Hi everyone I have a question, I have been taking 15000 mcg of Jarrows B12 under the tongue for 5 months as I have enlarged red blood cells, folate ok, dreadful fatigue originally diagnosed as ME/CFS. Such low blood pressure that when I stand up I have a sharp pain in my head, heart pounds off and I am dizzy and faint. Muscle twitches and jumps when I am trying to sleep, lots of ectopic heartbeats, stomach issues, peripheral neuropathy in my feet and top of head, strange walking gait and very wobbly walking. Cannot walk far.
My doctor will not treat me even though I have enlarged blood cells and do not drink or a vegetarian as my B12 6 months ago was at 660. I also have an underactive thyroid which was getting worse though in range at 3.90 I had been left on 50 mcg for 18 years.
When I first starting taking the B12 10,000 then upped to 15,000 I did start to feel a little better, now I feel back to square one, if there any of you out there that take more than 15,000 mcg's of Jarrows? am I ok to up it even further?
Katherine xX
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Katherine1234
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I took 5 mg of Jarrows Methyl B12 orally daily 2006 to January 2017. It fixed the peripheral neuropathy that I developed in mid 2005. When my neuropathy recurred in January 2017 along with a few central effects (loss of sense of smell, balance disturbances, brain fog, memory problems, tinnitus), I didn't try increasing the oral dose, but switched to injected hydroxocobalamin. This article confirms to me that I made the right decision.
Thank you Martin for your reply. I cannot get my doctor to sanction B12 injections and I have tried several times, even though I have enlarged blood cells, hair fulling out, dreadful low blood pressure 80/59, tinnitus that is a contant brain buzzing in my ears. The worse I feel the worse the tinnitus is. Fatigue is bad. I normally have a very high IQ but now my brain feels like it's not working, it feels like I have adult ADHD. I know I could go the self inject route and find a nurse or someone to show me how. I am screamish about this and have not plucked up the courage to do this.
Hello KimberinUS I don't have my results in front of me at the moment but all those ones MCV and others were flagged high over range. I had a high IGA over range too, folate and ferritan were in range. I don't think I had alkaline phosphatase, I will look later...I am going to ask doctor for more blood tests as I have upped my levothyroxine from 50mcg to 75mcg and now 100 mcg...I had high cholesterol and when my tsh levels go over 2 I get high cholesterol.
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Should I be getting more B12 injections?
Should I increase frequency of b12 jabs?
Cause of b12 deficiency? Should I get private bloods?
Shall I start taking 1000mcg lozenges, or should I give it a bit longer? 
