Hi Everyone. It is Pat. I found the hardest part of treating PD was getting the right mix of medications taken at the right times. It took quite awhile but my Doctor and I feel we have reached that point at least for now. I take three Stalevos a day, mirapex(an-agonist) three times a day,and at bedtime one Sinemet 25-100 and one Lexapro -20 mg right before bed. I sleep like a log and tremors and dyskinesias are much better. I think trial and error ,at least for me, was worth it.