B12 patches: I’m on 3 monthly... - Pernicious Anaemi...

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B12 patches

Mag999 profile image
23 Replies

I’m on 3 monthly injections after losing my nerve with self injecting. I now realise I do need more so was looking to buy ampoules but saw patches on Amazon which have good reviews. 1200mg methylcobalamin plus folic acid.

has anyone tried them? Opinions?

thanks

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Mag999 profile image
Mag999
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23 Replies
wedgewood profile image
wedgewood

Yes, I have tried them , but they were useless for me . I’ve also tried mouth and nose spray , sublingual and normal tablets . Injections are the only way that I can benefit from B12.

I have confirmed a Pernicious Anaemia diagnosis ( positive Intrinsic Factor Antibodies test ). You could try them , because I have read on this forum , that some members say that they benefit from them.

A scientist on this forum said that the B12 molecule was too large to permeate the skin.

Why not try some numbing cream before injecting , if that’s what’s bothering you .? ( Amazon ! )

You can also inject subcutaneously with a very short needle. This method is often chosen by patients who don’t like the long needles which are used for the I.M method !

Best wishes !

Mag999 profile image
Mag999 in reply towedgewood

Thanks I won’t waste my time with them then. I haven’t tried sub cutaneous will look into that. I can do im but I got a nerve I think and got some numbness and it freaked me out.

wedgewood profile image
wedgewood in reply toMag999

It’s probably a once in a million event . Try not to let it put you off . It’s never happened to me in 10 years of injecting weekly. I once had a big spurt of blood that shot across the room , but it stopped immediately by pressing on it for a minute or two . That was my worst experience !

Nackapan profile image
Nackapan in reply toMag999

I've done subcutaneous b12 injections for about 4 years now. I do thsrs at home with a 30G 1/2 needle .27-30G suitable

I also have IM at the surgery every 6 weeks .

I've found little difference .

Always a little disappointed IM don't last longer than sc

In theory they should.

Myoldcat profile image
Myoldcat in reply toMag999

I had intramuscular injections at the doctor's surgery, and think I would struggle to do them myself. I inject subcutaneously and it's much less uncomfortable, plus I have a good choice of areas well padded with belly fat! Who knew it would come in so handy 😄 Dr Klein recommended patches for my hubbie who doesn't have PA but slightly low B12. We're awaiting his next blood tests to see if they've had any effect, will post results.

Noelnoel profile image
Noelnoel in reply toMag999

Even my woosiest husband has been si. If he can …

When Dr Klein gave him the needle to do his first self inject and he did it, I could’ve fallen off my chair. He been doing it ever since. The SC needle is tiny

Nackapan profile image
Nackapan

I've also tried high dose oral.Sublingual sprays .

Don't work for me .

Technoid profile image
Technoid

Placebo only.

Some research happening on technologies which would create viable ways to deliver B12 through skin patches but afaik, haven't reached the market yet.

EllaNore profile image
EllaNore in reply toTechnoid

It would be nice if they could develop a patch like an insulin patch that would deliver the B12 deeply into our tissue.

Technoid profile image
Technoid in reply toEllaNore

It's technically possible with nanofibre patches, see this research :

pubmed.ncbi.nlm.nih.gov/366...

Would definitely be more convenient right!

EllaNore profile image
EllaNore in reply toTechnoid

That looks promising. 🤞🤞🤞

tomdickharry profile image
tomdickharry

I tried them but they did nothing for me. Liquid B12 can work if you take massive amounts, like 25000µg a day. Some split it into small amounts but I took it all in one go with water. It's passive absorption but you only get a tiny percentage of it.

It's mostly methylcobalamin so take it early in the day as it can interfere with sleep.

Amazon and eBay both used to have it.

Mag999 profile image
Mag999

thanks very much for all your help, will try subcutaneous injection

B12again profile image
B12again in reply toMag999

I don’t think in terms of SC or IM. I use 1ml diabetic syringes with fixed 13mm 29G needle, I fill the syringe then jab straight into thigh or arm, not thinking about angles of entry. 1 needled/syringe and 1 ampoule, job done. I’ve had no problems with this, the needle going in is painless and just some stinging of fluid going in which is to be expected. Good luck, you can do it, it’s just the fear that’s your enemy.

donnabrain profile image
donnabrain in reply toB12again

The fluid won't sting going in if youA) push slowly and B) warm the ampule a little before use( I pop mine in my bra for 5 mins)

Cornwaller profile image
Cornwaller

I tried patches and they did little. Here's something I don't get, b12 is bright red, so why aren't the patches red before, after or during use, nor does the skin get red?

B12phd profile image
B12phd

Ask your Dr. for insulin syringes and needles. B12 does not have to be injected in deep muscle. It must wad in the early studies and so they haven't done anything different. Shallow injection actually slows absorption and excretion, allowing more of your dose to be absorbed. I've been using them for years. Easy to self inject with them.

phoenix80 profile image
phoenix80

I've tried them, and definitely felt the same calm feeling that I get after a jab. Not sure if that was the B12 or something else in the patch. I tried the ones without folic acid. They do seem to help me a little

Hockey_player profile image
Hockey_player

My husband does my injections into my arm. Do you have someone who could do your injections for you?

Mag999 profile image
Mag999 in reply toHockey_player

You have a very trusting relationship🤣

I wouldn’t let my husband anywhere near me with a needle, he isn’t very empathetic when it comes to other people’s pain. He’s lovely really just not with medical/ first aid stuff

B12life profile image
B12life

where do you inject?

Mag999 profile image
Mag999 in reply toB12life

In my thigh muscle, I’m going to try sc in my stomach.

Oneash profile image
Oneash

Are you using fine enough needles? I use one thick one to draw up the liquid and swap to a fine one, making sure there is no air in the dose. If you pull the skin taught, between finger and thumb, then place the needle tip against your skin, avoiding any pores, as you let go of your skin, you find it springs onto the needle. Then let it go in as far as you are comfortable with. Just making sure you don't move the needle from side to side as you press the plunger and remove the needle.

Swab before and after.

I'm usually so wanting my dose, I don't fret about the slight pain.

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