I have probably had b12 def since I got really ill 43 years ago, but kept taking B complex and so all testing failed to show a problem. I had my first diagnosis of macrocytosis in November, despite the B complex, maybe because I was trialling a high B1 protocol (via Elliot Overton's work). In December I got so ill that I decided to take hydroxyb12 sublinguals whilst waiting for an appointment with a haematologist. The antibody tests were both negative. I added a multivitamin and general B Complex.
I cannot tolerate B12 orally in megadoses - 1mg every other day leaves me too ill to function - weird gait, leg pain, nausea, extreme depression, shortness of breath, increased tingling, burning pains and pins and needles, weakness and exhaustion mainly. I tried HomocysteXPlus by Seeking Health and cannot tolerate that either. I was supposed to have a hydroxyb12 shot tomorrow, my first.
Last night I read that people with ME/Chronic Fatigue Syndrome, one of my many diagnoses, often cannot tolerate start up symptoms and need to go much lower dose and very slowly. This is counter to the advice to start injections and have them every other day at least 1 mg.
Have I misunderstood something? I have rescheduled the shot for next Tuesday but now not sure that I should not continue instead with the sublinguals but lower dose and more slowly. I have heaps of very concerning neurological symptoms, and cannot be sure the haematologist will treat me. The shots I can get are supposed to be 1mg weekly and "see how I go", but this doctor now specialises in something else and so I do not even get a consultation with him. I don't want to give them a try, find I cannot tolerate them and then find the doctor reluctant to allow me to continue.