Buying b12 injections

[MCMC]

Can anyone recommend, where to get b12 injections on the net.

[Hidden]

You should read the PAS forum, start with this topic:

pernicious-anaemia-society....

[MCMC]

Has anyone used to this site?

apotheekverschaeve.be/NL/pr...

I can't get my nexus to translate the language on the recommended site, but it will for this site above.

[harrystiles99 in reply to MCMC]

yes superb service I ordered on Tuesday and they sent it 24hr delivery to the uk and I received it today Thursday.

[Lila22 in reply to harrystiles99]

Hi what site did you order from? Thanks

[johnbarriesmith]

I originally used Cyanocobalmin from a Canadian site (in vials) but shipping charges were very expensive , I tried in the UK but the GMC demand a prescription , so I had to resort to the net Doctor service which costs £25 / year ,

but you will have to provide evidence of your diagnosis .

[Erainy]

I suggest contact the charity B12d.org and ask where you can obtain Methylcobalamin vial.

[MCMC in reply to Erainy]

I've looked on their site and it gives a link on eBay. The injections I looked at on the above site I posted a link to, seem to have more b12 in them.

Regards MCMC

[Erainy in reply to MCMC]

ebay site? You mean the Paypal donate button? That's for donation if you wish to donate to the chrity. You need to email them if you are looking for methylcobalamin vial.

[MCMC in reply to Erainy]

No the link too me to eBay page, selling b12

[Erainy in reply to MCMC]

OK, never mind ebay page. Did you contact them? They just sent me a vial.

[Erainy in reply to MCMC]

I think your browser is hacked or infected. It doesn't go to ebay site.

[Erainy in reply to MCMC]

Your website links to a page for 3 ampoules which costs 8 Euro, I think that's expensive considering you have to pay postage and possibly import duty.

Anyone interested in obtaining free Methylcobalamin can contact the UK charity link I posted above.

[B12Turbo]

Hi MCMC

You should find here in Britain, that Cyanocobalamin is freely available from any pharmacy without a script, just ask for Cytacon Cyanocobalamin, this is the only fully licensed product I know of and costs £ 11.23 for 50 tablets X 50 micrograms per tablet.

[Hidden in reply to B12Turbo]

But it is no good at treating B12 deficiency at such a low dose. Would need to take at least 500mcg preferably more as only 1% gets through via passive diffusion. Even then, many people get no relief whatsoever from B12 tablets. Here is a very old study showing that low dose cyano only keeps people at low serum levels of B12 and does not replenish body stores:

ajcn.nutrition.org/content/...

Those tablets would only be useful for someone who had absolutely no malabsorption issues of vitamin B12. They are not meant for people with classic PA or other malabsorption conditions. This is also made very clear in the NICE guidelines:

cks.nice.org.uk/anaemia-b12...

"Be aware that oral cyanocobalamin is suitable only for the small number of people with proven dietary deficiency of vitamin B12. It is available on an NHS prescription only for a person who is a vegan, or who has a proven vitamin B12 deficiency of dietary origin, and the prescription must be endorsed 'SLS' (Selected List Scheme)."

Since most people using this forum have PA or similar I thought it would be important to point this out.

Hampster

[B12Turbo]

SO Sorry Guy's

This morning I committed the unforgivable medical sin, rushing out, I simply misread MCMC question and read tablets not injections. It will be a very long time before I do that again, so all I can do is apologise and leave discretely with my tail between my legs. I should have known better, than not to read anything medical twice and keep my mouth shut until I was certain of the facts.

[Hidden in reply to B12Turbo]

Didn't mean it like that B12Turbo, as you know those tablets are a touchy subject with me = bad personal experience. I know you do OK on them.

[MCMC in reply to B12Turbo]

Lol

[B12Turbo]

Hi Hampster 1

Not so any more I'm afraid my friend, yes I've overcome my low Serum level and at present that's fine along with all the other parameters, but I'm working on trying to ascertain if I have a Myelin synthesis problem, which may be resulting in neural damage in the brain, spinal cord and / or peripheral nerves. I have a very painful condition known as Facial Migraine, I have suffered this for some 15 or more years and the Neurology guy's seem to feel that there is no answer to this condition. Everyone agree's that it stems from the 5th Cranial Nerve ( The Trigeminal Nerve ) and I also have a possible problem with the 8th, as I often have problems with balance and hearing. I am about to change my medication over to Methylcobalamin and possibly add Folic Acid + B2 & B6. All my bloods are good, with my last folate at 7.1 on a ( 3 to 20 ) scale. I run regular annual FBC - U's & E's - LFT's etc etc etc. the last only a week or two back. I'm looking for a reliable and clean supply of Methylcobalamin in patches, hopefully this will allow me to get straight into the blood stream and circumvent the gut. If you know of anywhere that can supply such items, I'm looking to start at around 500 to 1000 micro grams, in order to ascertain if I'm likely to suffer any form of side effects, prior to increasing to the 1500 to 5000 level that my research is indicating may be required in order to achieve the desired results. Finding an answer to this problem would be a wonderful outcome, as I get 3 or 4 events each week and each one lasts for between 12 and 30 hours of intense pain and to add to the problem, no pain killers work to any real extent and I can't lay down during an event, as I have to remain seated upright. I guess you can see just why I'm on this quest, as my increased B12 levels have not helped this condition much at all sadly.

