PBC and AMA negative... how many of you are out there?

[amandarosas]

So I know the research says, most 95% of people with PBC are AMA +......but what about the ones who are negative?? How did your Dr diagnose it? Also what about LFTs that are only mildly elevated?

[KarenRL]

You and I have already talked about this, but just for the rest of the forum's benefit, I'll go ahead and chime in here. I am AMA negative and the only thing off in my blood work is mildly elevated ALT (fluctuates between 60-80). Therefore, I was diagnosed via liver biopsy.

[amandarosas]

Karen, u have a AMAZING Dr for him to recongnize PBC from a mildly elevated ALP! I know have a great Dr, but before him every damn Dr told.me it not not even possible to have PBC with a ALP of only 100.

[amandarosas]

Oh and ALT, mine is 70 but i have another test this friday

[Cherwash]

I am AMA negative, but my ALP was at the highest 600, since beginning Urso, it is now down to 170. My liver bipsy confirms PBC, had 2 liver biopsies, one year apart and both confirm PBC. Still trying to figure out AMA positive vs AMA negative??? Good, bad, doesn't matter????

[amandarosas]

What exactly did ur biopsy show?