I developed mild sensory neuropathy about 3 years ago. Mostly permanent pins & needles in feet, occasionally hands, with occasional sharp stabbing pains in feet. Many tests. Spinal scan revealed no significant abnormalities. Nerve conduction studies revealed sensory & motors responses within normal limits. Nutritionist said diet fine. I have IBD but gastroenterologist doesn't think I have an absorption problem. Some B12 deficiency in older relations. Diabetes runs in family.
Original testing in 2014 B12 was 203. They said it was normal range. But I insisted and got loading doses but only the 6 i.e. the regime for no neurological symptoms. The stabbing pains went away but symptoms had not stopped importing when loading doses stopped. Since them 3 monthly maintenance doses.
Lately noticed pins & needles progressing from feet up lower legs. Also in last month.stabbing feet pains have returned. Full blood test results 31.3.17:
Total Vit D (serum) 100nmol/L (>50.0)
Serum folate (42U5) >20.0 ng/ml
Serum ferritin (XE24r) 50 ng/ml (20.0 - 350.0)
Serum B12 level (XE2pf) 1201 ng/1 (200.0 - 960.0)
White blood count 7.9 10*9/l (4.0 11.0)
Red blood count 4.53 10*12/l (3.5-5.5)
Serum TSH (XaELV) 2.69 mlU/L (0.3-5.0)
Plasma fasting glucose level (44g1.) 5.7 mol (3.3-6.0) Doctor said I may be diabetic within a few years.
There are lots of other blood cell things, but not sure how relevant it is? All in normal range.
The doctor is now saying that B12 is normal so didn't need more loading doses with neurological regime. I asked him to consult haematologist. He said today "I've spoken to haematology and
- they can see no logical reason from results why Vit b12 could be causing further neurological problems
- however they admit this is still a grey area and no conclusive proof from studies either way
- there is no actual harm in having a further 3 week loading dose as discussed.
Therefore given our previous discussion I'm happy to support a further 3 weeks of 3 times a week injection (9 in total)" I had said to Dr I thought pointless testing serum B12 since I have maintenance doses.
So I will get more loading doses but they don't seem to think B12 is the issue. I spent quite a lot of last night awake with pain/discomfort in feet. Can any one please give any advice. I am worried about my symptoms.