Pernicious Anaemia Society
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My diagnosis is a b12 metabolism disorder although my Nan did have a definite pernicious anaemia diagnosis. I have been self injecting alt days methylcobalamin at the recommendation of my neurologist and haematologist for a couple of years now. Plus having 6wkly hydroxo at the GP. Prior to this I had severe neuro pains and numbness in hands and feet that had been under control for over a year now.

My question is that recently I have had x2 courses of chloramphenicol for eye infections and have noticed a return of neurological symptoms to my hands and feet. I also am feeling run down and fatigued. I was wondering how long it would take to get back to normal. Does anyone have any experience of this?

6 Replies

Thanks clivealive that seems to imply it will be shortlived. I will go to my GP for a check up.


Please do - it may mean you need additional B12 injections and ask to have your Folate level checked as Folic acid works closely with vitamin B12 in making red blood cells and helps iron function properly in the body .

I am not a medically trained person but I've had P.A. (a form of B12 deficiency) for more than 45 years.

I wish you well


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Thanks clivealive that is most helpful.



I had chloramphenicol drops for an eye problem and had a severe allergic reaction. I later discovered that certainly the oral tablets are not advised with pernicious anaemia but even the drops affected me. took a week or two to get over it.


Thanks Gillsie54 I am hoping it will soon be out of my system!


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