to

I have positive AMA and smooth muscle antibodies and an enlarged liver and no one is diagnosing anything!! I have a fibro scan in April but from what I’ve read, that just detects scaring!! I’m so confused why I have to wait soooo long. I wish you well :-) x

in reply toLMor

Thank you...good luck to you too. I'm not overly concerned because I've seen absolutely no change in 15 years, so don't despair!

in reply toLMor

If you don’t have elevated LFT’s & Alk Phos, I suspect your fibroscan will be just fine.

LMor profile image
LMor in reply to

Thank you. I hope it is :-). My ultra sound showed an enlarged liver and slightly course texture so I am concerned as my antibodies point to Pbc and autoimmune hepatitis. I already have Hashimoto’s and I’m on levothyroxine

Ballymahon2 profile image
Ballymahon2 in reply to

An increse in amas would indicate pbc

Ktltel profile image
Ktltel

I would. It must be working. But, talk with your doctor just the same. 💟

I had positive AMA-M2 and elavated liver enzymes. After a year on Urso I am about the same, a little lower in my ALP but other LFTs in normal range. (Still positive AMA-M2)

Stella💟

Cladelol profile image
Cladelol

Do you have Raynaud? I’m just curious about your Ana, ama and aca. I have all three and I was diagnosed with PBC and Raynaud . Since taking Urso my LFT are fine 🤞🏻. I go on taking Urso

No, I don't have Raynaud. I've developed really cold feet, but they have a healthy colour.. so far! 😉

My Lfts were always within normal range despite high AMA's, which is why I'm not even sure I have PBC, or why I'm on urso. But I definitely have Sjogrens.

I hope you remain stable 🙂

Cladelol profile image
Cladelol in reply to

If you only have AMA positive and no Phosphates or Gamma elevated, then you probably do not have PBC. But you could possibly develop it as per having +AMA (specific PCB marker) but anyway if you feel okay try no to think on illness and enjoy life.

I’m symptom-free and hope to be like this for long. My only problem is dry mouth when sleeping but try to solve it with a tablets stuck on my gums and help me to sleep some hours without Dryness.

Not what you're looking for?

You may also like...

LFT's have returned to normal...do I still have PBC?

I was diagnosed with PBC back in Dec 2015 due to elevated LFT's, raised GGT and AMA of 10.5. I...
Hils67 profile image

Do I even have PBC?

Hi, this is my first post and it's not so much a question but a rant. I had my gall bladder taken...

PBC diagnosis??

Hi, I feel that I have been in limbo regarding PBC diagnosis and wondered if anyone could give...
Lammasue profile image

Hi there, what to do if you are only ama-m2 positive but have normal liver function test ?

Hi everyone. I'm very glad to find this place. It's really helpful reading the posts here. Sorry...

Diagnosed yesterday with PBC

I went for a health check at doctors as my blood pressure was a little high. Following blood tests...
Sammie6 profile image

Moderation team

See all
PBCCheryll profile image
PBCCheryllAdministrator
janethomas profile image
janethomasModerator
Cupcake1971_ profile image
Cupcake1971_Moderator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.