I normally self inject with B12 injections in UK which are water based. I read on here yesterday someone saying that the injections which they buy online are in oil suspension rather than water based like here in UK.
I need B12 which is water based. I assumed all B12 was water based and had never heard of oil based until yesterday. Can I buy water based online ??
Are the injections you buy online from Versandapo (which is the only place I know to buy from online) water based or oil based (In oil suspension) ??
Has anyone purchased B12 injections online which are water based ?
Thank you to all on this site as you've been very supportive and helpful.
Written by
Ryaan
To view profiles and participate in discussions please or .
I get mine from Amazon in Germany and they're water based. If you're a member of the FB group 'pernicious anaemia/B12 deficiency', theres a link on their files page which will take you direct to the B12 product.......
Yup. It was a presentation at the PAS conference last year. It showed that an oil suspension was absorbed much more slowly than an aqueous solution. Slow enough so that you could keep levels hig with less frequent injections.
The same person mentioned that they were planning on mixing hydroxocobalamin and methylcobalamin in a custom blend, for people who respond differently to the two types.
I did some looking afterwards and it didn't seem to be that promising (difficulty with pain at the injection site, IIRC).
" Dr Willemina Rietsema, in the Q & A at the end of her PAS conference video, explains about 'Vitamin B12 Depot - 'Depot' meaning it's suspended in oil so that the B12 spreads out more slowly through the muscle and, apparently, is more effective than water based B12.
She also said there are oil tablets and it's a good idea to use both injections and tablets."
I would think that if the brand doesnt mention depot, it is water based?
I've checked on Versandapo.de site, it says depot on their B12 injections but they're not oil based, they're water based.
I sent them an email to ask just to make sure. They said they're water based. (sorry I refer to them as water based as I don't know what's the correct term). I think its aqueous.
Ryaan Yes, the stuff from Versand is dissolved in water. Yes, it is described as 'depot'. All 'depot' means is an injection that does not go directly into the blood. It doesn't have to be oil-based.
I buy Rotexmedica 1000ug in 1ml water hydroxocobalamin.
I get 100 ampoules at a time because it's cheaper per ampoule and the postage is the same for 10 or 100 ampoules.
Interesting, I'v never come across oil based B12 injection. To your question VitaminB12Direct provides a water based b12 suspension and they ship to addresses in Europe if you have an address in continental Europe. Hope that is of use to you.
Fair enough, you have to stay in your comfort zone with these sorts of things for sure. To it's credit B12Direct does work exclusively with GMP certified facilities and tests product batches for safety at an independant lab in Canada for safety and potency. Sincere thank you for the heads up on this German outfit, that is interesting, I'll check out their prices, sizes and there protocols.
An intramuscular injection of a drug that gives a slow, steady release of its active chemicals into the bloodstream. Release of the drug is slowed by the inclusion of substances such as oil or wax."
These are preparations which are administered once with doses that is designed to be released at programmed release for a desired period of time.Usually they are administered as implants, they may be formulated with biodegradable or non biodegradable polymers. Dr.T.E.G.K.Murthy
You're right, in theory that's what it means but oddly for B12 depot just means an injection which doesn't go straight in to your blood like Fbirder explained.
The term Depot is mostly used for injections given to people with psychological/mental illnesses. That's what google told me and Google likes scaring people.
The B12 is not slow release because it's in water based solution. If you find it in oil based solution then it would be slow release and you would have to inject less frequently. The depots you're on about is the ones given to people with mental health issues, those are slow release oil based not B12.
I think water based is better because your body gets rid of what you don't need through urination, that's why you sometimes have a change of colour in urine (greenish) and I think you would have more side effects from oil based as it's much harder for your body to get rid of the excess.
It will be like injecting steroids. I think that's why steroid users (body builders) have bad acne on face and back so there is a plus side to water based, and it's much safer.
When I started injecting B12 I did get quite a bit of acne on forehead but I think the body is now used to it and might sometimes get the odd spot or 2 but nothing compared to the painful bumpy horrible spots I first got for few months.
My wife stopped injecting because of horrible facial acne but I chose to continue as my symptoms were far worse and I couldn't carry on with normal day to day activities and chose to live with spots father than those horrible symptoms, I became almost totally inactive and kind of bed ridden. I know have to deal with the fatigue but back to almost normal life.
My symptoms were a long endless list and now only a few.
My vision became quite bad and couldn't even drive at night or in sun with low B12 but after injections I went back to my optician 4 yrs after my last test and I never wore glasses and my vision was much better, my optician was surprised.
Horrible thing B12 deficiency.
When I was first prescribed B12 I had never heard of it. My first thought was what good is B12 going to do !, but after a few months there was a huge improvement.
If you tell anyone you have B12 problems they kind of shrug it off but it's a silent and slow killer.
Sorry about the long reply. I hope things work out for you and if your GP doesn't do much like most I suggest you self inject once a week for about 12 weeks it will kind of give you an idea of how much it will help you as some symptoms are irreversible.
What helped me most is B12, Folic Acid, vitamin D but I think I'm low on Iron hence the fatigu. I'm going to have a blood test and see where my iron is at.
These 4 things I learnt are life changers and should always be maintained, they're crucial for your health, they can make you terribly ill as I have learnt (the hard way).
It is not the medium but the route that makes it a depot? Any IM (or SC) injection will be slow release compared to a non-depot injection straight into a vein.
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.
B12 injections 
Where can I buy B12 injections
Stopping b12 injections 
