Pernicious Anaemia Society
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Stinging hydroxycobalamin, help with supplier or lidocaine advice?

This is my first few SIs of Hydroxycobalamin from Intravita. I'm sure my technique is fine but when the substance is being given its really excruciatingly painful that I can hardly bear it. I've warmed it and inject very slowly.

Can anyone offer advice on how to use lidocaine with this and how to do that or where to get Hydroxycobalamin that won't sting so much - I understand that it does sting but this is really unbelievably painful and I'm not whimpy about injections or blood taking usually!

thank you very much for your thoughts and opinions,

Gill

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Hi Thurgolady. Hmm...never purchased hydroxocobalamin from Intravita so can't really comment on 'stinginess' for that particular product. The excessive sting may be due to excipients (the inactive substances used as a vehicle for the B12) that you may be sensitive too. Or not...no real way of knowing. But this is more likely if you haven't experienced this with other brands of hydroxocobalamin.

It's not a good idea to use lidocaine, especially if you inject on a frequent basis (topical application enters the system and too much can be harmful). Lidocaine cream or a patch would only numb the surface of the skin: it wouldn’t penetrate far enough into the muscle (IM injection) or subcutaneous tissues (SC injection) where the stingy is occurring, so there would be no beneficial anaesthetic effect via this route of application.

injection with lidocaine should only be done by a suitably qualified medical professional. On a side note, injections of lidocaine can be quite painful (it’s very very stingy) and it's only used when the pain of a procedure exceeds that of the injection (i.e. for stitches or minor surgery).

Lidocaine is sometimes used when injecting very painful medications, but this should only be done by a medical professional. (It can also be used as a drug to treat cardiac arythmyia - but that's a different story).

Also - lidocaine can have some quite nasty side effects, more especially if used regularly, and there are contraindications to its use.

Here's more information about lidocaine:

everydayhealth.com/drugs/li...

Injecting hydroxocobalamin can be a little stingy (as you recognise) but if it’s so incredibly painful, then this brand is perhaps not for you.

Other reliable sources for hydroxocobalamin used by forum members:

mycare.de/en/suche/hydroxoc...

versandapo.de/en/substance/...

Both sites have English translation pages, accept PayPal, and deliver quickly. Products have long use by dates.

I've purchased from both and never had issues with delivery, product quality, or excessive stinginess 😉.

Good luck.

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I would get your B12 from another source.

The stuff from Intravita is, according to the owner of the company, not for treating medical conditions: healthunlocked.com/pasoc/po...

Gods know what other junk it has in it. As it is not a medicine it is not subject to the stringent legal controls you would expect from an injectable.

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Thank you fbirder. I have asked for the other ingredients as they are not stated on the bottles and no other information. But this company was recommended with a link to the actual B12 to buy from the B12 charity.

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Which B12 charity? It would be interesting to know who is advising people to buy non-medical B12.

Even more interesting to know why they recommend them.

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Thank you Foggyme, that's very useful.

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It looks like I need to try a different brand and will have a look at those links. I have heard of diluting hydroxy, is this possible with this and how and with what? Thank you, Gill

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Hi Thurgolady. Not sure what you mean about 'diluting hydroxy'.

Wouldn't suggest adding anything to hydroxycobalamin...it should be of a quality and standard to inject without additions...and without excessive pain.

It's a bit worrying that the ingredients are not stated on the bottle and that a patient information leaflet is not provided.

I note your use of the term bottle: hydroxycobalaim usually comes in single dose glass ampoules - sealed and sterile. If it's arriving in a bottle - bit worrying.

I wouldn’t use it.

👍

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I'm not concerned about the quality - its a single dose in a bottle (tiny) with a metal top which is just a different way of doing it than an ampoule and the source was recommended by the B12d charity so its fine, its a reputable company.

I've heard somewhere that you can dilute with sterile injectible saline and I was hoping to find out more about this but i understand what you're saying and thank you.

I think the PIL is missing because its done through the B12d charity although I bought it myself.

Thanks,

Gill

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Thurgolady. Just to clarify...the b12d charity is not connected to the Pernicious Anaemia Society (who sponsor this forum).

Irrespective of how you acquired the hydroxocobalamin, the provision of patient information leaflets and information about contents is a required standard for all injectable grade substances.

A bottle with a metal top does not inspire confidence as to the quality and sterility of the contents.

The best advice from this forum is not to use it (as per replies in this string).

Sorry if that's not what you want to hear.

👍

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Like Hidden says, a PIL is only a requirement for injectable medicines. But Intravita make a point of not claiming any medical use for their B12, indeed, they actively deny it can be used to treat a medical condition.

By doing this they manage to avoid all those cumbersome regulations that control the safety and quality of proper medicines.

Are these the actions of a reputable company?

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I had a similar experience with ampoules purchased from Sharm el Sheik whilst we were on holiday 3 years ago. Once they were all used up I purchased from Versandapo and have to say the ampoules from Germany are virtually painless in comparison.

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Thank you everyone, your thoughts are much appreciated.

Gill

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Perhaps not relevant, but I receive my B 12 injections 3 monthly at my doctor's surgery, and they always hurt like hell!

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Ask your nurse for bum injections instead of anywhere elsr and to do it slooowly.

Bum muscles are least painful and if done slowly it reduces pain significantly.

My own experience of having it done by others and myself.

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Thanjs for your reply, but they will only do it in the upper arm. I have learnt to relax the muscles and put up with it, as it only lasts seconds 😕

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