Serum folate

[sueeaton]

Hello,

I have injections every 5 weeks now for Vitamin B12 deficiency.

My latest blood test showed that my serum folate had dropped from 16.3ug/L two years ago to 6.1ug/L now. My haematocrit is below the range, my MCV above and there is a marker on the latest test to note that MCHC is above range.

I think this indicates that I am developing PA. When I spoke to a doctor at my surgery about these results she suggested that I take folic acid. I thought that taking these supplements could "mask" the possibility of PA. She also said she would refer me to a haematologist.

I would appreciate advice on whether to take the supplements - as my husband does my injections (the surgery provides the B12) I can have them when I need them as we also have a supply we bought from Versandapo.

Thanks.

[fbirder]

Your folate isn't that low, so it shouldn't be a problem. But taking folic acid (400 mcg a day) should also not be a problem - and it would rule out a folate deficiency as being a problem.

If you take folic acid while you have an untreated B12 deficiency then it can mask one of the symptoms of the b12 deficiency (macrocytic anaemia). This is only a problem if you have an undiagnosed B12 deficiency and you have a doctor that believes macrocytic anaemia is an essential part of a diagnosis of a B12 deficiency.

Your doctor obviously knows that you have a B12 deficiency, so that doesn't apply to you. Taking the folic acid will not affect any testing for PA, but it might well fix your blood results.

[sueeaton in reply to fbirder]

Thanks fbirder.

I've been much more tired recently and noticed an increase in the burning sensation in my hands and feet.

Is there any "overuse" or time limit on folic acid? I will try 400mcg a day but wondered if taking it continuously is advised?

[fbirder in reply to sueeaton]

Women of childbearing potential are advised to take 400 mcg a day. So it should be perfectly safe.