PBC Foundation


Wondering if anyone has been put on this drug, it's from a study regarding Opiate Antagonists. I suffer horrendous itch 90% of the day and night and only sleep when I take zopiclone which I admit I am probably addicted to now.

Any info from someone who has used it would put my mind at rest one way or the other.

You used to have to go into hospital on a drip with it first to slowly administer it but that has been deemed unnecessary now as long as you stagger the dose correctly.

Look forward to hearing from you.


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Hello scratty.

I thought I had seen this mentioned some place else so after having a snoop about I have managed to find a posting that appeared on this site 2yrs ago now and cioncidentally I responded to the posting. If the link doesn't work feel free to re-post so. I put 'naltroxene and PBC uk' into the Google, was the first that came up.



Hi . I was on it a few years ago but it really didn't agree with me. ... found it very heavy to deal with. But that's not to say it won't agree with you though. ...

I use rifamplin for my itch and have found I have responded best to this with the least amount of side effects . Hope you have relief soon what ever works stick with it ..... :) X


Thanks for the replies lynda and peridot, I'm going to give it a go, I've tried everything else so fingers crossed. I'll let you know how I get on.


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Hi I also was put on it but I didnt respond well to it. I am now on rifampacin & find it better to deal with & it has certainly helped with the dreaded itch, take care x

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