Hi, I have AIH/PBC overlap and one of the questions that has been bugging me is " could this thing be genetic?"
I have not seen or heard from my father since I was 3 years old (50 next month) and no one on my mum's side of the family can ever recall anyone with any kind of liver disease so me and my brother decided to find him because he is worried about me and we both needed answers.
Now according to my father, he had twin sisters and in 1956 one of his twin sisters died at age 17 due to liver trouble. He said that back then nothing much could be done for serious illness and unfortunately she died....he asked why so I told him everything. I met my two sisters who I had no idea existed and told them to get checked out for AIH/PBC and so far one of them has AIH.....she said she thought she was healthy.....she has had no trouble except some tiredness but she has children and put it down to running around after them all day.
It makes me wonder how many of us have other family members with either or both of these conditions.