I am new here. I have recently developed neurological symptoms (pins and needles, numbness, cold sensations), particularly in my hands and feet, although occasionally in other parts of my body such as legs. I am a vegetarian who eats dairy products and I have Rheumatoid Arthritis and take weekly folic acid supplements as I have been on methotrexate for over 20 years. I have other symptoms such as IBS, constant UTIs, psoriasis on my scalp (and sores in my nasal cavity) and a slightly sore tongue, which made me think I possibly had B12 deficiency, although no-one in my family has pernicious anaemia. I had a blood test last week which shows a B12 serum level of 228.0 ng/L (i.e. normal range), a serum folate level of 8.40 ug/L (i.e. high), a haemoglobin concentration of 111 g/L (i.e. low) and an MCV of 78.7fL (i.e. low).
My GP agreed to prescribe hydroxocobalamin injections (5 doses on alternate days, then one every 3 months); but do you think this sounds like B12 deficiency, and, if so, should I be having more injections until symptoms improve, as per NICE guidelines? Also, how soon would the injections begin to take affect? I think my neurological symptoms have improved since being on the injections (4 so far), although now I am tired at the end of the working week, they seem to 'kick off' again.
I have not had the Serum MMA or Homocysteine blood tests, as I have already started the B12 injections and apparently this can affect the result and deliver a 'false normal'.
I would appreciate any advice or guidance about this (sorry my post is so long!).