Hope things are going well with you at present.

Best regards

B12 Turbo

[MCMC in reply to B12Turbo]

Hi B12 turbo,

I was having terrible migraines and even a suspected stroke, which proved to be migraine attack. After being diagnosed with low vit d levels. I started taking supplements and I have not had a migraine attack since. The consultant at the stroke clinic agreed my migraines could have been due to this. Have you had your vit d levels checked?

I buy sublingual b12 with folic acid and vit c in it from myhealthbasket.co.uk £14.99 for 50 lozenges. Because you suck them, the b12 is absorbed by the sublingual tissues in the mouth. Hopefully dealing with stomach absorption problems.

Regards MCMC

[Chancery in reply to B12Turbo]

Hi B12Turbo, I know this is a very old discussion, but if you see this I would be interested in hearing about your 'facial migraines'. I suffer from Trigeminal Neuralgia and wondered if this is related to your problems (I've never heard of facial migraine before). I'd be curious to know how you got on with B12, as this is used to treat my TN (so far, successfully).

[B12Turbo in reply to Chancery]

Hi Chancery there is a common factor that being the 5th Cranial Nerve the (Trigeminal Nerve). However, I'm afraid that the B12 balance problem appears to differ in each patient. The whole picture as my research over the last 3 years has indicated that it is it is not simply the B12 aspect that is important, but the big picture indicates that it is the full Methylation Cycle that has to be balanced. In this, you may find that although one may be for instance taking Folic Acid at 400ug to 800ug daily, one may also have, for instance, a mutation in your MTFHR Gene. Now if that were to be so, as it is for many people in the population, then the body may not be able to use the FA. In order for the body to make use of FA, it must be broken down to 5MTHF. This substance I believe to be the Methylation Cycle regulator and thus, whilst ones Serum Folate may be indicated as ok, the whole Methylation cycle may be lacking it's regulator and thereby not working as it should. I'm afraid that the subject and implications of the B12 story are like most medical research problems, very complexed. I would say that if you have been taking B12 etc. then you should stop for approximately 2 to 3 months and then talk to your medical advisor about a full range of tests for Intrinsic Factor, Pareital Cell Antibodies, HoloTC, MMA and Homocysteine. Sadly you need to stop taking B12 etc. in order to obtain a base level indication, or if you do not, then all these tests may be corrupted and that will prove nothing. Best wishes B12Turbo.

[Chancery in reply to B12Turbo]

Thanks for getting back to me, Turbo. I assume from what you say that B12 has not been a saviour for you then? That's a great pity. I did have all the tests (except for Homocysteine and MMA, which I missed out on and always regret) right at the outset of my condition, so I don't really need to do them. I get monthly injections and, so far, that controls the pain. I am almost off medications and am hopeful that the B12 will continue to work its magic. Very best of luck with your migraines. I hope you find something that works for you.

[Hidden]

I'm sorry to hear that, although personally I have B12 levels up around 2000 so yours looks quite low to me! I really think you need to be on alternate day injections with the neuro symptoms you describe.

That aside, have you tried supplementing folate before? I think you're level is still a bit on the low side. It is definitely a trigger for my migraines, and I need to stay on a reasonably high dose to keep everything in balance.

I'd say you'd want to try at least 800mcg folate daily, maybe more. I tried maintaining on the 400mcg in my B complex and got deficiency symptoms within a month. I'm back on 5mg daily at the moment. Of course we're all different, but I'm feeling at the moment that folate metabolism/methylation is as big a problem for me as B12.

I've never used the patches myself but I hear good things about them, the only ones I know of are on this page:

pernicious-anaemia-society....

I would recommend having a look at Pure Encapsulations for your other Bs, I use their B-Complex plus. They also do various folate supplements:

pureencapsulations.com/cata...

You can get these from here in the UK, depending on stock:

breakspearstore.co.uk/manuf...

You have to register on their website to see what products are available.

The other suggestion I have, again from personal experience only, is to get your other key minerals tested. Copper deficiency symptoms are similar to B12 deficiency, I was found to be a little low on zinc, copper and magnesium.

I hope you find something that works for you, living with the pain of migraine is no easy thing.

