B12 & Folic Acid and Anxiety - Pernicious Anaemi...

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B12 & Folic Acid and Anxiety

Chocolatelover15 profile image
26 Replies

I have suffered with anxiety and panic for a long time but since my loading doses of hydroxocobalamin and folic acid my anxiety and panic are unbearable. I just wondered if anyone experienced this and then started feeling better? I'm nervous to inject further and wondered if I'd be better waiting 2-3 months until my next jab like the NICE guidelines. I'm not sure if it's the folic acid or b12 injections causing this or maybe a combination of both but I need to get myself well. Please help

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Chocolatelover15
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26 Replies
Nackapan profile image
Nackapan

How much folic acid are you taking?Have you finished the loading doses at the surgery ? .

Anxiety and feelings of panic atd documented B12 deficiency symptoms asis paranoia.

I had this but knew it wasn't actual anxiety caused by stress and also knew the paranoia wasn't normal.

Your autonomic system is affected .

It will settle.

If unbearable get a short term prescription to see you through via G.p.

Keep up your B12 injections at a frequency you can either get prescribed or if self treating endure .

I got alot worse before improvements made.

TC

Chocolatelover15 profile image
Chocolatelover15 in reply toNackapan

I was taking 5mg of folic acid with each jab but I don't know if this adds to my anxiety. I don't know how often to take the jabs? I was doing EOD for 2 weeks. How bad did your anxiety get before it improved?

Nackapan profile image
Nackapan in reply toChocolatelover15

In my opinion if you are self medicating. Stop the high folic acid supplement .

5mg is s very high dose.

Ususlly short term prescription if folate deficient .

Are you deficient by a blood test .

We're your loadng doses prescribed?

Chocolatelover15 profile image
Chocolatelover15 in reply toNackapan

My folate was 1 and now it's a 9. My B12 was prescribed by a consultant. They said EOD but as I was experiencing such bad side effects he said go to once a week but I'm not sure whether to spread them out further?

Nackapan profile image
Nackapan in reply toChocolatelover15

Try and stick to once a week as prescribed. So you can reduce your folic acid snd see if that helps?

As your folate rising okay

Only you know how you feel.

In my opinion I woild reduce folic acid and not B12 at this stage .

You will presumably have a review with your consultant.

Ride the rollercoaster its hard I know.

Ouf of interest is this consultant private?

If not amazing an NHS consultant working with you.

Anxiety is very difficult to deal with .

Chocolatelover15 profile image
Chocolatelover15 in reply toNackapan

No it's a private consultant. The NHS didn't want to know. It's such a horrid rollercoaster. My anxiety has been just deliberating at the moment

Maldeerum profile image
Maldeerum

What form of folic acid are you taking? Methylfolate can cause symptoms of high anxiety in some people. If you’re taking methylfolate you might want to consider a different form. I hope you feel better soon.

Chocolatelover15 profile image
Chocolatelover15 in reply toMaldeerum

I'm taking 5mg of folic acid. Not sure if this can cause anxiety?

MrsTuft profile image
MrsTuft

I find that folinic acid doesn't cause me anxiety. Methylfolate would tip me over the edge!

Chocolatelover15 profile image
Chocolatelover15 in reply toMrsTuft

Did you have any experiences with folic acid? Did that cause any anxiety increase?

MrsTuft profile image
MrsTuft in reply toChocolatelover15

Yup - I can only tolerate folinic acid. And in moderate doses.

EiCa profile image
EiCa in reply toMrsTuft

I do much better with folinic acid as well.

Merlintabby profile image
Merlintabby

I'm also having problems which i believe relate to B12 deficiency but my GP doesn't want to know. Could I ask if your consultant is a haematologist or neurologist?

Chocolatelover15 profile image
Chocolatelover15 in reply toMerlintabby

Are you having panic and anxiety on folic acid and b12? Mine is a consultant

Merlintabby profile image
Merlintabby in reply toChocolatelover15

I'm having various neurological symptoms including anxiety but not yet on B12. Just wondering where to go from here as GP useless.

Chocolatelover15 profile image
Chocolatelover15 in reply toMerlintabby

I had a private consultation with Dr Klein in Cambridge

Merlintabby profile image
Merlintabby in reply toChocolatelover15

Thank you - I've heard good things about him. I wondered if you were a member of the facegroup support group run by the B12 society. They are very knowledgeable & helpful, particularly regarding folic acid & other vitamins they recommend taking whilst injecting.

Technoid profile image
Technoid in reply toMerlintabby

"They are very knowledgeable & helpful, particularly regarding folic acid "

From what I've seen posted here, I beg to disagree. Their "protocols" might be very specific but that does not mean they are correct or appropriate.

Chocolatelover15 profile image
Chocolatelover15 in reply toTechnoid

How do you know if they are correct? There's so many different protocols :(

Technoid profile image
Technoid in reply toChocolatelover15

I would just ask them the reasoning for and logic behind their protocols and then decide whether it makes sense as something to follow or not.

Chocolatelover15 profile image
Chocolatelover15 in reply toTechnoid

Thank you. They just say to push through and increased anxiety is a good thing and it will get better?

Technoid profile image
Technoid in reply toChocolatelover15

I mean, explain the protocol. How it was formulated, how the dosages and forms were calculated or decided upon. I could be taking arsenic and if someone said, "just push through", that doesn't mean its a good idea to push through.

ottolinebear profile image
ottolinebear

Folic acid supplements don't agree with everyone. I added an ounce of liver to my breakfast every day for six weeks, and then I took a course of folinic acid. Two other things helped me reset my autonomic nervous system and turn the corner on anxiety (which was more like terror) . One was getting into cold water (not something I wanted to do at all but now I'm hooked) and the other was some reiki/reflexology.

A1298C profile image
A1298C

Folic acid is synthetic and problematic for many people. Try a natural form of folate eg methylfolate (which might be stimulating) or folinic acid. Hydroxocobalamin is natural but can impact nitric oxide and blood pressure. Methylcobalamin may be better for you. But more likely the folic acid is the problem. If you have a MTHFR gene mutation you must avoid folic acid.

Oneash profile image
Oneash

Hi, sorry to hear you are suffering this way. I find Floradix good, a complex of B vitamins and iron from natural concentrates. It's a bit more digestible, just tastes of rusty nails.The other thing is sit, breathe and ask yourself is this real? I think as your brain mends all sorts of crazy connections link up in your head. It's scary when you think you are going a bit mad, which then stresses you more. The brain needs calm mental exercises, calm space, nature walks, to get it fit again. I currently find if I get really stressed about something, it's like the hormones can't clear from the system, and I get disabling headaches. Best to just stop and give yourself a break.

Big hugs. You are on the mend.

PlatypusProfit8077 profile image
PlatypusProfit8077

hello, just checking in to see how you’re going? Did your anxiety improve at all? What did you end up deciding about your treatment schedule?

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