I feel that I have been in limbo regarding PBC diagnosis and wondered if anyone could give me some advice.
Following routine blood tests in 2007 (I was referred to a dermatologist as I had a rash on my legs) it was discovered that I had a positive AMA. I was referred to a gastro specialist and had a liver biopsy in 2007 which was negative. My specialist said he still didn't want to rule out PBC. I have had further blood tests in 2008 (AMA positive and LFT's normal) but in 2009 my blood test came back both AMA negative and LTF's normal. In July 2010 my bloods went back to AMA positive and LFT's negative.
I only recently went back to see my specialist in December 2012 (the hospital didn't write to me further and I didn't follow up) and I have had further blood tests and the specialist wants to see me again in four months. He is still convinced positive that I have PBC and wants to see what my blood tests show. I am not on Urso or any other medication. I thought with PBC as well as having a positive AMA I thought you had to have an elevated LFT’s and a positive liver biopsy? Obviously I am hoping my latest blood tests will prove to be negative and I do not have PBC, but if the AMA does come back as positive is it likely that I do have PBC even though my liver biopsy was negative? Apologies for the long message!
All the best.