Take care

[B12Turbo]

Hi Guys

Many thanks for your responses, if I may take MCMC first. I fully appreciate your line regarding your own migraines and they sound as though they were indeed intense. However, sadly there are over 40 different types of migraine, with many differing presentations. In my case, I take your point regarding Vit. D, this is needed to convert Calcium in the body and I have found that CCB's ( Calcium Channel Blockers ) will cure my migraine. I took 5mgs of Amlodipene, an input from research conducted by The Australian Brain Foundation and remained migraine free for 12 months, until the manufactures changed the chemical constituents in their make up and this caused me to become intolerant of their product. Months of searching proved no other product on the market existed to which I was not intolerant. Secondly I have considered the sublingual route, but if possible, my preference would be to try patches in the first instance. Many thanks for your inputs, which I have read with great interest and taken on board all you have to say.

Now may I turn my attentions to Hampster1's response. Firstly; as always Hampster, you talk a lot of logical sense, but regarding injections, I originally declined to go that route due to a fear of intolerance, sadly I'm one of those unlucky people who's body seems to reject almost everything, even many foods. My thinking / concept is and it's agreed by most of the people I work with, that once you inject a substance, you can't get it back out, unlike low dose tablets, which you can simply stop taking, or patches that you can just pull off, with a minimum risk of any adverse reaction. Regarding your migraines, of course I know this may sound silly, but I know not if you are male or female, or your age and this can make a difference, particularly regarding hormones etc. In addition the type of migraine, for instance with or without auras, the aspect of neuro symptoms such as pins and needles in the hands and arms, as well as around the mouth, all these things, as I've no doubt you already aware, can constitute aspects of the type of migraine one is suffering, In my case I personally feel and eminent medics agree, my main problem could well stem from my use of drugs which are now known to thin the nasal membrane, a place which has now become the trigger point for initializing my migraine attacks, drugs which cured one problem and possibly left me with yet another. I hear what you say about Folic Acid intakes and I can fully appreciate your learned point of view, for there is no substitute for experience and I doubt anyone who has not lived with migraine problems, to fully understand the intensity of pain they can create, indeed, that is probably why migraine is reputed to be a major cause of suicide. However, back to Folic Acid, I was thinking the same as your goodself and looking at possibly starting at 400mcg. However, I have 3 consultant Haemotologists looking at my overall blood readings and giving consideration to what if anything should be taken. Once I have this consensus of expert opinion, to add to both yours and my own, I will decide upon what I feel to be the best route forward. I'm sorry, but please don't feel I'm not listening, however, 50 year in research and development have taught me to take one step at a time, you know, "Slowly slowly catchy monkey" and all that. My sincere thanks for your time and valued inputs once again, in particular the links to site that might be able to supply my needs. I will also look at the mineral aspects. Thanks again Best wishes B12 Turbo

[Hidden in reply to B12Turbo]

I'm female, early 40s, just to answer one of your questions anyway!

[MCMC in reply to B12Turbo]

Hope you find the answers you need,

Best wishes

MCMC

[B12Turbo]

Hi Hampster

Thought that might be the case from the picture, but one never knows of course. Well I'm male and 70 years old, so I guess our chemistry is going to differ somewhat. The good news is, I have eventually tracked down B12 Methylcobalamin patches 1000mcg with 400mcg of Folic Acid in them, made by Biovea and available from Amazon or Biovea UK. Other patches have included one that contained 150mcg of Vit. K and I certainly don't have a clotting problem, but they also had 9 other vitamins to boot. Personally I prefer to add my own ingredients as I go along. So I'm just about to send for the patches and start looking at what to add next if these sticky bits work out ok. I do feel 1000mcg might be a little on the low side, research shows I may need 1500 to 5000, but I believe in starting low and building up from there. Fingers crossed, let's see what happens next. So tune into the next exciting episode of the "B12 STORY" to be screened in HD with Dolby 5 surround sound.

Many thanks for all your help and interest. B12 Turbo

[sosspain in reply to B12Turbo]

Hi

[sosspain in reply to sosspain]

Hi B12 turbo

First time using this site and have been reading your messages. I am overwhelmed I have suffered daily debilitating migraines (several different types) from age 35 to now age 46 have tried everything including going to america for loads of operations, these did not work so I am pretty much house bound due to them for last 10 years. This is the first I have read about Vit B 12 def having an impact on migraines, I am so excited to see if this applies to me. You stated earlier you have 3 consultant Haemotologists looking at your overall blood readings, do you live in the uk, if yes where can I get these tests done? One thing I have read is that vit b12 is in our cells and testing serum b12 levels is not accurate that the best test is 'intra cellular vit b12 analysis. I don't know anything about this literally found out about it just prior to reading your information. I've looked on amazon for the same patches you have but they don't have that brand so I'll try another to see what happens. like you say patches can always be removed, I was looking into injections but have changed my mind after your advice. Would love to hear if the patches have any impact on your migraines.

I would like to thank you for posting your findings so far there very interesting.

Thanks

[supermic2014]

Check these guys out: goo.gl/TnQ8UA

They ship from the US and I've heard good things about their product!