Day 2 of Urso

[Lisamarie33]

After being diagnosed just over a week ago I am on day 3 of urso in the morning. So far I seem to be o.k but keep waiting for side effects to get me. I seem to have heartburn after taking the last tablet of day. Let's hope it works feeling hopefull.

[Hidden]

I have to take nexium with Urso. Urso works fast for me with heartburn the only side affect

[Lisamarie33 in reply to Hidden]

I have not heard of Nexium. It is only day 2 so will wait to see if it eases or goes away as I get used to it. If not I may see if I can take something.

[Hidden in reply to Lisamarie33]

I don't believe it gets better. You need to tell yur doctor. Nexium is a pill for heartburn

[Lisamarie33 in reply to Hidden]

If i continue to get it over next few days I will see doc next week. I guess its a small price to pay and could have far worse side effects.

[Lmur in reply to Lisamarie33]

Can you not take nexium while on urso I thought you could ??

[Lisamarie33 in reply to Lmur]

Not sure to be honest all new to me this.

[Ktltel]

Make sure you eat something with that last pill you take. It can help with the heartburn as long as it's not something super heavy or fatty.

Stella. ❤

[Lisamarie33 in reply to Ktltel]

Thank you. I am being super cautious at present making sure I eat something substantial when I take my pills.

[cazer]

i found that i had no side effects from urso at all. in fact i found it helped with stomach acid it was much improved. cazer. x

[Lisamarie33 in reply to cazer]

Heartburn seems to be the only side effect i have to report at the moment. Fingers crossed that's all I get.

[cazer in reply to Lisamarie33]

i was on it for 19years.... i have just had a transplant 3weeks ago..... and i think a great deal of how long my old liver kept going for is down to the urso.

i was a stage 4biopsy all those years ago and was told at the time that I would need a transplant within 5/10years....so i wish you all the best... with urso your pbc may stay stable for a very long time or indefinitely. cazer. x

[Lisamarie33 in reply to cazer]

Wow urso did keep your liver going for a long time after they said it would. Luckily I have no damage to my liver at present after every scan going. Fingers crossed I get many years of urso. I hope all went well with transplant and you are on the mend.

[cazer in reply to Lisamarie33]

thanks... doing pretty well really... in a bit of shock as I was only on the list for 6 weeks!!!!! and it was first call.

you may not with a bit of luck ever get to cirrhosis stage.... my best wishes to you. cazer.

[Hidden]

Hello Lisamarie33.

I got heartburn after starting the urso December 2010. I did get a few other initial side-effects but I do get heartburn from time-to-time.

I have found with the urso, it is best to take the final tablet not long after the evening meal. Works best for me. If you do get heartburn take a calcium with Vitamin D tablet (they are very cheap, I buy supermarket own brand, same active ingredients as our UK Rennies for indigestion and heartburn but much much cheaper), works for me.

I started the urso on 2 x 300mgs but a couple years after taking, the pharmaceutical co lost their licence for the urso so I had to have 4 x 150mgs. I take 2 with breakfast, 1 an hour after lunch and then the final one about an hour following evening meal.

I have read that you can take the urso when you feel as long as take the recommended dose per day. I have tried various ways myself and find what I am doing now seems better. I once tried it all at once after breakfast, boy did I start to itch a couple hours later, something I never do in spaced out doses. I itch anyway but these days confined to late at night but know that in my case I think though the urso improves how our biliary system is working now, it also causes the itch so one rules out the other but I don't feel I can take a high dose at one time.

[Lisamarie33 in reply to Hidden]

I am on 750mg. I take the smallest dose 250mg in the morning with breakfast. I take the 500mg with my evening meal. I am thinking of taking 3 doses instead so I will take x3 250g. I guess it's all trial and error in getting what works right for you.

[Hidden]

Are you taking the last pill of the day at or near bed time, if so you could try taking it a little earlier. I take my last one by 6pm with the evening meal.

[Lisamarie33 in reply to Hidden]

Hi I am taking my last one with my evening meal at around 6pm. My last one is the highest dose one 50mg tablet. I am thinking of just taking the 250g dose but 3 times a day.

[Hidden in reply to Lisamarie33]

Yes it may help to split the doses, i took it three times a day at the beginning and i think the patient leaflet does say three times a day for the first three months if I remember correctly.

Then in any combinations that suits you, some people take them all at once but i didn't tolerate that very well so I queried it with my consultant and she said she preferred me to stay with twice a day. I had some side affects at the beginning (8 years ago) but they were short lived. Hopefully it will settle down for you to.

[Lisamarie33 in reply to Hidden]

I think it is just the way the gp prescribed it to me. I should of just been given the 200 mg box but I got a 500mg and a 250 one. It does actually say on my box to take all at night but don't fancy that. So far so good symptom wise.

[Hidden in reply to Lisamarie33]

I have the 250mg, the dose to take each day is dependant on your body weight. If the 250mg suit you better because you can devide them up I would ask your GP for those your overall dose to your weight is the important thing to have right.

[Lisamarie33 in reply to Hidden]

My gp has adjusted my prescription for next time so I can take 3 a day. Going to use what I have for now as I have paid for them.

[liver-bird]

I always take mind after food and have had no trouble at all ☺

[Shulsey]

Im supposed to take Prilosec for a ulcer I have. It's much like Nexium. I do not take it though because it's a over the counter med that is somewhat expensive & my insurance will not cover it.

[58goose]

It says 'take with or after food' on my Urso prescription and as long as I do that I have no side effects. I take them in the evening when I have my main meal.

[Lisamarie33 in reply to 58goose]

I split my dose up today so took 3 tablets instead of 2. No heartburn tonight.

[Quilter1]

Take mine with breakfast & evening meal, been on them 4 weeks now with no side effects