Hi everyone, I'm new to the forum. I'm very confused about how to definitively diagnose or rule out PBC, and AIH. A recent yearly physical revealed my ALT liver enzymes were at 98. Doctor said it could be anything, including pbc. He ran an AMA antibody test hat came back negative today...and said you don't have autoimmune liver disease (by the way, I am female, middle-aged, and already have another autoimmune disease--Hashimoto's Thyroiditis). I told him that I read that roughly 10 % of individuals may still have pbc despite a negative AMA test. He then said yes but, your ALP is negative, it is just the ALT which was elevated, therefore no biopsy. Is this sufficient, and should other anti-body tests have been done to rule out auto-immune hepatitis.
In nutshell, I'm asking what needs to be done to rule out autoimmune liver disease...all types of it.
Thanks for your help!